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Page 1
Approach to the Patient: Diagnosis of Cushing Syndrome.
Savas M, Mehta S, Agrawal N, van Rossum EFC, Feelders RA. Savas M, et al. J Clin Endocrinol Metab. 2022 Nov 23;107(11):3162-3174. doi: 10.1210/clinem/dgac492. J Clin Endocrinol Metab. 2022. PMID: 36036941 Free PMC article.
An early diagnosis of Cushing syndrome is warranted; however, in clinical practice, it is very challenging partly because of resemblance with other common conditions (ie, pseudo-Cushing syndrome). Initial workup should start with excluding local and systemic cortico …
An early diagnosis of Cushing syndrome is warranted; however, in clinical practice, it is very challenging partly because of resemblance wit …
Factors Affecting Dexamethasone Suppression Test Results.
Berlińska A, Świątkowska-Stodulska R, Sworczak K. Berlińska A, et al. Exp Clin Endocrinol Diabetes. 2020 Oct;128(10):667-671. doi: 10.1055/a-1017-3217. Epub 2019 Oct 25. Exp Clin Endocrinol Diabetes. 2020. PMID: 31652475
Dexamethasone suppression tests are basic tools in diagnostics of hypercortisolemia. Low-dose tests play major role in screening and initial assessment. ...Physicians should be familiar with drugs modifying dexamethasone metabolism, and therefore the results …
Dexamethasone suppression tests are basic tools in diagnostics of hypercortisolemia. Low-dose tests play major role in screeni …
Cushing's disease, pseudo-Cushing states and the dexamethasone test: a historical and critical review.
Lindholm J. Lindholm J. Pituitary. 2014 Aug;17(4):374-80. doi: 10.1007/s11102-013-0509-x. Pituitary. 2014. PMID: 23979450 Review.
The dexamethasone (DXM) test has been widely used for diagnosing Cushing's disease (CD). The purpose of this paper is to review its diagnostic merit based on calculation of data extracted from earlier publications. ...Finally, the generally accepted view that DXM ca …
The dexamethasone (DXM) test has been widely used for diagnosing Cushing's disease (CD). The purpose of this paper is to revie …
Performance of the 4-mg intravenous dexamethasone suppression test in differentiating Cushing disease from pseudo-Cushing syndrome.
Nouvel M, Rabilloud M, Raverot V, Subtil F, Vouillarmet J, Thivolet C, Jouanneau E, Borson-Chazot F, Pugeat M, Raverot G. Nouvel M, et al. Ann Endocrinol (Paris). 2016 Feb;77(1):30-6. doi: 10.1016/j.ando.2015.11.001. Epub 2015 Dec 3. Ann Endocrinol (Paris). 2016. PMID: 26656734
CONTEXT: Discriminating Cushing disease (CD) from pseudo-Cushing syndrome (PCS) is a challenging task that may be overcome with the 4-mg intravenous (IV) dexamethasone suppression test (DST). OBJECTIVE: Assess the performance of the 4-mg IV DST …
CONTEXT: Discriminating Cushing disease (CD) from pseudo-Cushing syndrome (PCS) is a challenging task that may be overcome wit …
Reevaluation of the combined dexamethasone suppression-corticotropin-releasing hormone test for differentiation of mild cushing's disease from pseudo-Cushing's syndrome.
Gatta B, Chabre O, Cortet C, Martinie M, Corcuff JB, Roger P, Tabarin A. Gatta B, et al. J Clin Endocrinol Metab. 2007 Nov;92(11):4290-3. doi: 10.1210/jc.2006-2829. Epub 2007 Jul 17. J Clin Endocrinol Metab. 2007. PMID: 17635947
CONTEXT: The diagnostic accuracy of the combined dexamethasone suppression test (DST)-CRH test for the differential diagnosis between Cushing's disease (CD) and pseudo-Cushing syndrome (PCS) has recently been debated. ...RESULTS: A 55 nmo …
CONTEXT: The diagnostic accuracy of the combined dexamethasone suppression test (DST)-CRH test for the different …
Corticotropin-releasing hormone stimulation following low-dose dexamethasone administration. A new test to distinguish Cushing's syndrome from pseudo-Cushing's states.
Yanovski JA, Cutler GB Jr, Chrousos GP, Nieman LK. Yanovski JA, et al. JAMA. 1993 May 5;269(17):2232-8. JAMA. 1993. PMID: 8386285
INTERVENTION: The low-dose dexamethasone suppression test, the CRH stimulation test, and the CRH stimulation test started 2 hours after completion of low-dose dexamethasone suppression (the dexamethasone-CRH test) wer …
INTERVENTION: The low-dose dexamethasone suppression test, the CRH stimulation test, and the CRH stimulation …
The dexamethasone-suppressed corticotropin-releasing hormone stimulation test and the desmopressin test to distinguish Cushing's syndrome from pseudo-Cushing's states.
Pecori Giraldi F, Pivonello R, Ambrogio AG, De Martino MC, De Martin M, Scacchi M, Colao A, Toja PM, Lombardi G, Cavagnini F. Pecori Giraldi F, et al. Clin Endocrinol (Oxf). 2007 Feb;66(2):251-7. doi: 10.1111/j.1365-2265.2006.02717.x. Clin Endocrinol (Oxf). 2007. PMID: 17223996 Clinical Trial.
DESIGN: The study population comprised 32 patients with CS and 23 with pseudo-Cushing's evaluated retrospectively. ...The greatest diagnostic effectiveness results from the low-dose dexamethasone test combined with the desmopressin test. …
DESIGN: The study population comprised 32 patients with CS and 23 with pseudo-Cushing's evaluated retrospectively. ...T …
The dexamethasone-suppressed corticotropin-releasing hormone stimulation test differentiates mild Cushing's disease from normal physiology.
Yanovski JA, Cutler GB Jr, Chrousos GP, Nieman LK. Yanovski JA, et al. J Clin Endocrinol Metab. 1998 Feb;83(2):348-52. doi: 10.1210/jcem.83.2.4568. J Clin Endocrinol Metab. 1998. PMID: 9467539 Free PMC article.
The dexamethasone-suppressed CRH test (Dex-CRH test) differentiates patients with Cushing's syndrome (CS) from those with pseudo-Cushing states, who have decreased ACTH responses to CRH because of negative feedback exerted by chronic hype …
The dexamethasone-suppressed CRH test (Dex-CRH test) differentiates patients with Cushing's syndrome (CS) from t …
Cushing’s disease and melancholia.
Condren RM, Thakore JH. Condren RM, et al. Stress. 2001 Jun;4(2):91-119. doi: 10.3109/10253890109115725. Stress. 2001. PMID: 22432130 Free article. Review.
Striking similarities exist in the endocrinology of Cushing's disease and melancholic depression.Laboratory abnormalities, which have been found in both, include raised urinary,plasma and salivary cortisol, non-suppression of cortisol in the dexamethasone suppres …
Striking similarities exist in the endocrinology of Cushing's disease and melancholic depression.Laboratory abnormalities, which have been f …
The difficulties of pseudo-Cushing's syndrome (or "non-neoplastic hypercortisolism").
Chabre O. Chabre O. Ann Endocrinol (Paris). 2018 Jun;79(3):138-145. doi: 10.1016/j.ando.2018.04.017. Epub 2018 Apr 30. Ann Endocrinol (Paris). 2018. PMID: 29716734 Review.
Pseudo-Cushing's syndrome covers different pathological conditions responsible for mild-to-moderate ACTH-dependent hypercortisolism, related not to an ACTH-secreting tumor but rather to CRH and/or AVP hypothalamic secretion through activation of various neural pathw …
Pseudo-Cushing's syndrome covers different pathological conditions responsible for mild-to-moderate ACTH-dependent hypercortis …
44 results