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The inflammatory tumor microenvironment and its impact on cancer development.
de Visser KE, Coussens LM. de Visser KE, et al. Contrib Microbiol. 2006;13:118-137. doi: 10.1159/000092969. Contrib Microbiol. 2006. PMID: 16627962 Review.
Identification of peptides for immunotherapy of cancer. It is worth the effort.
Velders MP, Nieland JD, Rudolf MP, Loviscek K, Weijzen S, de Visser KE, Macedo MF, Carbone M, Kast WM. Velders MP, et al. Crit Rev Immunol. 1998;18(1-2):7-27. doi: 10.1615/critrevimmunol.v18.i1-2.30. Crit Rev Immunol. 1998. PMID: 9419444 Review.
Tumor size at the time of adoptive transfer determines whether tumor rejection occurs.
Cordaro TA, de Visser KE, Tirion FH, Graus YM, Haanen JB, Kioussis D, Kruisbeek AM. Cordaro TA, et al. Eur J Immunol. 2000 May;30(5):1297-307. doi: 10.1002/(SICI)1521-4141(200005)30:5<1297::AID-IMMU1297>3.0.CO;2-C. Eur J Immunol. 2000. PMID: 10820375
Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection?
Cordaro TA, de Visser KE, Tirion FH, Schumacher TN, Kruisbeek AM. Cordaro TA, et al. J Immunol. 2002 Jan 15;168(2):651-60. doi: 10.4049/jimmunol.168.2.651. J Immunol. 2002. PMID: 11777958
CD8+ T cell tolerance and cancer immunotherapy.
De Visser KE, Schumacher TN, Kruisbeek AM. De Visser KE, et al. J Immunother. 2003 Jan-Feb;26(1):1-11. doi: 10.1097/00002371-200301000-00001. J Immunother. 2003. PMID: 12514424 Review.
The impact of self-tolerance on the polyclonal CD8+ T cell repertoire.
Kessels HW, de Visser KE, Tirion FH, Coccoris M, Kruisbeek AM, Schumacher TN. Kessels HW, et al. J Immunol. 2004 Feb 15;172(4):2324-31. doi: 10.4049/jimmunol.172.4.2324. J Immunol. 2004. PMID: 14764701
Early neoplastic progression is complement independent.
de Visser KE, Korets LV, Coussens LM. de Visser KE, et al. Neoplasia. 2004 Nov-Dec;6(6):768-76. doi: 10.1593/neo.04250. Neoplasia. 2004. PMID: 15720803 Free PMC article.
The interplay between innate and adaptive immunity regulates cancer development.
de Visser KE, Coussens LM. de Visser KE, et al. Cancer Immunol Immunother. 2005 Nov;54(11):1143-52. doi: 10.1007/s00262-005-0702-5. Epub 2005 May 12. Cancer Immunol Immunother. 2005. PMID: 15889249 Review.
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent.
de Visser KE, Korets LV, Coussens LM. de Visser KE, et al. Cancer Cell. 2005 May;7(5):411-23. doi: 10.1016/j.ccr.2005.04.014. Cancer Cell. 2005. PMID: 15894262
We report that genetic elimination of mature T and B lymphocytes in a transgenic mouse model of inflammation-associated de novo epithelial carcinogenesis, e.g., K14-HPV16 mice, limits neoplastic progression to development of epithelial hyperplasias that fail to recruit inn …
We report that genetic elimination of mature T and B lymphocytes in a transgenic mouse model of inflammation-associated de novo epith …
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