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Factors Mediating Type 2 Diabetes Remission and Relapse after Gastric Bypass Surgery.
Pessoa BM, Browning MG, Mazzini GS, Wolfe L, Kaplan A, Khoraki J, Campos GM. Pessoa BM, et al. J Am Coll Surg. 2020 Jan;230(1):7-16. doi: 10.1016/j.jamcollsurg.2019.09.012. Epub 2019 Oct 28. J Am Coll Surg. 2020. PMID: 31672669
BACKGROUND: Defining factors associated with remission and relapse of type 2 diabetes (T2D) after Roux-en-Y gastric bypass (RYGB) can allow targeting modifiable factors. ...Ninety-three percent of remissions occurred within 3 years of RYGB, 25% rela …
BACKGROUND: Defining factors associated with remission and relapse of type 2 diabetes (T2D) after Roux-en-Y gastric byp …
Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial.
Mingrone G, Panunzi S, De Gaetano A, Guidone C, Iaconelli A, Capristo E, Chamseddine G, Bornstein SR, Rubino F. Mingrone G, et al. Lancet. 2021 Jan 23;397(10271):293-304. doi: 10.1016/S0140-6736(20)32649-0. Lancet. 2021. PMID: 33485454 Clinical Trial.
In the 10-year analysis, durability of diabetes remission was analysed by intention to treat (ITT). This study is registered with ClinicalTrials.gov, NCT00888836. ...Of all patients who were surgically treated, 15 (37.5%) maintained diabetes remissi …
In the 10-year analysis, durability of diabetes remission was analysed by intention to treat (ITT). This study is regis …
Determinants of Diabetes Remission and Relapse Following Sleeve Gastrectomy and Gastric Bypass: A 2- and 5-Year Follow-Up Study.
Leyaro B, Howie L, Ali A, Carragher R. Leyaro B, et al. Obes Facts. 2026 Apr 15:1-19. doi: 10.1159/000552002. Online ahead of print. Obes Facts. 2026. PMID: 41984748 Free article.
INTRODUCTION: Bariatric surgery is an established treatment for obesity and has been shown to improve glycemic control and frequently induces remission of type 2 diabetes mellitus (T2DM). However, the long-term sustainability of remission remains uncer …
INTRODUCTION: Bariatric surgery is an established treatment for obesity and has been shown to improve glycemic control and frequently induce …
Diabetes: Bariatric surgery for T2DM--cure, or remission and relapse?
Goldfine AB, Patti ME. Goldfine AB, et al. Nat Rev Endocrinol. 2014 Jan;10(1):8-9. doi: 10.1038/nrendo.2013.222. Epub 2013 Oct 29. Nat Rev Endocrinol. 2014. PMID: 24165996 Free PMC article.
Postoperative metabolic improvements in glucose levels, blood pressure and lipids have led to recognition that surgery may prove to be a highly effective therapy for type 2 diabetes (T2D). A recent report evaluates durability of diabetes remission and …
Postoperative metabolic improvements in glucose levels, blood pressure and lipids have led to recognition that surgery may prove to be a hig …
Diabetes Remission After Bariatric Surgery: A 10-Year Follow-Up Study.
Meira I, Menino J, Ferreira P, Leite AR, Gonçalves J, Ferreira HU, Ribeiro S, Moreno T, Silva DF, Pedro J, Varela A, Souto S, Freitas P, da Costa EL, Queirós J, Group C. Meira I, et al. Obes Surg. 2025 Jan;35(1):161-169. doi: 10.1007/s11695-024-07592-9. Epub 2024 Dec 23. Obes Surg. 2025. PMID: 39715944 Free PMC article.
AIM: Determine the incidence of durable remission and relapse of T2DM rates 10 years after MBS, characterize the glycemic profile after surgery, and identify factors predicting persistent remission of T2DM. ...Ten years after surgery, the rate of compl …
AIM: Determine the incidence of durable remission and relapse of T2DM rates 10 years after MBS, characterize the glycem …
Preoperative predictors of type 2 diabetes remission after bilio-pancreatic diversion with duodenal switch.
Lajeunesse-Trempe F, Piché ME, Marceau S, Lebel S, Lafortune A, Dimitriadis GK, Tchernof A, Biertho L. Lajeunesse-Trempe F, et al. Surg Obes Relat Dis. 2024 Jun;20(6):507-514. doi: 10.1016/j.soard.2023.11.006. Epub 2023 Nov 25. Surg Obes Relat Dis. 2024. PMID: 38172004
BACKGROUND: Many patients achieve short-term type 2 diabetes (T2D) remission after bariatric surgery, but relapses are common. Diabetes outcomes after bariatric surgery vary across procedures and populations. ...Duration of T2D alone offers an excellen …
BACKGROUND: Many patients achieve short-term type 2 diabetes (T2D) remission after bariatric surgery, but relapses are …
A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass.
Arterburn DE, Bogart A, Sherwood NE, Sidney S, Coleman KJ, Haneuse S, O'Connor PJ, Theis MK, Campos GM, McCulloch D, Selby J. Arterburn DE, et al. Obes Surg. 2013 Jan;23(1):93-102. doi: 10.1007/s11695-012-0802-1. Obes Surg. 2013. PMID: 23161525 Free PMC article.
BACKGROUND: Gastric bypass has profound effects on glycemic control in adults with type 2 diabetes mellitus. The goal of this study was to examine the long-term rates and clinical predictors of diabetes remission and relapse among patients under …
BACKGROUND: Gastric bypass has profound effects on glycemic control in adults with type 2 diabetes mellitus. The goal of this …
Clinical and Demographic Characteristics Associated With Diabetes Remission in Six Integrated Health Care Systems: A Retrospective Cohort Study.
Thapa B, Schmittdiel JA, Arterburn D, Neugebauer R, Dyer W, O'Connor PJ, An J, Cassidy-Bushrow AE, Gilliam LK, Hooker SA, Nolan MB, Oshiro CES, Thomas T, Simonson G, Dombrowski SK, Rodriguez LA. Thapa B, et al. Diabetes Care. 2025 Oct 1;48(10):1737-1743. doi: 10.2337/dc25-0530. Diabetes Care. 2025. PMID: 40734551 Free PMC article.
Multivariate logistic regression was used to identify characteristics associated with type 2 diabetes remission. RESULTS: Over a 3-year follow-up, 2.9% (16,016 adults) achieved type 2 diabetes remission, although 36.9% of those who experienced remis …
Multivariate logistic regression was used to identify characteristics associated with type 2 diabetes remission. RESULTS: Over …
Relapse of Diabetes After Roux-en-Y Gastric Bypass for Patients With Obesity: 12 Years Follow-up Study.
Elshaer AM, Almerie MQ, Pellen M, Jain P. Elshaer AM, et al. Obes Surg. 2020 Dec;30(12):4834-4839. doi: 10.1007/s11695-020-04782-z. Epub 2020 Jun 23. Obes Surg. 2020. PMID: 32578178
BACKGROUND: Roux-en-Y gastric bypass (RYGB) is a recommended treatment for type 2 diabetes mellitus (T2DM) in patients with obesity, with superiority over medical therapy. While diabetes remission is achieved initially in 60-90% of patients following s …
BACKGROUND: Roux-en-Y gastric bypass (RYGB) is a recommended treatment for type 2 diabetes mellitus (T2DM) in patients with ob …
The Critical Role of Adipocytes in Leukemia.
Higos R, Saitoski K, Hautefeuille M, Marcelin G, Clément K, Varin-Blank N, Breton C, Lecoutre S, Lambert M. Higos R, et al. Biology (Basel). 2025 May 28;14(6):624. doi: 10.3390/biology14060624. Biology (Basel). 2025. PMID: 40563875 Free PMC article. Review.
This reciprocal and dynamic interaction between leukemic cells and adipocytes contributes significantly to minimal residual disease and relapse, posing a major challenge for durable remission. Recent advances in tissue engineering-such as organ-on-chip and 3D …
This reciprocal and dynamic interaction between leukemic cells and adipocytes contributes significantly to minimal residual disease and r …
36 results