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The single-cell eQTLGen consortium.
van der Wijst M, de Vries DH, Groot HE, Trynka G, Hon CC, Bonder MJ, Stegle O, Nawijn MC, Idaghdour Y, van der Harst P, Ye CJ, Powell J, Theis FJ, Mahfouz A, Heinig M, Franke L. van der Wijst M, et al. Among authors: de vries dh. Elife. 2020 Mar 9;9:e52155. doi: 10.7554/eLife.52155. Elife. 2020. PMID: 32149610 Free PMC article.
Deconvolution of bulk blood eQTL effects into immune cell subpopulations.
Aguirre-Gamboa R, de Klein N, di Tommaso J, Claringbould A, van der Wijst MG, de Vries D, Brugge H, Oelen R, Võsa U, Zorro MM, Chu X, Bakker OB, Borek Z, Ricaño-Ponce I, Deelen P, Xu CJ, Swertz M, Jonkers I, Withoff S, Joosten I, Sanna S, Kumar V, Koenen HJPM, Joosten LAB, Netea MG, Wijmenga C; BIOS Consortium; Franke L, Li Y. Aguirre-Gamboa R, et al. BMC Bioinformatics. 2020 Jun 12;21(1):243. doi: 10.1186/s12859-020-03576-5. BMC Bioinformatics. 2020. PMID: 32532224 Free PMC article.
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.
Võsa U, Claringbould A, Westra HJ, Bonder MJ, Deelen P, Zeng B, Kirsten H, Saha A, Kreuzhuber R, Yazar S, Brugge H, Oelen R, de Vries DH, van der Wijst MGP, Kasela S, Pervjakova N, Alves I, Favé MJ, Agbessi M, Christiansen MW, Jansen R, Seppälä I, Tong L, Teumer A, Schramm K, Hemani G, Verlouw J, Yaghootkar H, Sönmez Flitman R, Brown A, Kukushkina V, Kalnapenkis A, Rüeger S, Porcu E, Kronberg J, Kettunen J, Lee B, Zhang F, Qi T, Hernandez JA, Arindrarto W, Beutner F; BIOS Consortium; i2QTL Consortium; Dmitrieva J, Elansary M, Fairfax BP, Georges M, Heijmans BT, Hewitt AW, Kähönen M, Kim Y, Knight JC, Kovacs P, Krohn K, Li S, Loeffler M, Marigorta UM, Mei H, Momozawa Y, Müller-Nurasyid M, Nauck M, Nivard MG, Penninx BWJH, Pritchard JK, Raitakari OT, Rotzschke O, Slagboom EP, Stehouwer CDA, Stumvoll M, Sullivan P, 't Hoen PAC, Thiery J, Tönjes A, van Dongen J, van Iterson M, Veldink JH, Völker U, Warmerdam R, Wijmenga C, Swertz M, Andiappan A, Montgomery GW, Ripatti S, Perola M, Kutalik Z, Dermitzakis E, Bergmann S, Frayling T, van Meurs J, Prokisch H, Ahsan H, Pierce BL, Lehtimäki T, Boomsma DI, Psaty BM, Gharib SA, Awadalla P, Milani L, Ouwehand WH, Downes K, Stegle O, Batt… See abstract for full author list ➔ Võsa U, et al. Among authors: de vries dh. Nat Genet. 2021 Sep;53(9):1300-1310. doi: 10.1038/s41588-021-00913-z. Epub 2021 Sep 2. Nat Genet. 2021. PMID: 34475573 Free PMC article.
Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure.
Oelen R, de Vries DH, Brugge H, Gordon MG, Vochteloo M; single-cell eQTLGen consortium; BIOS Consortium; Ye CJ, Westra HJ, Franke L, van der Wijst MGP. Oelen R, et al. Among authors: de vries dh. Nat Commun. 2022 Jun 7;13(1):3267. doi: 10.1038/s41467-022-30893-5. Nat Commun. 2022. PMID: 35672358 Free PMC article.
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data.
Li S, Schmid KT, de Vries DH, Korshevniuk M, Losert C, Oelen R, van Blokland IV; BIOS Consortium, sc-eQTLgen Consortium; Groot HE, Swertz MA, van der Harst P, Westra HJ, van der Wijst MGP, Heinig M, Franke L. Li S, et al. Among authors: de vries dh. Genome Biol. 2023 Apr 18;24(1):80. doi: 10.1186/s13059-023-02897-x. Genome Biol. 2023. PMID: 37072791 Free PMC article.
42 results