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155 results
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Targeting the Hedgehog pathway in cancer.
Rubin LL, de Sauvage FJ. Rubin LL, et al. Among authors: de sauvage fj. Nat Rev Drug Discov. 2006 Dec;5(12):1026-33. doi: 10.1038/nrd2086. Nat Rev Drug Discov. 2006. PMID: 17139287 Review.
The hedgehog signaling pathway in cancer.
Evangelista M, Tian H, de Sauvage FJ. Evangelista M, et al. Among authors: de sauvage fj. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):5924-8. doi: 10.1158/1078-0432.CCR-06-1736. Clin Cancer Res. 2006. PMID: 17062662 Review.
A paracrine requirement for hedgehog signalling in cancer.
Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP, Marshall D, Fu L, Januario T, Kallop D, Nannini-Pepe M, Kotkow K, Marsters JC, Rubin LL, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Nature. 2008 Sep 18;455(7211):406-10. doi: 10.1038/nature07275. Epub 2008 Aug 27. Nature. 2008. PMID: 18754008
Paracrine Hedgehog signaling in cancer.
Theunissen JW, de Sauvage FJ. Theunissen JW, et al. Among authors: de sauvage fj. Cancer Res. 2009 Aug 1;69(15):6007-10. doi: 10.1158/0008-5472.CAN-09-0756. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638582 Review.
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.
Rudin CM, Hann CL, Laterra J, Yauch RL, Callahan CA, Fu L, Holcomb T, Stinson J, Gould SE, Coleman B, LoRusso PM, Von Hoff DD, de Sauvage FJ, Low JA. Rudin CM, et al. Among authors: de sauvage fj. N Engl J Med. 2009 Sep 17;361(12):1173-8. doi: 10.1056/NEJMoa0902903. Epub 2009 Sep 2. N Engl J Med. 2009. PMID: 19726761 Free PMC article.
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.
Von Hoff DD, LoRusso PM, Rudin CM, Reddy JC, Yauch RL, Tibes R, Weiss GJ, Borad MJ, Hann CL, Brahmer JR, Mackey HM, Lum BL, Darbonne WC, Marsters JC Jr, de Sauvage FJ, Low JA. Von Hoff DD, et al. Among authors: de sauvage fj. N Engl J Med. 2009 Sep 17;361(12):1164-72. doi: 10.1056/NEJMoa0905360. Epub 2009 Sep 2. N Engl J Med. 2009. PMID: 19726763 Clinical Trial.
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