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83 results
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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
Wiesmann C, Ultsch MH, Bass SH, de Vos AM. Wiesmann C, et al. Among authors: de vos am. Nature. 1999 Sep 9;401(6749):184-8. doi: 10.1038/43705. Nature. 1999. PMID: 10490030
Suppressor of fused regulates Gli activity through a dual binding mechanism.
Merchant M, Vajdos FF, Ultsch M, Maun HR, Wendt U, Cannon J, Desmarais W, Lazarus RA, de Vos AM, de Sauvage FJ. Merchant M, et al. Among authors: de vos am, de sauvage fj. Mol Cell Biol. 2004 Oct;24(19):8627-41. doi: 10.1128/MCB.24.19.8627-8641.2004. Mol Cell Biol. 2004. PMID: 15367681 Free PMC article.
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Franklin MC, Carey KD, Vajdos FF, Leahy DJ, de Vos AM, Sliwkowski MX. Franklin MC, et al. Among authors: de vos am. Cancer Cell. 2004 Apr;5(4):317-28. doi: 10.1016/s1535-6108(04)00083-2. Cancer Cell. 2004. PMID: 15093539
The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1.
Christinger HW, Fuh G, de Vos AM, Wiesmann C. Christinger HW, et al. Among authors: de vos am. J Biol Chem. 2004 Mar 12;279(11):10382-8. doi: 10.1074/jbc.M313237200. Epub 2003 Dec 18. J Biol Chem. 2004. PMID: 14684734
The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. Hymowitz SG, et al. Among authors: de vos am. Structure. 2003 Dec;11(12):1513-20. doi: 10.1016/j.str.2003.11.009. Structure. 2003. PMID: 14656435
Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
Vajdos FF, Adams CW, Breece TN, Presta LG, de Vos AM, Sidhu SS. Vajdos FF, et al. Among authors: de vos am. J Mol Biol. 2002 Jul 5;320(2):415-28. doi: 10.1016/S0022-2836(02)00264-4. J Mol Biol. 2002. PMID: 12079396
Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites.
Schiffer C, Ultsch M, Walsh S, Somers W, de Vos AM, Kossiakoff A. Schiffer C, et al. Among authors: de vos am. J Mol Biol. 2002 Feb 15;316(2):277-89. doi: 10.1006/jmbi.2001.5348. J Mol Biol. 2002. PMID: 11851338
KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF.
Li B, Ogasawara AK, Yang R, Wei W, He GW, Zioncheck TF, Bunting S, de Vos AM, Jin H. Li B, et al. Among authors: de vos am. Hypertension. 2002 Jun;39(6):1095-100. doi: 10.1161/01.hyp.0000018588.56950.7a. Hypertension. 2002. PMID: 12052848
Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: relative roles of KDR and Flt-1 receptors.
Yang S, Toy K, Ingle G, Zlot C, Williams PM, Fuh G, Li B, de Vos A, Gerritsen ME. Yang S, et al. Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1797-803. doi: 10.1161/01.atv.0000038995.31179.24. Arterioscler Thromb Vasc Biol. 2002. PMID: 12426207
Comparison between light induced and chemically induced oxidation of rhVEGF.
Duenas ET, Keck R, De Vos A, Jones AJ, Cleland JL. Duenas ET, et al. Pharm Res. 2001 Oct;18(10):1455-60. doi: 10.1023/a:1012261024249. Pharm Res. 2001. PMID: 11697472
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