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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1993 5
1994 2
1995 2
1996 6
1997 7
1998 4
1999 11
2000 12
2001 18
2002 30
2003 54
2004 75
2005 112
2006 151
2007 169
2008 227
2009 234
2010 308
2011 312
2012 388
2013 377
2014 392
2015 404
2016 362
2017 391
2018 355
2019 352
2020 376
2021 37
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4,640 results
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Page 1
DICER1 mutations in familial pleuropulmonary blastoma.
Hill DA, Ivanovich J, Priest JR, Gurnett CA, Dehner LP, Desruisseau D, Jarzembowski JA, Wikenheiser-Brokamp KA, Suarez BK, Whelan AJ, Williams G, Bracamontes D, Messinger Y, Goodfellow PJ. Hill DA, et al. Science. 2009 Aug 21;325(5943):965. doi: 10.1126/science.1174334. Epub 2009 Jun 25. Science. 2009. PMID: 19556464 Free PMC article.
Pleuropulmonary blastoma (PPB) is a rare pediatric lung tumor that is often part of an inherited cancer syndrome. ...Expression of DICER1 protein was undetectable in the epithelial component of PPB tumors but was retained in the malignant mesenchyme (sarcoma)
Pleuropulmonary blastoma (PPB) is a rare pediatric lung tumor that is often part of an inherited cancer syndrome. ...Expressio
Congenital pulmonary airway malformations: state-of-the-art review for pediatrician's use.
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S. Leblanc C, et al. Eur J Pediatr. 2017 Dec;176(12):1559-1571. doi: 10.1007/s00431-017-3032-7. Epub 2017 Oct 19. Eur J Pediatr. 2017. PMID: 29046943 Review.
The aim of this "state-of-the-art" review is to cover the recently published literature on CPAM management whether the pulmonary lesion was detected during pregnancy or after birth, the current indications of surgery or surveillance and finally its potential evolution to pleuro-p …
The aim of this "state-of-the-art" review is to cover the recently published literature on CPAM management whether the pulmonary lesion was …
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, Schneider DT, Malkin D, Dehner LP, Messinger YH, Hill DA. Schultz KAP, et al. Clin Cancer Res. 2018 May 15;24(10):2251-2261. doi: 10.1158/1078-0432.CCR-17-3089. Epub 2018 Jan 17. Clin Cancer Res. 2018. PMID: 29343557 Free PMC article. Review.
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Sertoli-Leydig cell tumor, individuals with pathogenic germline DICER1 variants may also develop lung cysts, cystic nephroma, …
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, parti …
Pleuropulmonary Blastoma.
Mlika M, Anjum F, El Mezni F. Mlika M, et al. 2020 Dec 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. StatPearls. 2020 Jan–. PMID: 30480950 Free Books & Documents. Review.
Childhood tumors of the lung are rare malignant tumors accounting for 0.5% to 1% of all primary malignant lung tumors. These tumors are subdivided into 3 subtypes: pulmonary blastoma, fetal adenocarcinoma, and pleuropulmonary blastoma (PPB). ...A malignant im …
Childhood tumors of the lung are rare malignant tumors accounting for 0.5% to 1% of all primary malignant lung tumors. These tumors are subd …
Wilms tumor, pleuropulmonary blastoma, and DICER1: case report and literature review.
Abbo O, Pinnagoda K, Brouchet L, Leobon B, Savagner F, Oliver I, Galinier P, Castex MP, Pasquet M. Abbo O, et al. World J Surg Oncol. 2018 Aug 10;16(1):164. doi: 10.1186/s12957-018-1469-4. World J Surg Oncol. 2018. PMID: 30097050 Free PMC article. Review.
However, if DICER 1 anomalies have been reported in patients with Wilms tumor (WT), to date, no cases of PPB, WT, and DICER1 mutations have been reported in the same patient. ...During his clinical course, the diagnosis of a PPB was made after detecting the DICER
However, if DICER 1 anomalies have been reported in patients with Wilms tumor (WT), to date, no cases of PPB, WT, and DICER1 m …
DICER1 Syndrome: DICER1 Mutations in Rare Cancers.
Robertson JC, Jorcyk CL, Oxford JT. Robertson JC, et al. Cancers (Basel). 2018 May 15;10(5):143. doi: 10.3390/cancers10050143. Cancers (Basel). 2018. PMID: 29762508 Free PMC article. Review.
Through mutations of the gene encoding the endoribonuclease, Dicer, DICER1 syndrome disrupts the biogenesis and processing of miRNAs with subsequent disruption in control of gene expression. Since the first description of DICER1 syndrome, case reports have do …
Through mutations of the gene encoding the endoribonuclease, Dicer, DICER1 syndrome disrupts the biogenesis and processing of …
Imaging of DICER1 syndrome.
Guillerman RP, Foulkes WD, Priest JR. Guillerman RP, et al. Pediatr Radiol. 2019 Oct;49(11):1488-1505. doi: 10.1007/s00247-019-04429-x. Epub 2019 Oct 16. Pediatr Radiol. 2019. PMID: 31620849 Review.
DICER1 syndrome is a highly pleiotropic tumor predisposition syndrome that has been increasingly recognized in the last 10 years. ...The hallmarks of DICER1 syndrome are certain rare tumors including pleuropulmonary blastoma; cystic nephroma; ovarian S
DICER1 syndrome is a highly pleiotropic tumor predisposition syndrome that has been increasingly recognized in the last 10 years. ...
Pleuropulmonary Blastoma: More Than a Lung Neoplasm of Childhood.
Dehner LP, Schultz KA, Hill DA. Dehner LP, et al. Mo Med. 2019 May-Jun;116(3):206-210. Mo Med. 2019. PMID: 31527943 Free PMC article.
Pleuropulmonary blastoma (PPB), the most common primary malignant neoplasm of the lung in childhood, occurs in the same early age group (0-6 years) as the other more common solid tumors such as neuroblastoma and Wilms tumor. ...The other notable finding from our stu
Pleuropulmonary blastoma (PPB), the most common primary malignant neoplasm of the lung in childhood, occurs in the same early
Molecular mechanisms of Dicer: endonuclease and enzymatic activity.
Song MS, Rossi JJ. Song MS, et al. Biochem J. 2017 May 4;474(10):1603-1618. doi: 10.1042/BCJ20160759. Biochem J. 2017. PMID: 28473628 Free PMC article. Review.
The enzyme Dicer is best known for its role as a riboendonuclease in the small RNA pathway. ...This review will describe the canonical and newly identified functions of Dicer....
The enzyme Dicer is best known for its role as a riboendonuclease in the small RNA pathway. ...This review will describe the canonica …
An update on the central nervous system manifestations of DICER1 syndrome.
de Kock L, Priest JR, Foulkes WD, Alexandrescu S. de Kock L, et al. Acta Neuropathol. 2020 Apr;139(4):689-701. doi: 10.1007/s00401-019-01997-y. Epub 2019 Apr 5. Acta Neuropathol. 2020. PMID: 30953130 Review.
Pleuropulmonary blastoma (PPB), the most common primary lung cancer in children, is the hallmark tumor of the syndrome. ...Several central nervous system (CNS) manifestations have also been defined, including metastases of PPB to the cerebrum, pituitary blastoma
Pleuropulmonary blastoma (PPB), the most common primary lung cancer in children, is the hallmark tumor of the syndrome. ...Sev
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