de Waart DR - Search Results

1

Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene.

Manautou JE, de Waart DR, Kunne C, Zelcer N, Goedken M, Borst P, Elferink RO. Manautou JE, et al. Among authors: de waart dr. Hepatology. 2005 Nov;42(5):1091-8. doi: 10.1002/hep.20898. Hepatology. 2005. PMID: 16250050

2

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

Vlaming ML, Mohrmann K, Wagenaar E, de Waart DR, Elferink RP, Lagas JS, van Tellingen O, Vainchtein LD, Rosing H, Beijnen JH, Schellens JH, Schinkel AH. Vlaming ML, et al. Among authors: de waart dr. J Pharmacol Exp Ther. 2006 Jul;318(1):319-27. doi: 10.1124/jpet.106.101774. Epub 2006 Apr 12. J Pharmacol Exp Ther. 2006. PMID: 16611851

3

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity.

Paulusma CC, Folmer DE, Ho-Mok KS, de Waart DR, Hilarius PM, Verhoeven AJ, Oude Elferink RP. Paulusma CC, et al. Among authors: de waart dr. Hepatology. 2008 Jan;47(1):268-78. doi: 10.1002/hep.21950. Hepatology. 2008. PMID: 17948906

4

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH. Vlaming ML, et al. Among authors: de waart dr. Clin Cancer Res. 2008 Dec 15;14(24):8152-60. doi: 10.1158/1078-0432.CCR-08-1609. Clin Cancer Res. 2008. PMID: 19088030

5

Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity.

Kunne C, Acco A, Hohenester S, Duijst S, de Waart DR, Zamanbin A, Oude Elferink RP. Kunne C, et al. Among authors: de waart dr. Hepatology. 2013 Apr;57(4):1509-17. doi: 10.1002/hep.26133. Epub 2013 Jan 18. Hepatology. 2013. PMID: 23184615

6

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.

Slijepcevic D, Kaufman C, Wichers CG, Gilglioni EH, Lempp FA, Duijst S, de Waart DR, Elferink RP, Mier W, Stieger B, Beuers U, Urban S, van de Graaf SF. Slijepcevic D, et al. Among authors: de waart dr. Hepatology. 2015 Jul;62(1):207-19. doi: 10.1002/hep.27694. Epub 2015 May 8. Hepatology. 2015. PMID: 25641256 Free PMC article.

7

ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes.

de Waart DR, Naik J, Utsunomiya KS, Duijst S, Ho-Mok K, Bolier AR, Hiralall J, Bull LN, Bosma PJ, Oude Elferink RP, Paulusma CC. de Waart DR, et al. Hepatology. 2016 Jul;64(1):161-74. doi: 10.1002/hep.28522. Epub 2016 Apr 6. Hepatology. 2016. PMID: 26926206 Free PMC article.

8

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.

Slijepcevic D, Roscam Abbing RLP, Katafuchi T, Blank A, Donkers JM, van Hoppe S, de Waart DR, Tolenaars D, van der Meer JHM, Wildenberg M, Beuers U, Oude Elferink RPJ, Schinkel AH, van de Graaf SFJ. Slijepcevic D, et al. Among authors: de waart dr. Hepatology. 2017 Nov;66(5):1631-1643. doi: 10.1002/hep.29251. Epub 2017 Sep 29. Hepatology. 2017. PMID: 28498614 Free PMC article.

9

Reduced spontaneous itch in mouse models of cholestasis.

Langedijk J, Bolier R, Tolenaars D, Ten Bloemendaal L, Duijst S, de Waart D, Beuers U, Bosma P, Elferink RO. Langedijk J, et al. Sci Rep. 2021 Mar 17;11(1):6127. doi: 10.1038/s41598-021-85660-1. Sci Rep. 2021. PMID: 33731871 Free PMC article.

10

Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice.

Aronson SJ, Bakker RS, Shi X, Duijst S, Ten Bloemendaal L, de Waart DR, Verheij J, Ronzitti G, Oude Elferink RP, Beuers U, Paulusma CC, Bosma PJ. Aronson SJ, et al. Among authors: de waart dr. J Hepatol. 2019 Jul;71(1):153-162. doi: 10.1016/j.jhep.2019.03.021. Epub 2019 Mar 29. J Hepatol. 2019. PMID: 30935993 Free article.

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