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Filters applied: . Clear all The following term was not found in PubMed: defitito
Page 1
Denileukin Diftitox.
[No authors listed] [No authors listed] 2017 Dec 27. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 2012–. PMID: 31643755 Free Books & Documents. Review.
Denileukin diftitox is a recombinant fusion protein of human interleukin-2 (IL-2) attached to diphtheria toxin fragments A and B that is used as an antineoplastic agent to treat cutaneous T cell lymphomas that express IL-2 receptors. High doses of denileukin diftito
Denileukin diftitox is a recombinant fusion protein of human interleukin-2 (IL-2) attached to diphtheria toxin fragments A and B that
Denileukin diftitox.
Figgitt DP, Lamb HM, Goa KL. Figgitt DP, et al. Am J Clin Dermatol. 2000 Jan-Feb;1(1):67-72; discussion 73. doi: 10.2165/00128071-200001010-00008. Am J Clin Dermatol. 2000. PMID: 11702307 Review.
Denileukin diftitox is a novel interleukin-2 receptor (IL-2R)-targeted diphtheria toxin. ...Vascular leak syndrome has occurred during denileukin diftitox therapy. Antibody titers to denileukin diftitox occur in most patients after treatment but the presence
Denileukin diftitox is a novel interleukin-2 receptor (IL-2R)-targeted diphtheria toxin. ...Vascular leak syndrome has occurred durin
Denileukin Diftitox.
[No authors listed] [No authors listed] 2020 Dec 21. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Drugs and Lactation Database (LactMed). 2006–. PMID: 33355734 Free Books & Documents. Review.
Novel and Future Therapeutic Drugs for Advanced Mycosis Fungoides and Sézary Syndrome.
Oka T, Miyagaki T. Oka T, et al. Front Med (Lausanne). 2019 May 29;6:116. doi: 10.3389/fmed.2019.00116. eCollection 2019. Front Med (Lausanne). 2019. PMID: 31192214 Free PMC article. Review.
These include mogamulizumab, brentuximab vedotin, alemtuzumab, immune checkpoint inhibitors, IPH4102 (anti-KIR3DL2 antibody), histone deacetylase inhibitors (vorinostat, romidepsin, panobinostat, belinostat, and resminostat), pralatrexate, forodesine, denileukin diftitox, …
These include mogamulizumab, brentuximab vedotin, alemtuzumab, immune checkpoint inhibitors, IPH4102 (anti-KIR3DL2 antibody), histone deacet …
Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus.
Dorhoi A, Kotzé LA, Berzofsky JA, Sui Y, Gabrilovich DI, Garg A, Hafner R, Khader SA, Schaible UE, Kaufmann SH, Walzl G, Lutz MB, Mahon RN, Ostrand-Rosenberg S, Bishai W, du Plessis N. Dorhoi A, et al. J Clin Invest. 2020 Jun 1;130(6):2789-2799. doi: 10.1172/JCI136288. J Clin Invest. 2020. PMID: 32420917 Free article. Review.
Denileukin diftitox: a novel immunotoxin.
Manoukian G, Hagemeister F. Manoukian G, et al. Expert Opin Biol Ther. 2009 Nov;9(11):1445-51. doi: 10.1517/14712590903348135. Expert Opin Biol Ther. 2009. PMID: 19817678 Review.
OBJECTIVE: To review FDA approved and other potential uses of Ontak, denileukin diftitox. METHODS: Information was obtained via the internet and a journal literature review. ...CONCLUSION: There are many potential uses for denileukin diftitox, in both malignant and …
OBJECTIVE: To review FDA approved and other potential uses of Ontak, denileukin diftitox. METHODS: Information was obtained via the i …
Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.
Luke JJ, Zha Y, Matijevich K, Gajewski TF. Luke JJ, et al. J Immunother Cancer. 2016 Jun 21;4:35. doi: 10.1186/s40425-016-0140-2. eCollection 2016. J Immunother Cancer. 2016. PMID: 27330808 Free PMC article.
Prior clinical trials of denileukin diftitox suggested reduction of FoxP3(+) Tregs and some clinical responses. METHOD: To investigate the immunologic effects of denileukin difitox on vaccine-specific immune responses in melanoma, a randomized clinical trial of sing …
Prior clinical trials of denileukin diftitox suggested reduction of FoxP3(+) Tregs and some clinical responses. METHOD: To investigat …
Denileukin diftitox: a concise clinical review.
Eklund JW, Kuzel TM. Eklund JW, et al. Expert Rev Anticancer Ther. 2005 Feb;5(1):33-8. doi: 10.1586/14737140.5.1.33. Expert Rev Anticancer Ther. 2005. PMID: 15757436 Review.
Denileukin diftitox (DAB389IL-2; Ontak) is a novel recombinant fusion protein approved by the US Food and Drug Administration for the treatment of relapsed or refractory cutaneous T-cell lymphoma. ...This article will review the clinical trials leading to the approval of
Denileukin diftitox (DAB389IL-2; Ontak) is a novel recombinant fusion protein approved by the US Food and Drug Administration for the
Optimizing denileukin diftitox (Ontak) therapy.
Duvic M, Talpur R. Duvic M, et al. Future Oncol. 2008 Aug;4(4):457-69. doi: 10.2217/14796694.4.4.457. Future Oncol. 2008. PMID: 18684057 Review.
Denileukin diftitox (Ontak) is a novel recombinant fusion protein consisting of peptide sequences for the enzymatically active and membrane translocation domain of diphtheria toxin linked to human IL-2. Denileukin diftitox specifically binds to IL-2 receptors on the
Denileukin diftitox (Ontak) is a novel recombinant fusion protein consisting of peptide sequences for the enzymatically active and me
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