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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1896 2
1898 3
1901 1
1902 1
1905 1
1907 2
1909 1
1910 2
1911 3
1912 4
1913 2
1914 1
1915 1
1916 1
1917 4
1918 2
1919 2
1920 5
1921 2
1922 3
1923 5
1924 1
1925 5
1926 8
1927 5
1928 7
1929 2
1930 9
1931 3
1932 5
1933 9
1934 2
1935 4
1936 10
1937 3
1938 2
1939 2
1940 7
1941 4
1942 9
1943 1
1944 3
1945 6
1946 12
1947 11
1948 18
1949 14
1950 19
1951 31
1952 49
1953 54
1954 61
1955 106
1956 114
1957 86
1958 107
1959 117
1960 111
1961 109
1962 134
1963 107
1964 161
1965 195
1966 216
1967 274
1968 302
1969 344
1970 399
1971 556
1972 674
1973 748
1974 1403
1975 3152
1976 3304
1977 3328
1978 3385
1979 3937
1980 4603
1981 5450
1982 6223
1983 7330
1984 8379
1985 8877
1986 9467
1987 9825
1988 10248
1989 11426
1990 12423
1991 13013
1992 14080
1993 14879
1994 15649
1995 16223
1996 16141
1997 16233
1998 16958
1999 17027
2000 18604
2001 19326
2002 19728
2003 21159
2004 22643
2005 24595
2006 25811
2007 27334
2008 28154
2009 29389
2010 32590
2011 34750
2012 37757
2013 39536
2014 39949
2015 40538
2016 40743
2017 41643
2018 41993
2019 43272
2020 46972
2021 48568
2022 43729
2023 40612
2024 48947
2025 48490
2026 357

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1,068,256 results

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Page 1
The Influence of Cell Culture Density on the Cytotoxicity of Adipose-Derived Stem Cells Induced by L-Ascorbic Acid-2-Phosphate.
Wu YK, Tu YK, Yu J, Cheng NC. Wu YK, et al. Sci Rep. 2020 Jan 9;10(1):104. doi: 10.1038/s41598-019-56875-0. Sci Rep. 2020. PMID: 31919399 Free PMC article.
Ascorbic acid-2-phosphate (A2-P) is an oxidation-resistant derivative of ascorbic acid that has been widely employed in culturing adipose-derived stem cells (ASCs) for faster expansion and cell sheet formation. ...In this study, the relationship betwee …
Ascorbic acid-2-phosphate (A2-P) is an oxidation-resistant derivative of ascorbic acid that has been widely employed in culturing adi …
Platelet-Derived S1P and Its Relevance for the Communication with Immune Cells in Multiple Human Diseases.
Tolksdorf C, Moritz E, Wolf R, Meyer U, Marx S, Bien-Möller S, Garscha U, Jedlitschky G, Rauch BH. Tolksdorf C, et al. Int J Mol Sci. 2022 Sep 7;23(18):10278. doi: 10.3390/ijms231810278. Int J Mol Sci. 2022. PMID: 36142188 Free PMC article. Review.
S1P regulates cellular proliferation, migration, and apoptosis as well as the function of immune cells. S1P is generated from sphingosine (Sph), which derives from the ceramide metabolism. ...In addition, platelet-dependently generated and released S1P may also infl …
S1P regulates cellular proliferation, migration, and apoptosis as well as the function of immune cells. S1P is generated from sphingo …
Flexible, microstructured surfaces using chitin-derived biopolymers.
Pradhan S, Moore KM, Ainslie KM, Yadavalli VK. Pradhan S, et al. J Mater Chem B. 2019 Sep 11;7(35):5328-5335. doi: 10.1039/c9tb00965e. J Mater Chem B. 2019. PMID: 31389964
In this work, we propose a facile reaction to modify the chitin chain with photoactive moieties for the realization of photocrosslinkable chitin. This chitin derivative is easily usable with a benign solvent formic acid to be able to form mechanically robust, optically tra …
In this work, we propose a facile reaction to modify the chitin chain with photoactive moieties for the realization of photocrosslinkable ch …
Characterization of goat inner cell mass derived cells in double kinase inhibition condition.
Wei Q, Xi Q, Liu X, Meng K, Zhao X, Ma B. Wei Q, et al. Biochem Biophys Res Commun. 2017 Jan 29;483(1):325-331. doi: 10.1016/j.bbrc.2016.12.144. Epub 2016 Dec 23. Biochem Biophys Res Commun. 2017. PMID: 28025142
In present study, goat inner cell mass (ICM) derived cells in the double inhibition (2i) condition, in which, mitogen-activated protein kinase kinase (MAP2K) and glycogen synthase kinase 3 (GSK3) were inhibited by PD0325901 and BIO respectively, were characte …
In present study, goat inner cell mass (ICM) derived cells in the double inhibition (2i) condition, in which, mitogen-a …
Retinoblastoma Cell Culturing and Evaluation of Their Drug Resistance.
Saakyan SV, Tsygankov АY, Moiseeva NI, Karamysheva АF, Zhil'tsova MG, Tadevosyan SS. Saakyan SV, et al. Bull Exp Biol Med. 2018 May;165(1):148-153. doi: 10.1007/s10517-018-4117-7. Epub 2018 May 24. Bull Exp Biol Med. 2018. PMID: 29796815
Samples of the tumor tissue were taken to derive a cell culture and to study drug resistance and metabolic activity of cells (MTT test). ...MTT test revealed no differences in the sensitivity of cell cultures to irinotecan and ifosfamide. Pronounced di …
Samples of the tumor tissue were taken to derive a cell culture and to study drug resistance and metabolic activity of cell …
Inhibitory effects of acyclic retinoid (polyprenoic acid) and its hydroxy derivative on cell growth and on secretion of alpha-fetoprotein in human hepatoma-derived cell line (PLC/PRF/5).
Fukutomi Y, Omori M, Muto Y, Ninomiya M, Okuno M, Moriwaki H. Fukutomi Y, et al. Jpn J Cancer Res. 1990 Dec;81(12):1281-5. doi: 10.1111/j.1349-7006.1990.tb02691.x. Jpn J Cancer Res. 1990. PMID: 1703522 Free PMC article.
We studied the effects of acyclic retinoid, the 7-hydroxy derivative of acyclic retinoid (7OH-acyclic retinoid) and retinoic acid on a human hepatoma-derived cell line PLC/PRF/5 (Alexander cells). Acyclic retinoid inhibited cell growth with an I …
We studied the effects of acyclic retinoid, the 7-hydroxy derivative of acyclic retinoid (7OH-acyclic retinoid) and retinoic acid on …
Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers.
Theodoropoulos PC, Guo HH, Wang W, Crossley E, Rivera Cancel G, Fang M, Nguyen T, Baniasadi H, Williams NS, Ready JM, De Brabander JK, Nijhawan D. Theodoropoulos PC, et al. ACS Chem Biol. 2024 Jun 21;19(6):1339-1350. doi: 10.1021/acschembio.4c00170. Epub 2024 Jun 3. ACS Chem Biol. 2024. PMID: 38829020 Free PMC article.
Compound 9 is metabolized by NAMPT and NMNAT1 into an adenine dinucleotide (AD) derivative in a cell-free system, cultured cells, and mice, and inhibition of this metabolism blocked compound activity. AD analogues derived from compound 9 inhibit IMPDH …
Compound 9 is metabolized by NAMPT and NMNAT1 into an adenine dinucleotide (AD) derivative in a cell-free system, cultured …
Is hypusine essential for eukaryotic cell proliferation?
Park MH, Wolff EC, Folk JE. Park MH, et al. Trends Biochem Sci. 1993 Dec;18(12):475-9. doi: 10.1016/0968-0004(93)90010-k. Trends Biochem Sci. 1993. PMID: 8108861 Review.
Hypusine [N epsilon-(4-amino-2-hydroxybutyl)-L-lysine] is a most remarkable amino acid, occurring in all eukaryotic cells, yet occupying only a single position in one protein, eukaryotic protein synthesis initiation factor 5A (eIF-5A). The unusual structure of hypusine, it …
Hypusine [N epsilon-(4-amino-2-hydroxybutyl)-L-lysine] is a most remarkable amino acid, occurring in all eukaryotic cells, yet occupy …
A leucine derivate-adjuvanted LNP vaccine enhances antitumor immunity through mTOR activation and metabolic reprograming in dendritic cells.
Zhou Y, Xie Y, Qi J, Hu J, Yang Y, Deng F, Zhu Y, Deng W, Mei L, Goldys EM, Zhang J, Xu C, Chen W. Zhou Y, et al. Biomaterials. 2026 Feb;325:123539. doi: 10.1016/j.biomaterials.2025.123539. Epub 2025 Jul 8. Biomaterials. 2026. PMID: 40664088
Neoantigen-derived peptide vaccines have been emergingly employed to treat tumors, however, their inefficient delivery and antigenicity remain challenging. In this study, for the first time a leucine derivate LLOMe (L-leucyl-l-leucine methyl ester) was repurposed to …
Neoantigen-derived peptide vaccines have been emergingly employed to treat tumors, however, their inefficient delivery and antigenici …
Isorhamnetin Suppresses Human Gastric Cancer Cell Proliferation through Mitochondria-Dependent Apoptosis.
Li Y, Fan B, Pu N, Ran X, Lian T, Cai Y, Xing W, Sun K. Li Y, et al. Molecules. 2022 Aug 15;27(16):5191. doi: 10.3390/molecules27165191. Molecules. 2022. PMID: 36014431 Free PMC article.
Derivates of natural products have been wildly utilized in the treatment of malignant tumors. ...These results are consistent with the transcriptomic analysis of ISO-treated GC cells, which yielded hundreds of differentially expressed genes that were enriched with …
Derivates of natural products have been wildly utilized in the treatment of malignant tumors. ...These results are consistent with th …
1,068,256 results
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