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Interleukin 1 affects glucose homeostasis.
del Rey A, Besedovsky H. del Rey A, et al. Am J Physiol. 1987 Nov;253(5 Pt 2):R794-8. doi: 10.1152/ajpregu.1987.253.5.R794. Am J Physiol. 1987. PMID: 3318508
Furthermore, these animals responded normally to a challenge with glucose, thus suggesting that the proper function of the pancreas was preserved. ...IL 1 administration to adrenalectomized rats resulted in a more marked hypoglycemia and in a profound hypoins …
Furthermore, these animals responded normally to a challenge with glucose, thus suggesting that the proper function of the pancreas w …
Host endocrine responses during tumor growth.
Besedovsky H, del Rey A, Normann SJ. Besedovsky H, et al. Among authors: del rey a. Prog Clin Biol Res. 1989;288:203-13. Prog Clin Biol Res. 1989. PMID: 2654951
Among the hormonal changes induced were a biphasic increase in the level of serum corticosterone, a biphasic decrease in serum insulin levels, an early decrease in prolactin and a terminal severe deficiency in thyroxine. ...First, a concordance was not …
Among the hormonal changes induced were a biphasic increase in the level of serum corticosterone, a biphasic decrease in serum …
Interleukin-1 and glucose homeostasis: an example of the biological relevance of immune-neuroendocrine interactions.
Besedovsky HO, del Rey A. Besedovsky HO, et al. Among authors: del rey a. Horm Res. 1989;31(1-2):94-9. doi: 10.1159/000181095. Horm Res. 1989. PMID: 2785952
Interleukin-1 (IL-1), a cytokine mainly produced by monocytes-macrophages, plays a crucial role in immunological and inflammatory processes. ...Furthermore, IL-1 seems to adjust the 'set point' for glucose regulation to a lower level. The effects of IL-1 on g …
Interleukin-1 (IL-1), a cytokine mainly produced by monocytes-macrophages, plays a crucial role in immunological and inflammat …
Interleukin-1 stimulates aldosterone secretion: involvement of renin, ACTH, and prostaglandins.
Bataillard A, del Rey A, Klusman I, Arditi GM, Besedovsky HO. Bataillard A, et al. Among authors: del rey a. Am J Physiol. 1992 Oct;263(4 Pt 2):R840-4. doi: 10.1152/ajpregu.1992.263.4.R840. Am J Physiol. 1992. PMID: 1329566
Interleukin-1 (IL-1), a cytokine produced during infection and inflammation, mediates some of the endocrinological alterations that parallel these processes. ...We observed that intravenous administration of hrIL-1 into conscious unrestrained rats elicited a marked …
Interleukin-1 (IL-1), a cytokine produced during infection and inflammation, mediates some of the endocrinological alterations that p …
Interleukin-1, but not stress, stimulates glucocorticoid output during early postnatal life in mice.
Furukawa H, del Rey A, Monge-Arditi G, Besedovsky HO. Furukawa H, et al. Among authors: del rey a. Ann N Y Acad Sci. 1998 May 1;840:117-22. doi: 10.1111/j.1749-6632.1998.tb09555.x. Ann N Y Acad Sci. 1998. PMID: 9629243
We have extended these studies and found that the glucocorticoid response elicited in 5-day-old mice by a low dose of IL-1 beta is not desensitized by previous exposure to the cytokine. ...Thus, IL-1 beta can elicit a corticosterone response during the postnatal str …
We have extended these studies and found that the glucocorticoid response elicited in 5-day-old mice by a low dose of IL-1 beta is no …
Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones.
Besedovsky H, del Rey A, Sorkin E, Dinarello CA. Besedovsky H, et al. Among authors: del rey a. Science. 1986 Aug 8;233(4764):652-4. doi: 10.1126/science.3014662. Science. 1986. PMID: 3014662
Interleukin-1 induces changes in norepinephrine metabolism in the rat brain.
Kabiersch A, del Rey A, Honegger CG, Besedovsky HO. Kabiersch A, et al. Among authors: del rey a. Brain Behav Immun. 1988 Sep;2(3):267-74. doi: 10.1016/0889-1591(88)90028-1. Brain Behav Immun. 1988. PMID: 3266560
Interleukin-1 (IL-1) is a hormone that, apart from playing a key role in immune and inflammatory processes, can also affect mechanisms under brain control. ...The capacity of IL-1 to affect the metabolism of NE, a neurotransmitter involved in the control of …
Interleukin-1 (IL-1) is a hormone that, apart from playing a key role in immune and inflammatory processes, can also affect me …
Neuroendocrine and metabolic responses induced by interleukin-1.
Besedovsky H, del Rey A. Besedovsky H, et al. Among authors: del rey a. J Neurosci Res. 1987;18(1):172-8. doi: 10.1002/jnr.490180124. J Neurosci Res. 1987. PMID: 2824799
We have previously demonstrated that Interleukin-1 (IL-1), a cytokine mainly produced by activated monocytes, stimulates the pituitary-adrenal axis and affects glucose homeostasis. ...A marked reduction in blood glucose levels occurred in these animals. This effect …
We have previously demonstrated that Interleukin-1 (IL-1), a cytokine mainly produced by activated monocytes, stimulates the pituitar …
Antidiabetic effects of interleukin 1.
del Rey A, Besedovsky H. del Rey A, et al. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5943-7. doi: 10.1073/pnas.86.15.5943. Proc Natl Acad Sci U S A. 1989. PMID: 2668949 Free PMC article.
In these animal models, a single injection of a low dose of human recombinant IL-1 normalized glucose blood levels for several hours. ...Although the final mechanism of action is at present unknown, the results showed that IL-1 is a hormone with powerful anti …
In these animal models, a single injection of a low dose of human recombinant IL-1 normalized glucose blood levels for several …
Mechanism of virus-induced stimulation of the hypothalamus-pituitary-adrenal axis.
Besedovsky HO, del Rey A. Besedovsky HO, et al. Among authors: del rey a. J Steroid Biochem. 1989;34(1-6):235-9. doi: 10.1016/0022-4731(89)90087-3. J Steroid Biochem. 1989. PMID: 2560513
In this paper, we report data obtained from a model in rodents showing that the pituitary-adrenal axis is stimulated following inoculation of Newcastle Disease Virus (NDV). ...
In this paper, we report data obtained from a model in rodents showing that the pituitary-adrenal axis is stimulated following inocul …
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