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Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.
Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM, Pedroza-Pacheco I, Waithe D, de la Serna JB, Lagerholm BC, Liu TL, Chew TL, Betzig E, Davis SJ, Eggeling C. Fritzsche M, et al. Among authors: de la serna jb. Sci Adv. 2017 Jun 21;3(6):e1603032. doi: 10.1126/sciadv.1603032. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28691087 Free PMC article.
Orchestrated control of filaggrin-actin scaffolds underpins cornification.
Gutowska-Owsiak D, de La Serna JB, Fritzsche M, Naeem A, Podobas EI, Leeming M, Colin-York H, O'Shaughnessy R, Eggeling C, Ogg GS. Gutowska-Owsiak D, et al. Among authors: de la serna jb. Cell Death Dis. 2018 Apr 1;9(4):412. doi: 10.1038/s41419-018-0407-2. Cell Death Dis. 2018. PMID: 29545605 Free PMC article.
Capturing resting T cells: the perils of PLL.
Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF. Santos AM, et al. Among authors: de la serna jb. Nat Immunol. 2018 Mar;19(3):203-205. doi: 10.1038/s41590-018-0048-8. Epub 2018 Feb 23. Nat Immunol. 2018. PMID: 29476188 Free PMC article. No abstract available.
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G. Jarrett R, et al. Among authors: de la serna jb. Sci Transl Med. 2016 Feb 10;8(325):325ra18. doi: 10.1126/scitranslmed.aad6833. Sci Transl Med. 2016. PMID: 26865566 Free PMC article.
Excess filaggrin in keratinocytes is removed by extracellular vesicles to prevent premature death and this mechanism can be hijacked by Staphylococcus aureus in a TLR2-dependent fashion.
Kobiela A, Hovhannisyan L, Jurkowska P, de la Serna JB, Bogucka A, Deptuła M, Paul AA, Panek K, Czechowska E, Rychłowski M, Królicka A, Zieliński J, Gabrielsson S, Pikuła M, Trzeciak M, Ogg GS, Gutowska-Owsiak D. Kobiela A, et al. Among authors: de la serna jb. J Extracell Vesicles. 2023 Jun;12(6):e12335. doi: 10.1002/jev2.12335. J Extracell Vesicles. 2023. PMID: 37338870 Free PMC article.
Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial.
Dushianthan A, Clark H, Madsen J, Mogg R, Matthews L, Berry L, de la Serna JB, Batchelor J, Brealey D, Hussell T, Porter J, Djukanovic R, Feelisch M, Postle A, Grocott MPW. Dushianthan A, et al. Among authors: de la serna jb. Trials. 2020 Dec 10;21(1):1014. doi: 10.1186/s13063-020-04944-5. Trials. 2020. PMID: 33302976 Free PMC article. Clinical Trial.