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SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, Johnson LB, McGee SF, Lundberg E, Naicker K, Klinger R, Kampf C, Asplund A, Wester K, Gry M, Bjartell A, Gallagher WM, Rexhepaj E, Kilpinen S, Kallioniemi OP, Belt E, Goos J, Meijer G, Birgisson H, Glimelius B, Borrebaeck CA, Navani S, Uhlén M, O'Connor DP, Jirström K, Pontén F. Magnusson K, et al. Am J Surg Pathol. 2011 Jul;35(7):937-48. doi: 10.1097/PAS.0b013e31821c3dae. Am J Surg Pathol. 2011. PMID: 21677534
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Sillars-Hardebol AH, Carvalho B, Beliën JA, de Wit M, Delis-van Diemen PM, Tijssen M, van de Wiel MA, Pontén F, Fijneman RJ, Meijer GA. Sillars-Hardebol AH, et al. J Pathol. 2012 Feb;226(3):442-50. doi: 10.1002/path.2983. Epub 2011 Oct 18. J Pathol. 2012. PMID: 22009326
Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer.
Fijneman RJ, de Wit M, Pourghiasian M, Piersma SR, Pham TV, Warmoes MO, Lavaei M, Piso C, Smit F, Delis-van Diemen PM, van Turenhout ST, Terhaar sive Droste JS, Mulder CJ, Blankenstein MA, Robanus-Maandag EC, Smits R, Fodde R, van Hinsbergh VW, Meijer GA, Jimenez CR. Fijneman RJ, et al. Clin Cancer Res. 2012 May 1;18(9):2613-24. doi: 10.1158/1078-0432.CCR-11-1937. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351690
The cancer secretome, current status and opportunities in the lung, breast and colorectal cancer context.
Schaaij-Visser TB, de Wit M, Lam SW, Jiménez CR. Schaaij-Visser TB, et al. Biochim Biophys Acta. 2013 Nov;1834(11):2242-58. doi: 10.1016/j.bbapap.2013.01.029. Epub 2013 Jan 31. Biochim Biophys Acta. 2013. PMID: 23376433 Review.
Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling.
de Wit M, Kant H, Piersma SR, Pham TV, Mongera S, van Berkel MP, Boven E, Pontén F, Meijer GA, Jimenez CR, Fijneman RJ. de Wit M, et al. J Proteomics. 2014 Mar 17;99:26-39. doi: 10.1016/j.jprot.2014.01.001. Epub 2014 Jan 10. J Proteomics. 2014. PMID: 24418523 Clinical Trial.
Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.
Bosch LJW, de Wit M, Pham TV, Coupé VMH, Hiemstra AC, Piersma SR, Oudgenoeg G, Scheffer GL, Mongera S, Sive Droste JT, Oort FA, van Turenhout ST, Larbi IB, Louwagie J, van Criekinge W, van der Hulst RWM, Mulder CJJ, Carvalho B, Fijneman RJA, Jimenez CR, Meijer GA. Bosch LJW, et al. Ann Intern Med. 2017 Dec 19;167(12):855-866. doi: 10.7326/M17-1068. Epub 2017 Nov 21. Ann Intern Med. 2017. PMID: 29159365
Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.
Komor MA, Bosch LJ, Coupé VM, Rausch C, Pham TV, Piersma SR, Mongera S, Mulder CJ, Dekker E, Kuipers EJ, van de Wiel MA, Carvalho B, Fijneman RJ, Jimenez CR, Meijer GA, de Wit M. Komor MA, et al. J Pathol. 2020 Mar;250(3):288-298. doi: 10.1002/path.5369. Epub 2020 Jan 13. J Pathol. 2020. PMID: 31784980 Free PMC article.
MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.
Lenos K, Goos JA, Vuist IM, den Uil SH, Delis-van Diemen PM, Belt EJ, Stockmann HB, Bril H, de Wit M, Carvalho B, Giblett S, Pritchard CA, Meijer GA, van Kooyk Y, Fijneman RJ, van Vliet SJ. Lenos K, et al. Oncotarget. 2015 Sep 22;6(28):26278-90. doi: 10.18632/oncotarget.4495. Oncotarget. 2015. PMID: 26172302 Free PMC article.
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