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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1967 1
1971 4
1972 1
1973 2
1976 2
1977 5
1978 1
1979 1
1980 2
1981 3
1982 2
1983 3
1984 1
1985 3
1986 8
1987 3
1988 4
1989 3
1990 6
1991 3
1992 1
1993 3
1994 3
1995 4
1996 2
1997 5
1998 6
1999 4
2000 4
2001 10
2002 8
2003 22
2004 19
2005 32
2006 49
2007 51
2008 63
2009 65
2010 74
2011 65
2012 56
2013 72
2014 56
2015 68
2016 70
2017 66
2018 65
2019 69
2020 61
2021 39
2022 30
2023 4
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1,055 results
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Page 1
Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancers.
Wakui M, Yokoyama Y, Wang H, Shigeto T, Futagami M, Mizunuma H. Wakui M, et al. J Cancer Res Clin Oncol. 2010 Aug;136(8):1143-50. doi: 10.1007/s00432-010-0761-7. Epub 2010 Jan 13. J Cancer Res Clin Oncol. 2010. PMID: 20069433
With an aim to apply PDT for intraperitoneal disseminated foci of advanced or recurrent ovarian cancers, the present study was conducted to evaluate the antitumor effect of PDT using a methyl ester of 5-aminolevulinic acid (Methyl-ALA) on variou …
With an aim to apply PDT for intraperitoneal disseminated foci of advanced or recurrent ovarian cancers, the present study was conducted to …
Topical methyl aminolevulinate.
Siddiqui MA, Perry CM, Scott LJ. Siddiqui MA, et al. Am J Clin Dermatol. 2004;5(2):127-37; discussion 138-40. doi: 10.2165/00128071-200405020-00006. Am J Clin Dermatol. 2004. PMID: 15109276 Review.
Methyl aminolevulinate (MAL), an ester of aminolevulinic acid, has been used effectively as a topical photosensitizing agent in the photodynamic therapy (PDT) of epidermal lesions such as actinic keratosis (AK) and basal cell carcinoma (BCC). ..
Methyl aminolevulinate (MAL), an ester of aminolevulinic acid, has been used effectively as a topical pho
Metvix (PhotoCure).
Gardlo K, Ruzicka T. Gardlo K, et al. Curr Opin Investig Drugs. 2002 Nov;3(11):1672-8. Curr Opin Investig Drugs. 2002. PMID: 12476972 Review.
Metvix is a photosensitive cream containing the methyl ester of 5-aminolevulinic acid, which has been developed and launched by PhotoCure in Sweden for the treatment of high-risk basal cell carcinoma and actinic keratosis....
Metvix is a photosensitive cream containing the methyl ester of 5-aminolevulinic acid, which has been developed …
Aminolevulinic acid and methyl aminolevulinate equally effective in topical photodynamic therapy for non-melanoma skin cancers.
Tarstedt M, Gillstedt M, Wennberg Larkö AM, Paoli J. Tarstedt M, et al. J Eur Acad Dermatol Venereol. 2016 Mar;30(3):420-3. doi: 10.1111/jdv.13558. Epub 2016 Feb 3. J Eur Acad Dermatol Venereol. 2016. PMID: 26841041
BACKGROUND: Topical photodynamic therapy (PDT) is an effective treatment for superficial non-melanoma skin cancers. Two prodrugs, 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL), are available for clinical use. ...
BACKGROUND: Topical photodynamic therapy (PDT) is an effective treatment for superficial non-melanoma skin cancers. Two prodrugs, 5-amino
δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones.
Novak B, Schulten R, Lübbert H. Novak B, et al. Naunyn Schmiedebergs Arch Pharmacol. 2011 Dec;384(6):583-602. doi: 10.1007/s00210-011-0683-1. Epub 2011 Sep 25. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21947250
Application of delta-aminolevulinic acid (ALA) or its methyl ester (MAL) onto cutaneous tumours increases intracellular Protoporphyrin IX (PpIX), serving as photosensitizer in photodynamic therapy (PDT). ...The pharmacological profile of ALA and …
Application of delta-aminolevulinic acid (ALA) or its methyl ester (MAL) onto cutaneous tumours increases …
The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate.
Ma L, Steindal AE, Juzeniene A, Iani V, Moan J. Ma L, et al. Photochem Photobiol Sci. 2006 Aug;5(8):755-9. doi: 10.1039/b603828j. Epub 2006 Jun 14. Photochem Photobiol Sci. 2006. PMID: 16886091
5-Aminolevulinic acid (ALA) or its derivative methyl 5-aminolevulinate (MAL) combined with folic acid was applied in nude mice bearing human colon adenocarcinoma. ...It was found that the porphyrin production after i.p injection of 200 mg kg(-1) …
5-Aminolevulinic acid (ALA) or its derivative methyl 5-aminolevulinate (MAL) combined with folic acid was …
Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells.
Pye A, Curnow A. Pye A, et al. Photochem Photobiol. 2007 May-Jun;83(3):766-73. doi: 10.1562/2006-05-30-RA-906. Photochem Photobiol. 2007. PMID: 17576385
Aminolevulinic acid photodynamic therapy (ALA-PDT) is a cancer therapy that combines the selective accumulation of a photosensitizer in tumor tissue with visible light (and tissue oxygen) to produce reactive oxygen species. ...This study compares directly for the fi
Aminolevulinic acid photodynamic therapy (ALA-PDT) is a cancer therapy that combines the selective accumulation of a photosens
Induction of protoporphyrin IX in patient-derived synoviocytes, cartilage explants and chondrons after application of 5-aminolevulinic acid or its methyl ester.
Rudys R, Denkovskij J, Kirdaitė G, Bagdonas S. Rudys R, et al. J Photochem Photobiol B. 2014 Dec;141:228-34. doi: 10.1016/j.jphotobiol.2014.10.003. Epub 2014 Oct 17. J Photochem Photobiol B. 2014. PMID: 25463671
OBJECTIVE: To compare the accumulation of protoporphyrin IX between synoviocytes of patients with rheumatoid arthritis (RA) or osteoarthritis (OA) and cartilage explants (CE) as well as chondrons of patients with OA after the application of 5-aminolevulinic acid (AL …
OBJECTIVE: To compare the accumulation of protoporphyrin IX between synoviocytes of patients with rheumatoid arthritis (RA) or osteoarthriti …
Photodynamic therapy for aesthetic-cosmetic indications.
Philipp-Dormston WG. Philipp-Dormston WG. G Ital Dermatol Venereol. 2018 Dec;153(6):817-826. doi: 10.23736/S0392-0488.18.05982-5. Epub 2018 Mar 29. G Ital Dermatol Venereol. 2018. PMID: 29600693 Review.
The most widely studied topical sensitizers used in PDT are 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL). A range of pre-treatment procedures help improve skin absorption of the photosensitizer and lead to significantly improved efficac …
The most widely studied topical sensitizers used in PDT are 5-aminolevulinic acid (ALA) and methyl aminolevulinate
1,055 results