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101 results

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BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
Gorombei P, Guidez F, Ganesan S, Chiquet M, Pellagatti A, Goursaud L, Tekin N, Beurlet S, Patel S, Guerenne L, Le Pogam C, Setterblad N, de la Grange P, LeBoeuf C, Janin A, Noguera ME, Sarda-Mantel L, Merlet P, Boultwood J, Konopleva M, Andreeff M, West R, Pla M, Adès L, Fenaux P, Krief P, Chomienne C, Omidvar N, Padua RA. Gorombei P, et al. Among authors: de la grange p. Int J Mol Sci. 2021 Sep 30;22(19):10658. doi: 10.3390/ijms221910658. Int J Mol Sci. 2021. PMID: 34638998 Free PMC article.
Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis.
Gandoura S, Weiss E, Rautou PE, Fasseu M, Gustot T, Lemoine F, Hurtado-Nedelec M, Hego C, Vadrot N, Elkrief L, Lettéron P, Tellier Z, Pocidalo MA, Valla D, Lebrec D, Groyer A, Monteiro RC, de la Grange P, Moreau R. Gandoura S, et al. Among authors: de la grange p. J Hepatol. 2013 May;58(5):936-48. doi: 10.1016/j.jhep.2012.12.025. Epub 2013 Jan 12. J Hepatol. 2013. PMID: 23321315
BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.
Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, de la Grange P, Leboeuf C, Janin A, Noguera ME, Hervatin F, Sarda-Mantel L, Konopleva M, Andreeff M, Tu AW, Fan AC, Felsher DW, Whetton A, Pla M, West R, Fenaux P, Chomienne C, Padua RA. Beurlet S, et al. Among authors: de la grange p. Blood. 2013 Oct 17;122(16):2864-76. doi: 10.1182/blood-2012-07-445635. Epub 2013 Aug 13. Blood. 2013. PMID: 23943652 Free PMC article.
Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.
Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, Clay D, Guimiot F, Sanfilippo S, Jacques S, de la Grange P, Robil N, Soulier J, Souyri M. Domenech C, et al. Among authors: de la grange p. Stem Cell Reports. 2018 Nov 13;11(5):1075-1091. doi: 10.1016/j.stemcr.2018.10.001. Epub 2018 Oct 25. Stem Cell Reports. 2018. PMID: 30449320 Free PMC article.
Splicing factor and exon profiling across human tissues.
de la Grange P, Gratadou L, Delord M, Dutertre M, Auboeuf D. de la Grange P, et al. Nucleic Acids Res. 2010 May;38(9):2825-38. doi: 10.1093/nar/gkq008. Epub 2010 Jan 27. Nucleic Acids Res. 2010. PMID: 20110256 Free PMC article.
101 results