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Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases.
Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT. Dayalan Naidu S, et al. Among authors: de la vega l. Mol Cell Biol. 2016 Aug 26;36(18):2403-17. doi: 10.1128/MCB.00292-16. Print 2016 Sep 15. Mol Cell Biol. 2016. PMID: 27354066 Free PMC article.
Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses.
Torrente L, Sanchez C, Moreno R, Chowdhry S, Cabello P, Isono K, Koseki H, Honda T, Hayes JD, Dinkova-Kostova AT, de la Vega L. Torrente L, et al. Among authors: de la vega l. Oncogene. 2017 Nov 2;36(44):6204-6212. doi: 10.1038/onc.2017.221. Epub 2017 Jul 10. Oncogene. 2017. PMID: 28692050 Free PMC article.
Transcription factors NRF2 and HSF1 have opposing functions in autophagy.
Dayalan Naidu S, Dikovskaya D, Gaurilcikaite E, Knatko EV, Healy ZR, Mohan H, Koh G, Laurell A, Ball G, Olagnier D, de la Vega L, Ganley IG, Talalay P, Dinkova-Kostova AT. Dayalan Naidu S, et al. Among authors: de la vega l. Sci Rep. 2017 Sep 8;7(1):11023. doi: 10.1038/s41598-017-11262-5. Sci Rep. 2017. PMID: 28887499 Free PMC article.
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity.
Casares L, Unciti-Broceta JD, Prados ME, Caprioglio D, Mattoteia D, Higgins M, Apendino G, Dinkova-Kostova AT, Muñoz E, de la Vega L. Casares L, et al. Among authors: de la vega l. Redox Biol. 2020 Oct;37:101689. doi: 10.1016/j.redox.2020.101689. Epub 2020 Aug 22. Redox Biol. 2020. PMID: 32863231 Free PMC article.
High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro.
Torrente L, Maan G, Oumkaltoum Rezig A, Quinn J, Jackson A, Grilli A, Casares L, Zhang Y, Kulesskiy E, Saarela J, Bicciato S, Edwards J, Dinkova-Kostova AT, de la Vega L. Torrente L, et al. Among authors: de la vega l. Biomolecules. 2020 Sep 25;10(10):1365. doi: 10.3390/biom10101365. Biomolecules. 2020. PMID: 32992842 Free PMC article.
Downregulation of Keap1 Confers Features of a Fasted Metabolic State.
Knatko EV, Tatham MH, Zhang Y, Castro C, Higgins M, Dayalan Naidu S, Leonardi C, de la Vega L, Honda T, Griffin JL, Hay RT, Dinkova-Kostova AT. Knatko EV, et al. Among authors: de la vega l. iScience. 2020 Oct 6;23(10):101638. doi: 10.1016/j.isci.2020.101638. eCollection 2020 Oct 23. iScience. 2020. PMID: 33103077 Free PMC article.
Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors.
Zhang Y, Knatko EV, Higgins M, Dayalan Naidu S, Smith G, Honda T, de la Vega L, Dinkova-Kostova AT. Zhang Y, et al. Among authors: de la vega l. Antioxidants (Basel). 2022 Jan 28;11(2):262. doi: 10.3390/antiox11020262. Antioxidants (Basel). 2022. PMID: 35204145 Free PMC article.
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity.
Casares L, Moreno R, Ali KX, Higgins M, Dayalan Naidu S, Neill G, Cassin L, Kiib AE, Svenningsen EB, Minassi A, Honda T, Poulsen TB, Wiel C, Sayin VI, Dinkova-Kostova AT, Olagnier D, de la Vega L. Casares L, et al. Among authors: de la vega l. Redox Biol. 2022 May;51:102291. doi: 10.1016/j.redox.2022.102291. Epub 2022 Mar 17. Redox Biol. 2022. PMID: 35313207 Free PMC article.
58 results