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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1994 1
1997 1
1998 3
2000 3
2001 1
2002 1
2004 1
2006 3
2007 2
2008 2
2009 2
2010 1
2011 3
2012 4
2013 2
2014 1
2015 2
2016 2
2017 6
2018 3
2019 3
2020 2
2021 3
2022 3
2023 4
2024 0

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56 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Diacerein for osteoarthritis.
Fidelix TS, Macedo CR, Maxwell LJ, Fernandes Moça Trevisani V. Fidelix TS, et al. Cochrane Database Syst Rev. 2014 Feb 10;2014(2):CD005117. doi: 10.1002/14651858.CD005117.pub3. Cochrane Database Syst Rev. 2014. PMID: 24515444 Free PMC article. Review.
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ...With respect to adverse effects of diacerein, diarrhoea was most frequent. Given the recent guidance issued by the EMA recommending s …
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ... …
Is diacerein an alternative for the treatment of osteoarthritis?
Alegría A, Irarrázaval S. Alegría A, et al. Medwave. 2017 Oct 12;17(8):e7041. doi: 10.5867/medwave.2017.08.7041. Medwave. 2017. PMID: 29028791 Review. English, Spanish.
INTRODUCTION: Among the possibilities for the management of osteoarthritis, different pharmacological alternatives have been proposed, being diacerein one of them due to its anti-inflammatory effect. However, diacerein clinical utility is not clear. ...We extracted …
INTRODUCTION: Among the possibilities for the management of osteoarthritis, different pharmacological alternatives have been proposed, being …
Diacerein versus non-steroidal anti-inflammatory drugs in the treatment of knee osteoarthritis: a meta-analysis.
Zeng F, Wang K, Duan H, Xu XT, Kuang GY, Lu M. Zeng F, et al. J Orthop Surg Res. 2023 Apr 18;18(1):308. doi: 10.1186/s13018-023-03786-6. J Orthop Surg Res. 2023. PMID: 37072810 Free PMC article.
Emerging evidence suggests that the multifaceted symptomatology of KOA may be alleviated by diacerein. With this in mind, we conducted a systematic review and meta-analysis to evaluate the efficacy and safety of diacerein in patients with KOA. ...Moreover, there was …
Emerging evidence suggests that the multifaceted symptomatology of KOA may be alleviated by diacerein. With this in mind, we conducte …
Diacerein for osteoarthritis.
Fidelix TS, Soares BG, Trevisani VF. Fidelix TS, et al. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD005117. doi: 10.1002/14651858.CD005117.pub2. Cochrane Database Syst Rev. 2006. PMID: 16437519 Updated. Review.
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure modifying drug for OA. ...AUTHORS' CONCLUSIONS: There is 'gold' level evidence that diacerein has a small, consistent benefit in improvement in pain. Further r …
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure modifying drug for OA. ... …
Diacerein 1% Ointment for the Treatment of Epidermolysis Bullosa Simplex: A Randomized, Controlled Trial.
Teng J, Paller AS, Bruckner AL, Murrell DF, Mellerio JE, Bodemer C, Martinez AE, Lugo-Somolinos A, Sprecher E, Laimer M, Wally V, Chan YM, Lin SY, Spellman M, Bauer JW. Teng J, et al. J Drugs Dermatol. 2023 Jun 1;22(6):599-604. doi: 10.36849/JDD.7108. J Drugs Dermatol. 2023. PMID: 37276163 Clinical Trial.
BACKGROUND: In epidermolysis bullosa simplex (EBS), epithelial structural fragility results in blisters and erosions. Diacerein 1% ointment has been shown to reduce this blistering. OBJECTIVE: To evaluate the efficacy and safety of diacerein 1% ointment in the treat …
BACKGROUND: In epidermolysis bullosa simplex (EBS), epithelial structural fragility results in blisters and erosions. Diacerein 1% oi …
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Liu X, et al. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. Br J Sports Med. 2018. PMID: 29018060 Review.
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondroitin) revealed statistically significant improvements on pain, but were of unclear clinical importance. ...There were no differences between …
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondro …
Diacerein for the treatment of rheumatoid arthritis in patients with inadequate response to methotrexate: a pilot randomized, double-blind, placebo-controlled add-on trial.
Louthrenoo W, Nilganuwong S, Nanagara R, Siripaitoon B, Collaud Basset S. Louthrenoo W, et al. Clin Rheumatol. 2019 Sep;38(9):2461-2471. doi: 10.1007/s10067-019-04587-1. Epub 2019 May 19. Clin Rheumatol. 2019. PMID: 31104217 Clinical Trial.
The ACR20 response at week 24 was similar in the diacerein and placebo groups (65% vs 45%, P = .20). However, treatment response according to the EULAR criteria was better in patients taking diacerein (75% vs 25% of moderate response, P = .002). ...Incidence of adve …
The ACR20 response at week 24 was similar in the diacerein and placebo groups (65% vs 45%, P = .20). However, treatment response acco …
Efficacy and safety of diacerein and celecoxib combination therapy for knee osteoarthritis: A double-blind, randomized, placebo-controlled prospective study.
Youn S, Choi JH, Kim C, Kim SM, Choi WS. Youn S, et al. Medicine (Baltimore). 2023 Sep 29;102(39):e35317. doi: 10.1097/MD.0000000000035317. Medicine (Baltimore). 2023. PMID: 37773836 Free PMC article. Clinical Trial.
In this study, we evaluated the efficacy and safety of diacerein and celecoxib combination therapy in patients with osteoarthritis. METHODS: A total of 71 subjects were randomly assigned to group 1 (diacerein and celecoxib), 2 (diacerein and placebo), or 3 (c …
In this study, we evaluated the efficacy and safety of diacerein and celecoxib combination therapy in patients with osteoarthritis. M …
Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis.
Kongtharvonskul J, Anothaisintawee T, McEvoy M, Attia J, Woratanarat P, Thakkinstian A. Kongtharvonskul J, et al. Eur J Med Res. 2015 Mar 13;20(1):24. doi: 10.1186/s40001-015-0115-7. Eur J Med Res. 2015. PMID: 25889669 Free PMC article. Review.
Compared to placebo, glucosamine showed a significant improvement with unstandardized mean differences (UMD) in total WOMAC, pain WOMAC, function WOMAC, and Lequesne score of -2.49 (95% confidence interval (CI) -4.14, -0.83), -0.75 (95% CI: -1.18, -0.32), -4.78 (95% CI: -5.96, -3 …
Compared to placebo, glucosamine showed a significant improvement with unstandardized mean differences (UMD) in total WOMAC, pain WOMAC, fun …
Diacerein orphan drug development for epidermolysis bullosa simplex: A phase 2/3 randomized, placebo-controlled, double-blind clinical trial.
Wally V, Hovnanian A, Ly J, Buckova H, Brunner V, Lettner T, Ablinger M, Felder TK, Hofbauer P, Wolkersdorfer M, Lagler FB, Hitzl W, Laimer M, Kitzmüller S, Diem A, Bauer JW. Wally V, et al. J Am Acad Dermatol. 2018 May;78(5):892-901.e7. doi: 10.1016/j.jaad.2018.01.019. Epub 2018 Feb 2. J Am Acad Dermatol. 2018. PMID: 29410318 Free article. Clinical Trial.
METHODS: In a randomized, placebo-controlled, phase 2/3 trial we used a 1% diacerein topical formulation to treat defined skin areas in 17 patients. ...CONCLUSION: This trial provides evidence of the impact of 1% diacerein cream in the treatment of EBS....
METHODS: In a randomized, placebo-controlled, phase 2/3 trial we used a 1% diacerein topical formulation to treat defined skin areas …
56 results