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Year Number of Results
1982 1
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1990 3
1991 3
1992 1
1993 2
1994 1
1995 2
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1997 2
1998 1
1999 1
2000 6
2001 2
2002 8
2003 11
2004 16
2005 26
2006 41
2007 28
2008 41
2009 47
2010 60
2011 57
2012 77
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2015 128
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2020 126
2021 26
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Page 1
Heart Failure With Preserved Ejection Fraction In Perspective.
Pfeffer MA, Shah AM, Borlaug BA. Pfeffer MA, et al. Circ Res. 2019 May 24;124(11):1598-1617. doi: 10.1161/CIRCRESAHA.119.313572. Circ Res. 2019. PMID: 31120821 Free PMC article. Review.
Approximately half of the patients with signs and symptoms of heart failure have a left ventricular ejection fraction that is not markedly abnormal. ...The recognition of the magnitude of the problem of heart failure with preserved
Approximately half of the patients with signs and symptoms of heart failure have a left ventricular ejection fractio
Heart Failure with Preserved Ejection Fraction: Diagnosis and Management.
Gazewood JD, Turner PL. Gazewood JD, et al. Am Fam Physician. 2017 Nov 1;96(9):582-588. Am Fam Physician. 2017. PMID: 29094875 Free article. Review.
Heart failure with preserved ejection fraction, also referred to as diastolic heart failure, causes almost one-half of the 5 million cases of heart failure in the United States. ...Measurement of natriuretic pe
Heart failure with preserved ejection fraction, also referred to as diastolic heart fail
Heart failure with preserved ejection fraction: New approaches to diagnosis and management.
Upadhya B, Kitzman DW. Upadhya B, et al. Clin Cardiol. 2020 Feb;43(2):145-155. doi: 10.1002/clc.23321. Epub 2019 Dec 26. Clin Cardiol. 2020. PMID: 31880340 Free PMC article. Review.
The majority of older patients who develop heart failure (HF), particularly older women, have a preserved left ventricular ejection fraction (HFpEF). ...Originally viewed as a disorder due solely to abnormalities in left ventricular (LV) dias
The majority of older patients who develop heart failure (HF), particularly older women, have a preserved left ventricu …
The pathophysiology of heart failure with preserved ejection fraction.
Borlaug BA. Borlaug BA. Nat Rev Cardiol. 2014 Sep;11(9):507-15. doi: 10.1038/nrcardio.2014.83. Epub 2014 Jun 24. Nat Rev Cardiol. 2014. PMID: 24958077 Review.
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF) and, as life expectancies continue to increase in western societies, the prevalence of HFpEF will continue to grow. In contrast to heart fai
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF) and, as li …
Mechanisms, diagnosis, and treatment of heart failure with preserved ejection fraction and diastolic dysfunction.
Plitt GD, Spring JT, Moulton MJ, Agrawal DK. Plitt GD, et al. Expert Rev Cardiovasc Ther. 2018 Aug;16(8):579-589. doi: 10.1080/14779072.2018.1497485. Epub 2018 Jul 16. Expert Rev Cardiovasc Ther. 2018. PMID: 29976104 Free PMC article. Review.
Heart failure with preserved ejection fraction (HFpEF) continues to be a major challenge for clinicians. ...In addition, the confusion of similar terms with HFpEF, such as diastolic heart failure, and diastolic dys
Heart failure with preserved ejection fraction (HFpEF) continues to be a major challenge for clinicians.
Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction: Understanding Mechanisms by Using Noninvasive Methods.
Obokata M, Reddy YNV, Borlaug BA. Obokata M, et al. JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 2):245-257. doi: 10.1016/j.jcmg.2018.12.034. Epub 2019 Jun 12. JACC Cardiovasc Imaging. 2020. PMID: 31202759 Free PMC article. Review.
Research in the last decade has substantially advanced our understanding of the pathophysiology of heart failure with preserved ejection fraction (HFpEF). However, treatment options remain limited as clinical trials have largely failed to identi …
Research in the last decade has substantially advanced our understanding of the pathophysiology of heart failure with prese
Evaluation and management of heart failure with preserved ejection fraction.
Borlaug BA. Borlaug BA. Nat Rev Cardiol. 2020 Sep;17(9):559-573. doi: 10.1038/s41569-020-0363-2. Epub 2020 Mar 30. Nat Rev Cardiol. 2020. PMID: 32231333 Review.
Heart failure with preserved ejection fraction (HFpEF) has grown to become the dominant form of heart failure worldwide, in tandem with ageing of the general population and the increasing prevalences of obesity, diabetes mellitus a
Heart failure with preserved ejection fraction (HFpEF) has grown to become the dominant form of heart
Heart Failure with Preserved Ejection Fraction: Diagnosis and Management.
Oren O, Goldberg S. Oren O, et al. Am J Med. 2017 May;130(5):510-516. doi: 10.1016/j.amjmed.2016.12.031. Epub 2017 Feb 3. Am J Med. 2017. PMID: 28163048 Review.
Heart failure with preserved ejection fraction (HFpEF) is a prevalent condition with substantial individual and societal burden. In this article, we review the current status of understanding of HFpEF, focusing on the challenges and uncertaintie
Heart failure with preserved ejection fraction (HFpEF) is a prevalent condition with substantial individu
Echocardiographic Features of Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction.
Shah AM, Cikes M, Prasad N, Li G, Getchevski S, Claggett B, Rizkala A, Lukashevich I, O'Meara E, Ryan JJ, Shah SJ, Mullens W, Zile MR, Lam CSP, McMurray JJV, Solomon SD; PARAGON-HF Investigators. Shah AM, et al. J Am Coll Cardiol. 2019 Dec 10;74(23):2858-2873. doi: 10.1016/j.jacc.2019.09.063. J Am Coll Cardiol. 2019. PMID: 31806129 Free article. Clinical Trial.
BACKGROUND: The PARAGON-HF (Prospective Comparison of ARNI With ARB Global Outcomes in HF With Preserved Ejection Fraction) trial tested the efficacy of sacubitril-valsartan in patients with heart failure with preserved ejection
BACKGROUND: The PARAGON-HF (Prospective Comparison of ARNI With ARB Global Outcomes in HF With Preserved Ejection Fraction
Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis.
Zheng SL, Chan FT, Nabeebaccus AA, Shah AM, McDonagh T, Okonko DO, Ayis S. Zheng SL, et al. Heart. 2018 Mar;104(5):407-415. doi: 10.1136/heartjnl-2017-311652. Epub 2017 Aug 5. Heart. 2018. PMID: 28780577 Free PMC article. Review.
BACKGROUND: Clinical drug trials in patients with heart failure and preserved ejection fraction have failed to demonstrate improvements in mortality. ...Similar results were observed for cardiovascular mortality. No single drug class reduced …
BACKGROUND: Clinical drug trials in patients with heart failure and preserved ejection fraction have fail …
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