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Page 1
Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity.
Pallavicini G, Moccia A, Iegiani G, Parolisi R, Peirent ER, Berto GE, Lorenzati M, Tshuva RY, Ferraro A, Balzac F, Turco E, Salvi SU, Myklebust HF, Wang S, Eisenberg J, Chitale M, Girgla NS, Boda E, Reiner O, Buffo A, Di Cunto F, Bielas SL. Pallavicini G, et al. Among authors: di cunto f. J Clin Invest. 2024 Nov 1;134(21):e175435. doi: 10.1172/JCI175435. J Clin Invest. 2024. PMID: 39316437 Free PMC article.
Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome.
Chiotto AMA, Migliorero M, Pallavicini G, Bianchi FT, Gai M, Di Cunto F, Berto GE. Chiotto AMA, et al. Among authors: di cunto f. Front Neurosci. 2019 Oct 10;13:1081. doi: 10.3389/fnins.2019.01081. eCollection 2019. Front Neurosci. 2019. PMID: 31649502 Free PMC article.
Correction to: The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.
Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P. Grasso S, et al. Among authors: di cunto f. Cell Death Differ. 2020 Apr;27(4):1448. doi: 10.1038/s41418-019-0405-7. Cell Death Differ. 2020. PMID: 31488891 Free PMC article.
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.
Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P. Grasso S, et al. Among authors: di cunto f. Cell Death Differ. 2020 Feb;27(2):790-807. doi: 10.1038/s41418-019-0386-6. Epub 2019 Jul 8. Cell Death Differ. 2020. PMID: 31285546 Free PMC article.
p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice.
Burla R, La Torre M, Zanetti G, Bastianelli A, Merigliano C, Del Giudice S, Vercelli A, Di Cunto F, Boido M, Vernì F, Saggio I. Burla R, et al. Among authors: di cunto f. Front Genet. 2018 Nov 27;9:581. doi: 10.3389/fgene.2018.00581. eCollection 2018. Front Genet. 2018. PMID: 30546381 Free PMC article.
Correction to: ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly.
El Ghouzzi V, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AMA, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F. El Ghouzzi V, et al. Among authors: di cunto f. Cell Death Dis. 2018 Nov 20;9(12):1155. doi: 10.1038/s41419-018-1159-8. Cell Death Dis. 2018. PMID: 30459303 Free PMC article.
A novel p.Ser108LeufsTer15 SOD1 mutation leading to the formation of a premature stop codon in an apparently sporadic ALS patient: insights into the underlying pathomechanisms.
Canosa A, De Marco G, Lomartire A, Rinaudo MT, Di Cunto F, Turco E, Barberis M, Brunetti M, Casale F, Moglia C, Calvo A, Marklund SL, Andersen PM, Mora G, Chiò A. Canosa A, et al. Among authors: di cunto f. Neurobiol Aging. 2018 Dec;72:189.e11-189.e17. doi: 10.1016/j.neurobiolaging.2018.08.014. Epub 2018 Aug 24. Neurobiol Aging. 2018. PMID: 30236613 Free article.
IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.
Bandini C, Pupuleku A, Spaccarotella E, Pellegrino E, Wang R, Vitale N, Duval C, Cantarella D, Rinaldi A, Provero P, Di Cunto F, Medico E, Bertoni F, Inghirami G, Piva R. Bandini C, et al. Among authors: di cunto f. Cancers (Basel). 2018 Jan 18;10(1):21. doi: 10.3390/cancers10010021. Cancers (Basel). 2018. PMID: 29346274 Free PMC article.
Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly.
Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M, Berto GE, Chiotto AM, Sgrò F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S, Mauro A, Geley S, Gatti M, Di Cunto F. Bianchi FT, et al. Among authors: di cunto f. Cell Rep. 2017 Feb 14;18(7):1674-1686. doi: 10.1016/j.celrep.2017.01.054. Cell Rep. 2017. PMID: 28199840 Free PMC article.
ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53.
Ghouzzi VE, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AM, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F. Ghouzzi VE, et al. Among authors: di cunto f. Cell Death Dis. 2017 Jan 19;8(1):e2567. doi: 10.1038/cddis.2016.446. Cell Death Dis. 2017. PMID: 28102842 Free PMC article. No abstract available.
ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly.
Ghouzzi VE, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AM, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F. Ghouzzi VE, et al. Among authors: di cunto f. Cell Death Dis. 2016 Oct 27;7(10):e2440. doi: 10.1038/cddis.2016.266. Cell Death Dis. 2016. PMID: 27787521 Free PMC article.
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
Gai M, Bianchi FT, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto AM, Annaratone L, Sapino A, Bergo A, Landsberger N, Bond J, Huttner WB, Di Cunto F. Gai M, et al. Among authors: di cunto f. EMBO Rep. 2016 Oct;17(10):1396-1409. doi: 10.15252/embr.201541823. Epub 2016 Aug 25. EMBO Rep. 2016. PMID: 27562601 Free PMC article.
Mutations in Citron Kinase Cause Recessive Microlissencephaly with Multinucleated Neurons.
Harding BN, Moccia A, Drunat S, Soukarieh O, Tubeuf H, Chitty LS, Verloes A, Gressens P, El Ghouzzi V, Joriot S, Di Cunto F, Martins A, Passemard S, Bielas SL. Harding BN, et al. Among authors: di cunto f. Am J Hum Genet. 2016 Aug 4;99(2):511-20. doi: 10.1016/j.ajhg.2016.07.003. Epub 2016 Jul 21. Am J Hum Genet. 2016. PMID: 27453579 Free PMC article.
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P. Repetto D, et al. Among authors: di cunto f. J Neurosci. 2014 Jan 22;34(4):1542-53. doi: 10.1523/JNEUROSCI.2341-13.2014. J Neurosci. 2014. PMID: 24453341 Free PMC article.
STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma.
Spaccarotella E, Pellegrino E, Ferracin M, Ferreri C, Cuccuru G, Liu C, Iqbal J, Cantarella D, Taulli R, Provero P, Di Cunto F, Medico E, Negrini M, Chan WC, Inghirami G, Piva R. Spaccarotella E, et al. Among authors: di cunto f. Haematologica. 2014 Jan;99(1):116-24. doi: 10.3324/haematol.2013.088286. Epub 2013 Aug 23. Haematologica. 2014. PMID: 23975180 Free PMC article.
A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia.
Di Gregorio E, Bianchi FT, Schiavi A, Chiotto AM, Rolando M, Verdun di Cantogno L, Grosso E, Cavalieri S, Calcia A, Lacerenza D, Zuffardi O, Retta SF, Stevanin G, Marelli C, Durr A, Forlani S, Chelly J, Montarolo F, Tempia F, Beggs HE, Reed R, Squadrone S, Abete MC, Brussino A, Ventura N, Di Cunto F, Brusco A. Di Gregorio E, et al. Among authors: di cunto f. J Med Genet. 2013 Aug;50(8):543-51. doi: 10.1136/jmedgenet-2013-101542. Epub 2013 Jun 7. J Med Genet. 2013. PMID: 23749989 Free PMC article.
90 results