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Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus.
Koop G, Vrieling M, Storisteanu DM, Lok LS, Monie T, van Wigcheren G, Raisen C, Ba X, Gleadall N, Hadjirin N, Timmerman AJ, Wagenaar JA, Klunder HM, Fitzgerald JR, Zadoks R, Paterson GK, Torres C, Waller AS, Loeffler A, Loncaric I, Hoet AE, Bergström K, De Martino L, Pomba C, de Lencastre H, Ben Slama K, Gharsa H, Richardson EJ, Chilvers ER, de Haas C, van Kessel K, van Strijp JA, Harrison EM, Holmes MA. Koop G, et al. Among authors: de martino l, de lencastre h, de haas c. Sci Rep. 2017 Jan 20;7:40660. doi: 10.1038/srep40660. Sci Rep. 2017. PMID: 28106142 Free PMC article.
High prevalence of ST121 in community-associated methicillin-susceptible Staphylococcus aureus lineages responsible for skin and soft tissue infections in Portuguese children.
Conceição T, Aires-de-Sousa M, Pona N, Brito MJ, Barradas C, Coelho R, Sardinha T, Sancho L, de Sousa G, Machado Mdo C, de Lencastre H. Conceição T, et al. Among authors: de lencastre h, de sousa g. Eur J Clin Microbiol Infect Dis. 2011 Feb;30(2):293-7. doi: 10.1007/s10096-010-1087-8. Epub 2010 Nov 3. Eur J Clin Microbiol Infect Dis. 2011. PMID: 21046422
A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic.
Holden MT, Hsu LY, Kurt K, Weinert LA, Mather AE, Harris SR, Strommenger B, Layer F, Witte W, de Lencastre H, Skov R, Westh H, Zemlicková H, Coombs G, Kearns AM, Hill RL, Edgeworth J, Gould I, Gant V, Cooke J, Edwards GF, McAdam PR, Templeton KE, McCann A, Zhou Z, Castillo-Ramírez S, Feil EJ, Hudson LO, Enright MC, Balloux F, Aanensen DM, Spratt BG, Fitzgerald JR, Parkhill J, Achtman M, Bentley SD, Nübel U. Holden MT, et al. Among authors: de lencastre h. Genome Res. 2013 Apr;23(4):653-64. doi: 10.1101/gr.147710.112. Epub 2013 Jan 8. Genome Res. 2013. PMID: 23299977 Free PMC article.
First insights of peptidoglycan amidation in Gram-positive bacteria - the high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD.
Leisico F, V Vieira D, Figueiredo TA, Silva M, Cabrita EJ, Sobral RG, Ludovice AM, Trincão J, Romão MJ, de Lencastre H, Santos-Silva T. Leisico F, et al. Among authors: de lencastre h. Sci Rep. 2018 Mar 28;8(1):5313. doi: 10.1038/s41598-018-22986-3. Sci Rep. 2018. PMID: 29593310 Free PMC article.
Emergence of methicillin resistance predates the clinical use of antibiotics.
Larsen J, Raisen CL, Ba X, Sadgrove NJ, Padilla-González GF, Simmonds MSJ, Loncaric I, Kerschner H, Apfalter P, Hartl R, Deplano A, Vandendriessche S, Černá Bolfíková B, Hulva P, Arendrup MC, Hare RK, Barnadas C, Stegger M, Sieber RN, Skov RL, Petersen A, Angen Ø, Rasmussen SL, Espinosa-Gongora C, Aarestrup FM, Lindholm LJ, Nykäsenoja SM, Laurent F, Becker K, Walther B, Kehrenberg C, Cuny C, Layer F, Werner G, Witte W, Stamm I, Moroni P, Jørgensen HJ, de Lencastre H, Cercenado E, García-Garrote F, Börjesson S, Hæggman S, Perreten V, Teale CJ, Waller AS, Pichon B, Curran MD, Ellington MJ, Welch JJ, Peacock SJ, Seilly DJ, Morgan FJE, Parkhill J, Hadjirin NF, Lindsay JA, Holden MTG, Edwards GF, Foster G, Paterson GK, Didelot X, Holmes MA, Harrison EM, Larsen AR. Larsen J, et al. Among authors: de lencastre h. Nature. 2022 Feb;602(7895):135-141. doi: 10.1038/s41586-021-04265-w. Epub 2022 Jan 5. Nature. 2022. PMID: 34987223 Free PMC article.
New mechanism for methicillin resistance in Staphylococcus aureus: clinical isolates that lack the PBP 2a gene and contain normal penicillin-binding proteins with modified penicillin-binding capacity.
Tomasz A, Drugeon HB, de Lencastre HM, Jabes D, McDougall L, Bille J. Tomasz A, et al. Among authors: de lencastre hm. Antimicrob Agents Chemother. 1989 Nov;33(11):1869-74. doi: 10.1128/AAC.33.11.1869. Antimicrob Agents Chemother. 1989. PMID: 2610497 Free PMC article.
313 results