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Intensification of diabetes medication and risk for 30-day readmission.
Wei NJ, Wexler DJ, Nathan DM, Grant RW. Wei NJ, et al. Diabet Med. 2013 Feb;30(2):e56-62. doi: 10.1111/dme.12061. Diabet Med. 2013. PMID: 23126686 Free PMC article.
The association of glucose therapy intensification with subsequent 30-day risk for unplanned readmission/emergency department admission was examined, with focus on medicine service patients with poorly controlled glycaemia (baseline HbA(1c) 64 mmol/mol). ...Overall, glucos …
The association of glucose therapy intensification with subsequent 30-day risk for unplanned readmission/emergency department admission was …
Impaired islet turnover in human donor pancreata with aging.
Reers C, Erbel S, Esposito I, Schmied B, Büchler MW, Nawroth PP, Ritzel RA. Reers C, et al. Eur J Endocrinol. 2009 Feb;160(2):185-91. doi: 10.1530/EJE-08-0596. Epub 2008 Nov 12. Eur J Endocrinol. 2009. PMID: 19004984
RESULTS: Relative beta-cell volume in human pancreata (mean 2.3+/-0.2%) remains constant with aging (r=0.26, P=ns). Beta-cell replication (r=0.71, P=0.0004) decreases age-dependently, while beta-cell apoptosis does not change significantly (r=0.42, P=0.08). ...The rate of …
RESULTS: Relative beta-cell volume in human pancreata (mean 2.3+/-0.2%) remains constant with aging (r=0.26, P=ns). Beta-cell replica …
Sudomotor dysfunction is associated with foot ulceration in diabetes.
Tentolouris N, Marinou K, Kokotis P, Karanti A, Diakoumopoulou E, Katsilambros N. Tentolouris N, et al. Diabet Med. 2009 Mar;26(3):302-5. doi: 10.1111/j.1464-5491.2009.02677.x. Diabet Med. 2009. PMID: 19317826
CONCLUSIONS: Sudomotor dysfunction is associated with increased risk of FU and should be included in the screening tests for identification of diabetic patients at risk of ulceration....
CONCLUSIONS: Sudomotor dysfunction is associated with increased risk of FU and should be included in the screening tests for identification …
Investigation of the effect of oral metformin on dipeptidylpeptidase-4 (DPP-4) activity in Type 2 diabetes.
Cuthbertson J, Patterson S, O'Harte FP, Bell PM. Cuthbertson J, et al. Diabet Med. 2009 Jun;26(6):649-54. doi: 10.1111/j.1464-5491.2009.02748.x. Diabet Med. 2009. PMID: 19538242

Metformin serum levels were significantly lower (P < 0.001) after SMM than fasting (AUC(0-4 h) 350 +/- 66 vs. 457 +/- 55 mg/ml/min). CONCLUSION: Metformin inhibits DPP-4 activity in Type 2 diabetic patients in the fasting state but not when taken with a standard mixed m

Metformin serum levels were significantly lower (P < 0.001) after SMM than fasting (AUC(0-4 h) 350 +/- 66 vs. 457 +/- 55 mg/ml/min). CONC

The effect of metformin on the incidence of type 2 diabetes mellitus and cardiovascular disease risk factors in overweight and obese subjects--the Carmos study.
Andreadis EA, Katsanou PM, Georgiopoulos DX, Tsourous GI, Yfanti GK, Gouveri ET, Diamantopoulos EJ. Andreadis EA, et al. Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):175-80. doi: 10.1055/s-0028-1087177. Epub 2008 Dec 3. Exp Clin Endocrinol Diabetes. 2009. PMID: 19053032
Metformin also achieved a greater reduction in total cholesterol and LDL-C levels (metformin vs. non-metformin treated subjects: -31.9 vs. -17.3 mg/dl, p=0.001, and -26.2 vs. -15.9 mg/dl, p=0.006, respectively). CONCLUSIONS: Metformin reduces the occurrence of T (2)DM in o …
Metformin also achieved a greater reduction in total cholesterol and LDL-C levels (metformin vs. non-metformin treated subjects: -31.9 vs. - …