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Page 1
A Ketone Ester Drink Lowers Human Ghrelin and Appetite.
Stubbs BJ, Cox PJ, Evans RD, Cyranka M, Clarke K, de Wet H. Stubbs BJ, et al. Among authors: de wet h. Obesity (Silver Spring). 2018 Feb;26(2):269-273. doi: 10.1002/oby.22051. Epub 2017 Nov 6. Obesity (Silver Spring). 2018. PMID: 29105987 Free PMC article. Clinical Trial.
Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.
Cyranka M, Veprik A, McKay EJ, van Loon N, Thijsse A, Cotter L, Hare N, Saibudeen A, Lingam S, Pires E, Larraufie P, Reimann F, Gribble F, Stewart M, Bentley E, Lear P, McCullagh J, Cantley J, Cox RD, de Wet H. Cyranka M, et al. Among authors: de wet h. Obesity (Silver Spring). 2019 Aug;27(8):1292-1304. doi: 10.1002/oby.22521. Obesity (Silver Spring). 2019. PMID: 31338999 Free PMC article.
The release of GLP-1 from gut L cells is inhibited by low extracellular pH.
Garbutt P, Cyranka M, Michl J, Maejima Y, Vedovato N, Shimomura K, Swietach P, de Wet H. Garbutt P, et al. Among authors: de wet h. Obesity (Silver Spring). 2024 Oct;32(10):1819-1824. doi: 10.1002/oby.24125. Epub 2024 Sep 5. Obesity (Silver Spring). 2024. PMID: 39238194 Free PMC article.
Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion.
Veprik A, Denwood G, Liu D, Bany Bakar R, Morfin V, McHugh K, Tebeka NN, Vetterli L, Yonova-Doing E, Gribble F, Reimann F, Hoehn KL, Hemsley PA, Ahnfelt-Rønne J, Rorsman P, Zhang Q, de Wet H, Cantley J. Veprik A, et al. Among authors: de wet h. Commun Biol. 2022 Mar 18;5(1):238. doi: 10.1038/s42003-022-03170-w. Commun Biol. 2022. PMID: 35304577 Free PMC article.
Studies of the ATPase activity of the ABC protein SUR1.
de Wet H, Mikhailov MV, Fotinou C, Dreger M, Craig TJ, Vénien-Bryan C, Ashcroft FM. de Wet H, et al. FEBS J. 2007 Jul;274(14):3532-3544. doi: 10.1111/j.1742-4658.2007.05879.x. Epub 2007 Jun 11. FEBS J. 2007. PMID: 17561960 Free article.
71 results