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[Rational antibiotic prescribing. Challenges and successes].
Kern WV, de With K. Kern WV, et al. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Nov;55(11-12):1418-26. doi: 10.1007/s00103-012-1557-5. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012. PMID: 23114441 German.
Other examples are the recently improved program for continuous hospital antibiotic use, surveillance and feedback and the Antibiotic Stewardship (ABS) training program with establishment of an ABS expert network. ...
Other examples are the recently improved program for continuous hospital antibiotic use, surveillance and feedback and the Antibiotic Stewar …
Glycopeptide use at four university hospitals in southern Germany.
Kern WV, de With K, Trautmann M, Kern P, Gonnermann C. Kern WV, et al. Infection. 2002 Oct;30(5):262-6. doi: 10.1007/s15010-002-2161-7. Infection. 2002. PMID: 12382083 Clinical Trial.
At one of the hospitals with comparatively low glycopeptide usage but an active antimicrobial management program, data were prospectively evaluated for 1995 to 2000 to assess the variation of glycopeptide use over time. ...Active antimicrobial management in one of the hosp …
At one of the hospitals with comparatively low glycopeptide usage but an active antimicrobial management program, data were prospecti …
Update on glycopeptide use in german university hospitals.
Kern WV, De With K, Gonnermann C, Strehl E, Bergner J, Höffken G, Dörje F, Daschner F, Steib-Bauert M, Haber M, Herrmann M, Hartmann M, Straube E, Bühner R, Rothe U, Salzberger B, Marre R, Kern P; Medical Antibiotic Use Surveillance and Evaluation. Kern WV, et al. Infection. 2004 Jun;32(3):157-62. doi: 10.1007/s15010-004-3159-0. Infection. 2004. PMID: 15188076

Active antimicrobial management in one of the hospitals was associated with the containment of glycopeptide consumption in the medical and surgical service at < 1.5 defined daily doses (DDD)/100 patient days in the subsequent period. ...CONCLUSION: These recent data fro

Active antimicrobial management in one of the hospitals was associated with the containment of glycopeptide consumption in the medica …
[Antibiotic Use at German University Hospitals (Project INTERUNI-II). Results for Medical Intensive Care, Hematology-Oncology, and Other Medical Service Areas].
de With K, Bergner J, Bühner R, Dörje F, Gonnermann C, Haber M, Hartmann M, Rothe U, Strehl E, Steib-Bauert M, Kern WV. de With K, et al. Med Klin (Munich). 2004 Jul 15;99(7):347-54. doi: 10.1007/s00063-004-1052-3. Med Klin (Munich). 2004. PMID: 15322713 German.
The definition of prescribed daily doses was according to guidelines for antimicrobial therapy in adults with normal renal and hepatic function used in the participant hospitals. ...Given the variation in the obtained estimates, targeted prospective hospital antibiotic use …
The definition of prescribed daily doses was according to guidelines for antimicrobial therapy in adults with normal renal and hepati …
Antibiotic use in German university hospitals 1998-2000 (Project INTERUNI-II).
de With K, Bergner J, Bühner R, Dörje F, Gonnermann C, Haber M, Hartmann M, Rothe U, Strehl E, Steib-Bauert M, Kern WV. de With K, et al. Int J Antimicrob Agents. 2004 Sep;24(3):213-8. doi: 10.1016/j.ijantimicag.2004.03.015. Int J Antimicrob Agents. 2004. PMID: 15325423 Clinical Trial.
Antibiotic use in Germany and European comparison.
De With K, Schröder H, Meyer E, Nink K, Hoffmann S, Steib-Bauert M, Kämmerer R, Ruess S, Daschner FD, Kern WV. De With K, et al. Dtsch Med Wochenschr. 2004 Sep 17;129(38):1987-92. doi: 10.1055/s-2004-831838. Dtsch Med Wochenschr. 2004. PMID: 15375742 Review.
This information allows estimation of antibiotic use in ambulatory and hospital care as compared with to other EU countries. ...
This information allows estimation of antibiotic use in ambulatory and hospital care as compared with to other EU countries. ...
Antibiotic use in non-university regional acute care general hospitals in southwestern Germany, 2001-2002.
Kern WV, de With K, Steib-Bauert M, Fellhauer M, Plangger A, Probst W; MABUSE-INTERREGIO-II Project Team. Kern WV, et al. Infection. 2005 Oct;33(5-6):333-9. doi: 10.1007/s15010-005-5059-3. Infection. 2005. PMID: 16258863
Use density in internal medicine (ICU areas excluded) in the year 2002 ranged between 13.5 and 93.7 DDD/100 with a weighted mean of 49.9 DDD/100 (corresponding to 28.6 PDD/100, respectively). Values for surgery were lower with a weighted mean of 43.4 DDD/100 (corres …
Use density in internal medicine (ICU areas excluded) in the year 2002 ranged between 13.5 and 93.7 DDD/100 with a weighted mean of 4 …
Trends in antibiotic use at a university hospital: defined or prescribed daily doses? Patient days or admissions as denominator?
de With K, Maier L, Steib-Bauert M, Kern P, Kern WV. de With K, et al. Infection. 2006 Apr;34(2):91-4. doi: 10.1007/s15010-006-5085-9. Infection. 2006. PMID: 16703299
A PDD dose definition (prescribed daily doses), defining doses that reflect the usually prescribed dose in adult hospitalized patients with normal renal function was compared with the WHO/ATC 2001 DDD dose definitions. ...RESULTS AND CONCLUSION: The DDD/100 patient …
A PDD dose definition (prescribed daily doses), defining doses that reflect the usually prescribed dose in adult hospitalized patients wi
Antibiotic use in two cohorts of German intensive care units.
de With K, Meyer E, Steib-Bauert M, Schwab F, Daschner FD, Kern WV. de With K, et al. J Hosp Infect. 2006 Nov;64(3):231-7. doi: 10.1016/j.jhin.2006.05.018. Epub 2006 Aug 7. J Hosp Infect. 2006. PMID: 16891039 Clinical Trial.
One cohort included ICUs participating in a surveillance programme (N=34) collecting antibiotic use and bacterial resistance data, with quarterly feedback. ...High use of antibiotics was primarily associated with hospital affiliation (university vs non-university) a …
One cohort included ICUs participating in a surveillance programme (N=34) collecting antibiotic use and bacterial resistance data, with
Regional variation in outpatient antibiotic prescribing in Germany.
Kern WV, de With K, Nink K, Steib-Bauert M, Schröder H. Kern WV, et al. Infection. 2006 Oct;34(5):269-73. doi: 10.1007/s15010-006-6618-y. Infection. 2006. PMID: 17033751
Penicillins were the most frequent prescribed drugs, but their use density showed a relatively large regional variation (factor 3.5), with relatively low prescription frequency in the eastern states. ...
Penicillins were the most frequent prescribed drugs, but their use density showed a relatively large regional variation (factor 3.5), wit
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