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Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager.
J Immunother Cancer. 2019 Jan 25;7(1):19. doi: 10.1186/s40425-019-0505-4.
J Immunother Cancer. 2019.
PMID: 30683154
Free PMC article.
Oncolytic Adenoviral Delivery of an EGFR-Targeting T-cell Engager Improves Antitumor Efficacy.
Fajardo CA, Guedan S, Rojas LA, Moreno R, Arias-Badia M, de Sostoa J, June CH, Alemany R.
Fajardo CA, et al. Among authors: de sostoa j.
Cancer Res. 2017 Apr 15;77(8):2052-2063. doi: 10.1158/0008-5472.CAN-16-1708. Epub 2017 Jan 31.
Cancer Res. 2017.
PMID: 28143835
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Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus.
Al-Zaher AA, Moreno R, Fajardo CA, Arias-Badia M, Farrera M, de Sostoa J, Rojas LA, Alemany R.
Al-Zaher AA, et al. Among authors: de sostoa j.
Mol Ther Oncolytics. 2018 Jan 31;8:62-70. doi: 10.1016/j.omto.2018.01.003. eCollection 2018 Mar 30.
Mol Ther Oncolytics. 2018.
PMID: 29888319
Free PMC article.
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Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness.
Farrera-Sal M, de Sostoa J, Nuñez-Manchón E, Moreno R, Fillat C, Bazan-Peregrino M, Alemany R.
Farrera-Sal M, et al. Among authors: de sostoa j.
Int J Mol Sci. 2020 Jul 21;21(14):5158. doi: 10.3390/ijms21145158.
Int J Mol Sci. 2020.
PMID: 32708234
Free PMC article.
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Cancer Stem-like Cells Act via Distinct Signaling Pathways in Promoting Late Stages of Malignant Progression.
da Silva-Diz V, Simón-Extremera P, Bernat-Peguera A, de Sostoa J, Urpí M, Penín RM, Sidelnikova DP, Bermejo O, Viñals JM, Rodolosse A, González-Suárez E, Moruno AG, Pujana MÁ, Esteller M, Villanueva A, Viñals F, Muñoz P.
da Silva-Diz V, et al. Among authors: de sostoa j.
Cancer Res. 2016 Mar 1;76(5):1245-59. doi: 10.1158/0008-5472.CAN-15-1631. Epub 2015 Dec 30.
Cancer Res. 2016.
PMID: 26719534
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