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Year Number of Results
1969 1
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21 results

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Page 1
Effect of lipid emulsion on neuropsychiatric drug-induced toxicity: A narrative review.
Hwang Y, Sohn JT. Hwang Y, et al. Medicine (Baltimore). 2024 Mar 15;103(11):e37612. doi: 10.1097/MD.0000000000037612. Medicine (Baltimore). 2024. PMID: 38489675 Free PMC article. Review.
The goal of this study was to examine the effect of lipid emulsions on neuropsychiatric drug-induced toxicity using relevant case reports of human patients, with a particular focus on the Glasgow Coma Scale (GCS) score and corrected QT interval, to analyze drugs that frequ …
The goal of this study was to examine the effect of lipid emulsions on neuropsychiatric drug-induced toxicity using relevant case reports of …
Psychotropic drugs and the ECG: focus on the QTc interval.
Goodnick PJ, Jerry J, Parra F. Goodnick PJ, et al. Expert Opin Pharmacother. 2002 May;3(5):479-98. doi: 10.1517/14656566.3.5.479. Expert Opin Pharmacother. 2002. PMID: 11996627 Review.
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the development of torsades de pointes and sudden death, particularly in patients predisposed to these complications due to cardiovascular impairme …
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the developmen …
Tricyclic medication in children and the QT interval: case report and discussion.
Alderton HR. Alderton HR. Can J Psychiatry. 1995 Aug;40(6):325-9. Can J Psychiatry. 1995. PMID: 7585402 Review.
OBJECTIVE: To identify the necessity for close monitoring of the QT interval in children and adolescents treated with tricyclics. METHOD: Guidelines for permissible ECG changes are reviewed and a case report of a 12-year-old girl with idiopathic long QT syndrome, no …
OBJECTIVE: To identify the necessity for close monitoring of the QT interval in children and adolescents treated with tricyclics. MET …
2-Hydroxydesipramine and desipramine plasma levels and electrocardiographic effects in depressed younger adults.
Stern SL, Ribner HS, Cooper TB, Nelson LD, Johnson MH, Suckow RF. Stern SL, et al. J Clin Psychopharmacol. 1991 Apr;11(2):93-8. J Clin Psychopharmacol. 1991. PMID: 2056147 Clinical Trial.
Desipramine was given to 34 outpatients aged 20 to 51 years who had primary major depressive disorder but who were otherwise in good health. ...Plasma samples drawn 14 hours after the final study dose were assayed by high performance liquid chromatography; mean (SD) levels …
Desipramine was given to 34 outpatients aged 20 to 51 years who had primary major depressive disorder but who were otherwise in good …
Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents.
Leonard HL, Meyer MC, Swedo SE, Richter D, Hamburger SD, Allen AJ, Rapoport JL, Tucker E. Leonard HL, et al. J Am Acad Child Adolesc Psychiatry. 1995 Nov;34(11):1460-8. doi: 10.1097/00004583-199511000-00012. J Am Acad Child Adolesc Psychiatry. 1995. PMID: 8543513 Clinical Trial.
OBJECTIVE: With the increased use of tricyclic antidepressants in children, and several reports of several sudden deaths associated with desipramine (DMI) treatment, systematic study of their cardiac effects is indicated. In the present study, DMI's and clomipramine's (CMI …
OBJECTIVE: With the increased use of tricyclic antidepressants in children, and several reports of several sudden deaths associated with …
Desipramine and the EKG.
Smith RH. Smith RH. J Am Acad Child Adolesc Psychiatry. 1992 May;31(3):564-5. J Am Acad Child Adolesc Psychiatry. 1992. PMID: 1592794 No abstract available.
ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine.
Johnson A, Giuffre RM, O'Malley K. Johnson A, et al. Can J Psychiatry. 1996 Mar;41(2):102-6. doi: 10.1177/070674379604100207. Can J Psychiatry. 1996. PMID: 8705955
The QT interval was corrected for heart rate (QTc). No significant arrhythmias or tachycardias were observed. ...CONCLUSIONS: No consistent pattern of ECG interval changes including the QTc interval was observed in children on desipramine and imipramine....
The QT interval was corrected for heart rate (QTc). No significant arrhythmias or tachycardias were observed. ...CONCLUSIONS: No cons …
Another sudden death in a child treated with desipramine.
Riddle MA, Geller B, Ryan N. Riddle MA, et al. J Am Acad Child Adolesc Psychiatry. 1993 Jul;32(4):792-7. doi: 10.1097/00004583-199307000-00013. J Am Acad Child Adolesc Psychiatry. 1993. PMID: 8340300 Free article. Review.
Because desipramine is a useful medication for many children, these deaths pose clinical dilemmas for physicians and families. The cardiac long QT syndrome has been proposed as a mechanism for these sudden deaths. Considerable uncertainty remains about the basis of …
Because desipramine is a useful medication for many children, these deaths pose clinical dilemmas for physicians and families. The ca …
hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine.
Staudacher I, Wang L, Wan X, Obers S, Wenzel W, Tristram F, Koschny R, Staudacher K, Kisselbach J, Koelsch P, Schweizer PA, Katus HA, Ficker E, Thomas D. Staudacher I, et al. Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):119-39. doi: 10.1007/s00210-010-0583-9. Epub 2010 Dec 1. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21120454
Adverse effects precipitated by the tricyclic drug desipramine include prolonged QT intervals, torsade de pointes tachycardia, heart failure, and sudden cardiac death. ...Action potential duration was prolonged upon acute and chronic desipramine exposu …
Adverse effects precipitated by the tricyclic drug desipramine include prolonged QT intervals, torsade de pointes tachy …
Electrocardiographic safety profile and monitoring guidelines in pediatric psychopharmacology.
Blair J, Taggart B, Martin A. Blair J, et al. J Neural Transm (Vienna). 2004 Jul;111(7):791-815. doi: 10.1007/s00702-004-0153-8. J Neural Transm (Vienna). 2004. PMID: 15205999 Review.
QTc prolongation can in turn predispose to torsades de pointes, a sometimes deadly arrhythmia. These considerations are clinically relevant given documented, if still controversial, reports of sudden deaths associated with the use of the tricyclic antidepressant (TCA) d …
QTc prolongation can in turn predispose to torsades de pointes, a sometimes deadly arrhythmia. These considerations are clinically re …
21 results