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Year Number of Results
1975 1
1981 2
1986 1
1987 1
1988 1
1989 1
1990 1
1992 1
2001 2
2005 3
2006 1
2009 1
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2013 1
2017 1
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21 results

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Page 1
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications.
Carotti A, Ianni F, Camaioni E, Pucciarini L, Marinozzi M, Sardella R, Natalini B. Carotti A, et al. J Pharm Biomed Anal. 2017 Sep 10;144:31-40. doi: 10.1016/j.jpba.2017.02.009. Epub 2017 Feb 5. J Pharm Biomed Anal. 2017. PMID: 28209350
In search for new enantioselectivity profiles, the N-decyl-S-trityl-(R)-cysteine [C(10)-(R)-STC] was synthesized through a one-step procedure and then hydrophobically adsorbed onto an octadecylsilica surface to generate a stable chiral stationary phase for ligand-exchange …
In search for new enantioselectivity profiles, the N-decyl-S-trityl-(R)-cysteine [C(10)-(R)-STC] was synthesized through a one-step p …
Substituted Cysteine Modification and Protection with n-Alkyl- Methanethiosulfonate Reagents Yields a Precise Estimate of the Distance between Etomidate and a Residue in Activated GABA Type A Receptors.
Fantasia RJ, Nourmahnad A, Halpin E, Forman SA. Fantasia RJ, et al. Mol Pharmacol. 2021 Jun;99(6):426-434. doi: 10.1124/molpharm.120.000224. Epub 2021 Mar 25. Mol Pharmacol. 2021. PMID: 33766924 Free PMC article.
Using voltage-clamp electrophysiology in Xenopus oocytes expressing alpha1beta3M286Cgamma2L GABA(A) receptors, we measured functional changes after exposing GABA-activated receptors to n-alkyl-MTS reagents, from methyl-MTS to n-decyl-MTS. Based on previous studies using a …
Using voltage-clamp electrophysiology in Xenopus oocytes expressing alpha1beta3M286Cgamma2L GABA(A) receptors, we measured functional change …
Substituted Cysteine Modification and Protection with n-Alkyl-MTS Reagents Quantifies Steric Changes Induced by a Mutation in Anesthetic Binding Sites on GABA Type A Receptors.
Bhave K, Forman SA. Bhave K, et al. Mol Pharmacol. 2023 Dec;104(6):266-274. doi: 10.1124/molpharm.123.000719. Epub 2023 Aug 16. Mol Pharmacol. 2023. PMID: 37586749
Voltage-clamp electrophysiology in Xenopus oocytes was used to assess persistent functional changes after exposing cysteine-substituted receptors to methyl-MTS through n-decyl-MTS. Overlap of modified cysteine sidechains with bound anesthetic was inferred when anesthetic c …
Voltage-clamp electrophysiology in Xenopus oocytes was used to assess persistent functional changes after exposing cysteine-substituted rece …
Structure-antitumor activity relationship of purin-6-yl alkyl disulfides.
Inomata M, Fukuoka F, Hoshi A, Kuretani K, Saneyoshi M. Inomata M, et al. J Pharmacobiodyn. 1981 Jan;4(1):58-64. doi: 10.1248/bpb1978.4.58. J Pharmacobiodyn. 1981. PMID: 7196946
Most disulfide derivatives of 6-MP and 6-TG showed higher antitumor activity (lower ED50) and higher toxicity to host (lower LD50) than parent compounds, but ratios of increase in activity and toxicity were different with each other. The compounds with higher chemot …
Most disulfide derivatives of 6-MP and 6-TG showed higher antitumor activity (lower ED50) and higher toxicity to host (lower LD50) than pare …
Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification.
Torchilin VP, Levchenko TS, Whiteman KR, Yaroslavov AA, Tsatsakis AM, Rizos AK, Michailova EV, Shtilman MI. Torchilin VP, et al. Biomaterials. 2001 Nov;22(22):3035-44. doi: 10.1016/s0142-9612(01)00050-3. Biomaterials. 2001. PMID: 11575478
To prepare amphiphilic PVP with the end stearyl (S) or palmityl (P) residues, amino- and carboxy-terminated PVP derivatives were first synthesized by the free-radical polymerization of vinyl pyrrolidone in the presence of amino- or carboxy-mercaptans as chain transfer agen …
To prepare amphiphilic PVP with the end stearyl (S) or palmityl (P) residues, amino- and carboxy-terminated PVP derivatives were first synth …
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.
Bäck M, Kumlin M, Cotgreave IA, Dahlén SE. Bäck M, et al. Br J Pharmacol. 2001 Aug;133(7):1134-44. doi: 10.1038/sj.bjp.0704180. Br J Pharmacol. 2001. PMID: 11487525 Free PMC article.
This qualitative change of the LTD(4)-induced contraction was also observed in the presence of S-decyl GSH (100 microM), GSH (10 mM) and GSSG (10 mM). S-hexyl GSH, S-decyl GSH, GSH and GSSG all stimulated a formation of [(3)H]-LTC(4) from [(3)H]-LTD(4). In conclusio …
This qualitative change of the LTD(4)-induced contraction was also observed in the presence of S-decyl GSH (100 microM), GSH (10 mM) …
Inhibition of soybean lipoxygenase-1 by n-alcohols and n-alkylthiols.
Kuninori T, Nishiyama J, Shirakawa M, Shimoyama A. Kuninori T, et al. Biochim Biophys Acta. 1992 Apr 8;1125(1):49-55. doi: 10.1016/0005-2760(92)90154-n. Biochim Biophys Acta. 1992. PMID: 1567907
From the behavior of pKi dependence on the carbon number of the alcohol, the decyl group appears to be optimum to bind to L-1. The thermodynamic analysis for the inhibition based upon van 't Hoff equation indicates positive enthalpy and entropy changes for the binding of t …
From the behavior of pKi dependence on the carbon number of the alcohol, the decyl group appears to be optimum to bind to L-1. The th …
SAMs on gold derived from the direct adsorption of alkanethioacetates are inferior to those derived from the direct adsorption of alkanethiols.
Béthencourt MI, Srisombat LO, Chinwangso P, Lee TR. Béthencourt MI, et al. Langmuir. 2009 Feb 3;25(3):1265-71. doi: 10.1021/la803179q. Langmuir. 2009. PMID: 19123812
Self-assembled monolayers (SAMs) on gold derived from the direct adsorption of thioacetic acid S-decyl ester (C10SAc) and thioacetic acid S-octadecyl ester (C18SAc) were compared to the corresponding SAMs derived from the analogous adsorption n-decanethiol (C10SH) and n-oc …
Self-assembled monolayers (SAMs) on gold derived from the direct adsorption of thioacetic acid S-decyl ester (C10SAc) and thioacetic …
The effect of ring substituents on the mechanism of interaction of exogenous quinones with the mitochondrial respiratory chain.
Chen M, Liu BL, Gu LQ, Zhu QS. Chen M, et al. Biochim Biophys Acta. 1986 Oct 8;851(3):469-74. doi: 10.1016/0005-2728(86)90083-6. Biochim Biophys Acta. 1986. PMID: 3019395
It is concluded that quinones with a ubiquinone ring can be reduced directly by succinate:Q reductase, whereas those with a plastoquinone ring can not. Reduction of the latter compounds requires participation of either center i or center o (Mitchell, P. (1975) FEBS Lett. 5 …
It is concluded that quinones with a ubiquinone ring can be reduced directly by succinate:Q reductase, whereas those with a plastoquinone ri …
21 results