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Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
Franklin BS, Parroche P, Ataíde MA, Lauw F, Ropert C, de Oliveira RB, Pereira D, Tada MS, Nogueira P, da Silva LH, Bjorkbacka H, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Among authors: de oliveira rb. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5789-94. doi: 10.1073/pnas.0809742106. Epub 2009 Mar 18. Proc Natl Acad Sci U S A. 2009. PMID: 19297619 Free PMC article.
Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria.
Franklin BS, Ishizaka ST, Lamphier M, Gusovsky F, Hansen H, Rose J, Zheng W, Ataíde MA, de Oliveira RB, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Among authors: de oliveira rb. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3689-94. doi: 10.1073/pnas.1015406108. Epub 2011 Feb 8. Proc Natl Acad Sci U S A. 2011. PMID: 21303985 Free PMC article.
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.
Hirako IC, Gallego-Marin C, Ataide MA, Andrade WA, Gravina H, Rocha BC, de Oliveira RB, Pereira DB, Vinetz J, Diamond B, Ram S, Golenbock DT, Gazzinelli RT. Hirako IC, et al. Among authors: de oliveira rb. mBio. 2015 Nov 17;6(6):e01605-15. doi: 10.1128/mBio.01605-15. mBio. 2015. PMID: 26578679 Free PMC article.
Hemolysis-induced lethality involves inflammasome activation by heme.
Dutra FF, Alves LS, Rodrigues D, Fernandez PL, de Oliveira RB, Golenbock DT, Zamboni DS, Bozza MT. Dutra FF, et al. Among authors: de oliveira rb. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4110-8. doi: 10.1073/pnas.1405023111. Epub 2014 Sep 15. Proc Natl Acad Sci U S A. 2014. PMID: 25225402 Free PMC article.
Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens.
Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier GB. Cywes-Bentley C, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2209-18. doi: 10.1073/pnas.1303573110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716675 Free PMC article.
Interferon-γ and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).
Souza-Fonseca-Guimaraes F, Parlato M, de Oliveira RB, Golenbock D, Fitzgerald K, Shalova IN, Biswas SK, Cavaillon JM, Adib-Conquy M. Souza-Fonseca-Guimaraes F, et al. Among authors: de oliveira rb. J Biol Chem. 2013 Apr 12;288(15):10715-21. doi: 10.1074/jbc.M112.435602. Epub 2013 Feb 26. J Biol Chem. 2013. PMID: 23443666 Free PMC article.
RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.
Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT. Gupta R, et al. J Biol Chem. 2014 May 16;289(20):13701-5. doi: 10.1074/jbc.C114.548982. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692555 Free PMC article.
259 results