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Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Reservoir.
Hensel MT, Marshall JD, Dorwart MR, Heeke DS, Rao E, Tummala P, Yu L, Cohen GH, Eisenberg RJ, Sloan DD. Hensel MT, et al. J Virol. 2017 Apr 13;91(9):e02257-16. doi: 10.1128/JVI.02257-16. Print 2017 May 1. J Virol. 2017. PMID: 28228587 Free PMC article.
Several prophylactic vaccines targeting herpes simplex virus 2 (HSV-2) have failed in the clinic to demonstrate sustained depression of viral shedding or protection from recurrences. ...These immunological responses were coincident with a suppression o …
Several prophylactic vaccines targeting herpes simplex virus 2 (HSV-2) have failed in the clinic to demonstrate sustain …
HIV positive patient with HSV-2 encephalitis: case report.
Pagliano P, Ascione T, Carleo MA, Boccia G, De Caro F, Tortora F. Pagliano P, et al. Infez Med. 2016 Sep 1;24(3):245-9. Infez Med. 2016. PMID: 27668908 Free article.
Herpes Simplex Virus type 2 (HSV-2) is an infrequent cause of encephalitis in HIV patients despite it is frequently involved in sexual transmitted infections. ...Twelve months after HSV-2 encephalitis neurologic evaluation was normal, but sympto …
Herpes Simplex Virus type 2 (HSV-2) is an infrequent cause of encephalitis in HIV patients despite it is frequently inv …
Association between virus exposure and depression in US adults.
Gale SD, Berrett AN, Erickson LD, Brown BL, Hedges DW. Gale SD, et al. Psychiatry Res. 2018 Mar;261:73-79. doi: 10.1016/j.psychres.2017.12.037. Epub 2017 Dec 20. Psychiatry Res. 2018. PMID: 29287239
In this study, we sought to evaluate further associations between viral exposure and depression. From the US Center for Disease Control's National Health and Nutrition Examination Survey, we obtained data about depression status, antidepressant use, exposure …
In this study, we sought to evaluate further associations between viral exposure and depression. From the US Center for Disease Contr …
The association of depression, risky sexual behaviours and herpes simplex virus type 2 in adults in NHANES, 2005-2008.
Pratt LA, Xu F, McQuillan GM, Robitz R. Pratt LA, et al. Sex Transm Infect. 2012 Feb;88(1):40-4. doi: 10.1136/sextrans-2011-050138. Epub 2011 Nov 5. Sex Transm Infect. 2012. PMID: 22057015
The authors also examined the association between depression and infection with herpes simplex virus type 2 (HSV-2), a biological marker of risky sexual behaviours. ...Among 3940 adults aged 20-49 years, 19% had HSV-2 infection. Persons w …
The authors also examined the association between depression and infection with herpes simplex virus type 2 (HSV-2
The effects of daily distress and personality on genital HSV shedding and lesions in a randomized, double-blind, placebo-controlled, crossover trial of acyclovir in HSV-2 seropositive women.
Strachan E, Saracino M, Selke S, Magaret A, Buchwald D, Wald A. Strachan E, et al. Brain Behav Immun. 2011 Oct;25(7):1475-81. doi: 10.1016/j.bbi.2011.06.003. Epub 2011 Jun 13. Brain Behav Immun. 2011. PMID: 21693182 Free PMC article. Clinical Trial.
Herpes simplex virus (HSV) infections are ubiquitous in humans, but the determinants of clinical and virologic severity are not completely understood. ...We report results from a randomized, double-blind, placebo-controlled, crossover trial of acyclovir in 19 women for who …
Herpes simplex virus (HSV) infections are ubiquitous in humans, but the determinants of clinical and virologic severity are not compl …
Impact of stepping stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: cluster randomised controlled trial.
Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Puren A, Duvvury N. Jewkes R, et al. BMJ. 2008 Aug 7;337:a506. doi: 10.1136/bmj.a506. BMJ. 2008. PMID: 18687720 Free PMC article. Clinical Trial.
Interviewers administered questionnaires at baseline and 12 and 24 months and blood was tested for HIV and HSV-2. PRIMARY OUTCOME MEASURE: incidence of HIV. Other outcomes: incidence of HSV-2, unwanted pregnancy, reported sexual practices, depressio
Interviewers administered questionnaires at baseline and 12 and 24 months and blood was tested for HIV and HSV-2. PRIMARY OUTC …
IL-2 gene and antisense TGF-beta1 strategies counteract HSV-2 transformed tumor progression.
Kettering JD, Mohamedali AM, Green LM, Gridley DS. Kettering JD, et al. Technol Cancer Res Treat. 2003 Jun;2(3):211-21. doi: 10.1177/153303460300200305. Technol Cancer Res Treat. 2003. PMID: 12779352 Free article.
TGF-beta can diminish immune capacity, whereas interleukin 2 (IL-2) is stimulatory to the immune system and can counteract the negative effects of TGF-beta1. The H238-BALB/c system provides a syngeneic model to evaluate new strategies with the potential to ameliorat …
TGF-beta can diminish immune capacity, whereas interleukin 2 (IL-2) is stimulatory to the immune system and can counteract the …
Lifetime pathogen burden, inflammatory markers, and depression in community-dwelling older adults.
Lu Y, Liu BP, Tan CT, Pan F, Larbi A, Ng TP. Lu Y, et al. Brain Behav Immun. 2022 May;102:124-134. doi: 10.1016/j.bbi.2022.02.020. Epub 2022 Feb 22. Brain Behav Immun. 2022. PMID: 35202734
We profiled in 884 participants in the Singapore Longitudinal Ageing Studies, mean (SD) age: 67.9 (8.1) years, their seropositivities for 11 pathogens (CMV, HSV 1, HSV 2, HHV-6, EBV, VZV, RSV, Dengue, Chikungunya, H. Pylori and Plasmodium) and pathogen burden …
We profiled in 884 participants in the Singapore Longitudinal Ageing Studies, mean (SD) age: 67.9 (8.1) years, their seropositivities for 11 …
Herpes Simplex Encephalitis: An Uncommon Presentation.
Kaeley N, Bansal S, Bhatia R, Ahmad S. Kaeley N, et al. J Clin Diagn Res. 2016 May;10(5):OD25-6. doi: 10.7860/JCDR/2016/19040.7801. Epub 2016 May 1. J Clin Diagn Res. 2016. PMID: 27437286 Free PMC article.
Herpes Simplex Virus (HSV) encephalitis is an uncommon illness, with about 2 cases per 250,000 per year. Most are caused by HSV-1, with 10% having HSV-2 as the aetiologic factor. We present a case of Herpes simplex type1encephalitis in a 70 year …
Herpes Simplex Virus (HSV) encephalitis is an uncommon illness, with about 2 cases per 250,000 per year. Most are caused by …
Association of Depressed Mood With Herpes Simplex Virus-2 Immunoglobulin-G Levels in Pregnancy.
Hsu PC, Yolken RH, Postolache TT, Beckie TM, Munro CL, Groer MW. Hsu PC, et al. Psychosom Med. 2016 Oct;78(8):966-972. doi: 10.1097/PSY.0000000000000374. Psychosom Med. 2016. PMID: 27490851 Free PMC article.
The data included demographics, scores on the Perceived Stress Scale and Profile of Mood States (POMS), and a panel of serum IgG levels for human herpesviruses. RESULTS: Only the herpes simplex virus type 2 (HSV-2) (genital herpes) IgG level was associ …
The data included demographics, scores on the Perceived Stress Scale and Profile of Mood States (POMS), and a panel of serum IgG levels for …
35 results