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Influence of tumour micro-environment heterogeneity on therapeutic response.
Junttila MR, de Sauvage FJ. Junttila MR, et al. Among authors: de sauvage fj. Nature. 2013 Sep 19;501(7467):346-54. doi: 10.1038/nature12626. Nature. 2013. PMID: 24048067 Review.
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.
Parker LH, Schmidt M, Jin SW, Gray AM, Beis D, Pham T, Frantz G, Palmieri S, Hillan K, Stainier DY, De Sauvage FJ, Ye W. Parker LH, et al. Among authors: de sauvage fj. Nature. 2004 Apr 15;428(6984):754-8. doi: 10.1038/nature02416. Nature. 2004. PMID: 15085134
Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers.
Gray D, Jubb AM, Hogue D, Dowd P, Kljavin N, Yi S, Bai W, Frantz G, Zhang Z, Koeppen H, de Sauvage FJ, Davis DP. Gray D, et al. Among authors: de sauvage fj. Cancer Res. 2005 Nov 1;65(21):9751-61. doi: 10.1158/0008-5472.CAN-04-4531. Cancer Res. 2005. PMID: 16266996
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation.
Wang XD, Leow CC, Zha J, Tang Z, Modrusan Z, Radtke F, Aguet M, de Sauvage FJ, Gao WQ. Wang XD, et al. Among authors: de sauvage fj. Dev Biol. 2006 Feb 1;290(1):66-80. doi: 10.1016/j.ydbio.2005.11.009. Epub 2005 Dec 15. Dev Biol. 2006. PMID: 16360140
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells.
Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, Lucas S, Lee J, de Sauvage FJ, Ghilardi N. Batten M, et al. Among authors: de sauvage fj. Nat Immunol. 2006 Sep;7(9):929-36. doi: 10.1038/ni1375. Epub 2006 Aug 13. Nat Immunol. 2006. PMID: 16906167
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.
Peters BA, Kan Z, Sebisanovic D, Pujara K, Wang Z, Hong P, Chow B, Stinson J, Carlton VE, Pham TQ, Stern H, Waring P, Hillan KJ, Eberhard DA, de Sauvage F, Zheng J, Faham M, Seshagiri S. Peters BA, et al. Among authors: de sauvage f. Nat Methods. 2007 Sep;4(9):713-5. doi: 10.1038/nmeth1081. Epub 2007 Aug 19. Nat Methods. 2007. PMID: 17704782
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens.
Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, Ouyang W. Zheng Y, et al. Among authors: de sauvage fj. Nat Med. 2008 Mar;14(3):282-9. doi: 10.1038/nm1720. Epub 2008 Feb 10. Nat Med. 2008. PMID: 18264109
A paracrine requirement for hedgehog signalling in cancer.
Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP, Marshall D, Fu L, Januario T, Kallop D, Nannini-Pepe M, Kotkow K, Marsters JC, Rubin LL, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Nature. 2008 Sep 18;455(7211):406-10. doi: 10.1038/nature07275. Epub 2008 Aug 27. Nature. 2008. PMID: 18754008
Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
Tian H, Callahan CA, DuPree KJ, Darbonne WC, Ahn CP, Scales SJ, de Sauvage FJ. Tian H, et al. Among authors: de sauvage fj. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4254-9. doi: 10.1073/pnas.0813203106. Epub 2009 Feb 25. Proc Natl Acad Sci U S A. 2009. PMID: 19246386 Free PMC article.
Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.
Scales SJ, de Sauvage FJ. Scales SJ, et al. Among authors: de sauvage fj. Trends Pharmacol Sci. 2009 Jun;30(6):303-12. doi: 10.1016/j.tips.2009.03.007. Epub 2009 May 13. Trends Pharmacol Sci. 2009. PMID: 19443052 Review.
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