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Page 1
Critical illness-associated diaphragm weakness.
Dres M, Goligher EC, Heunks LMA, Brochard LJ. Dres M, et al. Intensive Care Med. 2017 Oct;43(10):1441-1452. doi: 10.1007/s00134-017-4928-4. Epub 2017 Sep 15. Intensive Care Med. 2017. PMID: 28917004 Review.
Several risk factors for diaphragm weakness have been identified; among them sepsis and mechanical ventilation play central roles. We employ the term critical illness-associated diaphragm weakness to refer to the collective effects of all mechanisms of …
Several risk factors for diaphragm weakness have been identified; among them sepsis and mechanical ventilation play central ro …
Monitoring diaphragm function in the ICU.
Dres M, Demoule A. Dres M, et al. Curr Opin Crit Care. 2020 Feb;26(1):18-25. doi: 10.1097/MCC.0000000000000682. Curr Opin Crit Care. 2020. PMID: 31876624 Free article. Review.
RECENT FINDINGS: Diaphragm weakness, a consequence of diaphragm dysfunction and atrophy, is common in the ICU and associated with serious clinical consequences. ...Diaphragm ultrasound can also be used to evaluate diaphragm muscle stiffness by m …
RECENT FINDINGS: Diaphragm weakness, a consequence of diaphragm dysfunction and atrophy, is common in the ICU and assoc …
Diaphragm Dysfunction in Critical Illness.
Supinski GS, Morris PE, Dhar S, Callahan LA. Supinski GS, et al. Chest. 2018 Apr;153(4):1040-1051. doi: 10.1016/j.chest.2017.08.1157. Epub 2017 Sep 5. Chest. 2018. PMID: 28887062 Free PMC article. Review.
The diaphragm is the major muscle of inspiration, and its function is critical for optimal respiration. ...In these patients, diaphragm weakness is thought to develop from disuse secondary to ventilator-induced diaphragm inactivity and as a consequence …
The diaphragm is the major muscle of inspiration, and its function is critical for optimal respiration. ...In these patients, diap
Diaphragm contractile weakness due to reduced mechanical loading: role of titin.
van der Pijl RJ, Granzier HL, Ottenheijm CAC. van der Pijl RJ, et al. Am J Physiol Cell Physiol. 2019 Aug 1;317(2):C167-C176. doi: 10.1152/ajpcell.00509.2018. Epub 2019 May 1. Am J Physiol Cell Physiol. 2019. PMID: 31042425 Free PMC article. Review.
Only during controlled mechanical ventilation, as occurs during thoracic surgery and in the intensive care unit, is mechanical loading of the diaphragm arrested. Animal studies indicate that the diaphragm is highly sensitive to unloading, causing rapid muscle fiber …
Only during controlled mechanical ventilation, as occurs during thoracic surgery and in the intensive care unit, is mechanical loading of th …
Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort.
Goligher EC, Jonkman AH, Dianti J, Vaporidi K, Beitler JR, Patel BK, Yoshida T, Jaber S, Dres M, Mauri T, Bellani G, Demoule A, Brochard L, Heunks L. Goligher EC, et al. Intensive Care Med. 2020 Dec;46(12):2314-2326. doi: 10.1007/s00134-020-06288-9. Epub 2020 Nov 2. Intensive Care Med. 2020. PMID: 33140181 Free PMC article. Review.
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm develops atrophy as a consequence of low respiratory effort and injury in case of exce …
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mecha …
Coexistence and Impact of Limb Muscle and Diaphragm Weakness at Time of Liberation from Mechanical Ventilation in Medical Intensive Care Unit Patients.
Dres M, Dubé BP, Mayaux J, Delemazure J, Reuter D, Brochard L, Similowski T, Demoule A. Dres M, et al. Am J Respir Crit Care Med. 2017 Jan 1;195(1):57-66. doi: 10.1164/rccm.201602-0367OC. Am J Respir Crit Care Med. 2017. PMID: 27310484
Limb muscle weakness was defined as a Medical Research Council (MRC) score less than 48. MEASUREMENTS AND MAIN RESULTS: Seventy-six patients were assessed at their first spontaneous breathing trial: 63% had diaphragm dysfunction, 34% had limb muscle weakness, …
Limb muscle weakness was defined as a Medical Research Council (MRC) score less than 48. MEASUREMENTS AND MAIN RESULTS: Seventy-six p …
Intensive care unit-acquired weakness: unanswered questions and targets for future research.
Piva S, Fagoni N, Latronico N. Piva S, et al. F1000Res. 2019 Apr 17;8:F1000 Faculty Rev-508. doi: 10.12688/f1000research.17376.1. eCollection 2019. F1000Res. 2019. PMID: 31069055 Free PMC article. Review.
Intensive care unit-acquired weakness (ICU-AW) is the most common neuromuscular impairment in critically ill patients. ...Diagnosis of ICU-AW is clinical and is based on Medical Research Council sum score and handgrip dynamometry for limb weakness and recognition of …
Intensive care unit-acquired weakness (ICU-AW) is the most common neuromuscular impairment in critically ill patients. ...Diagnosis o …
Imaging of the diaphragm: anatomy and function.
Nason LK, Walker CM, McNeeley MF, Burivong W, Fligner CL, Godwin JD. Nason LK, et al. Radiographics. 2012 Mar-Apr;32(2):E51-70. doi: 10.1148/rg.322115127. Radiographics. 2012. PMID: 22411950 Review.
The diaphragm is the primary muscle of ventilation. Dysfunction of the diaphragm is an underappreciated cause of respiratory difficulties and may be due to a wide variety of entities, including surgery, trauma, tumor, and infection. ...Diaphragmatic weakness
The diaphragm is the primary muscle of ventilation. Dysfunction of the diaphragm is an underappreciated cause of respiratory d …
Assessing Diaphragmatic Function.
Schepens T, Fard S, Goligher EC. Schepens T, et al. Respir Care. 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. Respir Care. 2020. PMID: 32457172 Review.
The diaphragm is vulnerable to injury during mechanical ventilation, and diaphragm dysfunction is both a marker of severity of illness and a predictor of poor patient outcome in the ICU. A combination of factors can result in diaphragm weakness. Both i …
The diaphragm is vulnerable to injury during mechanical ventilation, and diaphragm dysfunction is both a marker of severity of …
Diaphragm plasticity in aging and disease: therapies for muscle weakness go from strength to strength.
Greising SM, Ottenheijm CAC, O'Halloran KD, Barreiro E. Greising SM, et al. J Appl Physiol (1985). 2018 Aug 1;125(2):243-253. doi: 10.1152/japplphysiol.01059.2017. Epub 2018 Apr 19. J Appl Physiol (1985). 2018. PMID: 29672230 Free PMC article. Review.
The diaphragm is the main inspiratory muscle and is required to be highly active throughout the life span. ...Throughout the life span various circumstances and conditions may affect the ability of the diaphragm muscle to generate requisite forces, and in turn the …
The diaphragm is the main inspiratory muscle and is required to be highly active throughout the life span. ...Throughout the life spa …
1,213 results