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Year Number of Results
1994 2
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93 results

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Page 1
Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.
Reichert CF, Deboer T, Landolt HP. Reichert CF, et al. Among authors: deboer t. J Sleep Res. 2022 Aug;31(4):e13597. doi: 10.1111/jsr.13597. Epub 2022 May 16. J Sleep Res. 2022. PMID: 35575450 Free PMC article. Review.
Since the scientific demonstration that this is indeed the case, progress has been fast. Today, adenosine is widely accepted as an endogenous sleep-regulatory substance. In this review, we discuss the current state of the science in model organisms and humans on the …
Since the scientific demonstration that this is indeed the case, progress has been fast. Today, adenosine is widely accepted as an en …
The two-process model of sleep regulation: a reappraisal.
Borbély AA, Daan S, Wirz-Justice A, Deboer T. Borbély AA, et al. Among authors: deboer t. J Sleep Res. 2016 Apr;25(2):131-43. doi: 10.1111/jsr.12371. Epub 2016 Jan 14. J Sleep Res. 2016. PMID: 26762182 Free article.
A deficiency of Process S was proposed to account for both depressive sleep disturbances and the antidepressant effect of sleep deprivation. The model supported the development of novel non-pharmacological treatment paradigms in psychiatry, based on manipulating …
A deficiency of Process S was proposed to account for both depressive sleep disturbances and the antidepressant effect of sleep …
The aging brain: sleep, the circadian clock and exercise.
Panagiotou M, Michel S, Meijer JH, Deboer T. Panagiotou M, et al. Among authors: deboer t. Biochem Pharmacol. 2021 Sep;191:114563. doi: 10.1016/j.bcp.2021.114563. Epub 2021 Apr 19. Biochem Pharmacol. 2021. PMID: 33857490 Free article. Review.
In our review, we focus on the morphological and functional alterations that the aging brain undergoes affecting sleep and the circadian clock in both human and rodent models. Although both species share mammalian features, differences have been identified on severa …
In our review, we focus on the morphological and functional alterations that the aging brain undergoes affecting sleep and the cir …
Behavioral and electrophysiological correlates of sleep and sleep homeostasis.
Deboer T. Deboer T. Curr Top Behav Neurosci. 2015;25:1-24. doi: 10.1007/7854_2013_248. Curr Top Behav Neurosci. 2015. PMID: 24142866 Review.
In mammals and birds, sleep is generally subdivided into two states, non-rapid eye movement (NREM) sleep and REM sleep. ...Incorporating local sleep into models of sleep regulation is needed to obtain a comprehensive picture....
In mammals and birds, sleep is generally subdivided into two states, non-rapid eye movement (NREM) sleep and REM sleep. …
Sleep Deprivation Does not Change the Flash Electroretinogram in Wild-type and Opn4(-/-)Gnat1(-/-) Mice.
Schoonderwoerd RA, Buck TM, Andriessen CA, Wijnholds J, Hattar S, Meijer JH, Deboer T. Schoonderwoerd RA, et al. Among authors: deboer t. J Biol Rhythms. 2022 Apr;37(2):216-221. doi: 10.1177/07487304221074995. Epub 2022 Feb 8. J Biol Rhythms. 2022. PMID: 35132885 Free PMC article.
Sleep deprivation reduces the response of neuronal activity in the suprachiasmatic nucleus (SCN) and the phase shift in circadian behaviour to phase shifting light pulses, and thus seems to impair the adaptation of the circadian clock to the external light-da …
Sleep deprivation reduces the response of neuronal activity in the suprachiasmatic nucleus (SCN) and the phase shift in circadian …
Sleep homeostasis and the circadian clock: Do the circadian pacemaker and the sleep homeostat influence each other's functioning?
Deboer T. Deboer T. Neurobiol Sleep Circadian Rhythms. 2018 Mar 1;5:68-77. doi: 10.1016/j.nbscr.2018.02.003. eCollection 2018 Jun. Neurobiol Sleep Circadian Rhythms. 2018. PMID: 31236513 Free PMC article. Review.
Sleep is regulated by a homeostatic and a circadian process. Together these two processes determine most aspects of sleep and related variables like sleepiness and alertness. ...The strongest evidence of an influence of sleep homeostatic mechanisms on …
Sleep is regulated by a homeostatic and a circadian process. Together these two processes determine most aspects of sleep …
Aging of the suprachiasmatic clock.
Farajnia S, Deboer T, Rohling JH, Meijer JH, Michel S. Farajnia S, et al. Among authors: deboer t. Neuroscientist. 2014 Feb;20(1):44-55. doi: 10.1177/1073858413498936. Epub 2013 Aug 7. Neuroscientist. 2014. PMID: 23924666 Review.
More than half of the elderly in today's society suffer from sleep disorders with detrimental effects on brain function, behavior, and social life. A major contribution to the regulation of sleep stems from the circadian system. The central circadian c …
More than half of the elderly in today's society suffer from sleep disorders with detrimental effects on brain function, behavior, an …
Sleep and the sleep electroencephalogram in C57BL/6 and C3H/HeN mice.
van Dorp R, Rolleri E, Deboer T. van Dorp R, et al. Among authors: deboer t. J Sleep Res. 2024 Apr;33(2):e14062. doi: 10.1111/jsr.14062. Epub 2023 Oct 6. J Sleep Res. 2024. PMID: 37803888
The C3H mice spent more time in NREM sleep around the light-dark transition and more time in REM sleep during the dark phase compared with C57bl/6 mice. ...We conclude that differences between mouse strains should be considered when selecting a model strain to impro …
The C3H mice spent more time in NREM sleep around the light-dark transition and more time in REM sleep during the dark phase c …
Internal circadian misallignment in a mouse model of chemotherapy induced fatigue.
Wang Y, van Beurden AW, Tersteeg MMH, Michel S, Kastelein A, Neefjes J, Rohling JHT, Meijer JH, Deboer T. Wang Y, et al. Among authors: deboer t. Brain Behav Immun. 2024 Jan;115:588-599. doi: 10.1016/j.bbi.2023.11.020. Epub 2023 Nov 19. Brain Behav Immun. 2024. PMID: 37984623 Free article.
Previously we have shown in a mouse model of cancer related fatigue that doxorubicin treatment induces fatigue-like symptoms related to disturbed circadian rhythms. However, the specific components of the circadian regulatory circuitry affected by doxorubicin treatm …
Previously we have shown in a mouse model of cancer related fatigue that doxorubicin treatment induces fatigue-like symptoms related to dist …
Circadian modulation of sleep in rodents.
Yasenkov R, Deboer T. Yasenkov R, et al. Among authors: deboer t. Prog Brain Res. 2012;199:203-218. doi: 10.1016/B978-0-444-59427-3.00012-5. Prog Brain Res. 2012. PMID: 22877667 Review.
Sleep is regulated by circadian and homeostatic processes. The sleep homeostat keeps track of the duration of prior sleep and waking and determines the intensity of sleep. ...Therefore, in the rat, the sleep homeostatic modulation in phas …
Sleep is regulated by circadian and homeostatic processes. The sleep homeostat keeps track of the duration of prior …
93 results