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Year Number of Results
1981 1
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2,897 results

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Page 1
Dihydroartemisinin: A Potential Natural Anticancer Drug.
Dai X, Zhang X, Chen W, Chen Y, Zhang Q, Mo S, Lu J. Dai X, et al. Int J Biol Sci. 2021 Jan 16;17(2):603-622. doi: 10.7150/ijbs.50364. eCollection 2021. Int J Biol Sci. 2021. PMID: 33613116 Free PMC article. Review.
Dihydroartemisinin (DHA) is an active metabolite of artemisinin and its derivatives (ARTs), and it is an effective clinical drug widely used to treat malaria. ...
Dihydroartemisinin (DHA) is an active metabolite of artemisinin and its derivatives (ARTs), and it is an effective clinical drug wide …
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
Qiu P, Chang Y, Chen X, Wang S, Nie H, Hong Y, Zhang M, Wang H, Xiao C, Chen Y, Liu L, Zhao Q. Qiu P, et al. Adv Sci (Weinh). 2024 Sep;11(35):e2403461. doi: 10.1002/advs.202403461. Epub 2024 Jul 11. Adv Sci (Weinh). 2024. PMID: 38992955 Free PMC article.
The precise mechanism underlying the therapeutic effects of dihydroartemisinin (DHA) in alleviating colitis remains incompletely understood. A strong correlation existed between the elevation of glial fibrillary acidic protein (GFAP)(+)/S100 calcium binding protein B (S100 …
The precise mechanism underlying the therapeutic effects of dihydroartemisinin (DHA) in alleviating colitis remains incompletely unde …
Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3beta/TCF7/MMP9 pathway and synergies with capecitabine.
Dai X, Chen W, Qiao Y, Chen X, Chen Y, Zhang K, Zhang Q, Duan X, Li X, Zhao J, Tian F, Liu K, Dong Z, Lu J. Dai X, et al. Cancer Lett. 2024 Feb 1;582:216596. doi: 10.1016/j.canlet.2023.216596. Epub 2023 Dec 13. Cancer Lett. 2024. PMID: 38101610
Patients with colorectal cancer (CRC) suffer from poor prognosis and lack effective drugs. Dihydroartemisinin (DHA) has anti-cancer potential but the mechanism remains unclear. We elucidated the effects and mechanism of DHA on CRC development with the aim of providing an e …
Patients with colorectal cancer (CRC) suffer from poor prognosis and lack effective drugs. Dihydroartemisinin (DHA) has anti-cancer p …
Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malaria.
Keating GM. Keating GM. Drugs. 2012 May 7;72(7):937-61. doi: 10.2165/11203910-000000000-00000. Drugs. 2012. PMID: 22515619 Review.
One such combination comprises the artemisinin derivative dihydroartemisinin and the bisquinolone piperaquine. Eurartesim is the only dihydroartemisinin/piperaquine formulation that meets international good manufacturing practice standards. This article reviews the …
One such combination comprises the artemisinin derivative dihydroartemisinin and the bisquinolone piperaquine. Eurartesim is the onl …
Exploring combinations of dihydroartemisinin for cancer therapy: A comprehensive review.
Rani K, Chand Sahu R, Chaudhuri A, Kumar DN, Arora S, Kumar D, Agrawal AK. Rani K, et al. Biochem Biophys Res Commun. 2025 Jun 8;765:151854. doi: 10.1016/j.bbrc.2025.151854. Epub 2025 Apr 18. Biochem Biophys Res Commun. 2025. PMID: 40262468 Review.
While advancements in research have improved outcomes for many cancer patients, treatments for specific tumor types still face limitations. Dihydroartemisinin (DHA), an active metabolite of artemisinin and its derivatives, has proven to be an effective anti-malarial agent. …
While advancements in research have improved outcomes for many cancer patients, treatments for specific tumor types still face limitations. …
Dihydroartemisinin attenuates ischemia/reperfusion-induced renal tubular senescence by activating autophagy.
Liu H, Huang Z, Jiang H, Su K, Si Z, Wu W, Wang H, Li D, Tan N, Zhang Z. Liu H, et al. Chin J Nat Med. 2023 Sep;21(9):682-693. doi: 10.1016/S1875-5364(23)60398-X. Chin J Nat Med. 2023. PMID: 37777318
Acute kidney injury (AKI) is an important factor for the occurrence and development of CKD. The protective effect of dihydroartemisinin on AKI and and reported mechanism have not been reported. In this study, we used two animal models including ischemia-reperfusion and UUO …
Acute kidney injury (AKI) is an important factor for the occurrence and development of CKD. The protective effect of dihydroartemisinin …
Dihydroartemisinin Triggers Ferroptosis in Multidrug-Resistant Leukemia Cells.
Zhang X, Ai Z, Zhang Z, Dong R, Wang L, Jin S, Wei H. Zhang X, et al. DNA Cell Biol. 2022 Aug;41(8):705-715. doi: 10.1089/dna.2021.1145. Epub 2022 Jun 10. DNA Cell Biol. 2022. PMID: 35687364
These elevations might have increased the antioxidant ability of K562/ADM cells and granted them increased buffering capacity against iron disorder, protecting them from ferroptosis and favoring drug resistance. However, dihydroartemisinin (DHA) restrained MDR K562/ADM cel …
These elevations might have increased the antioxidant ability of K562/ADM cells and granted them increased buffering capacity against iron d …
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Zhang XG, Li GX, Zhao SS, Xu FL, Wang YH, Wang W. Zhang XG, et al. Parasitol Res. 2014 May;113(5):1769-73. doi: 10.1007/s00436-014-3822-z. Epub 2014 Mar 8. Parasitol Res. 2014. PMID: 24609234 Review.
However, another artemisinin derivative dihydroartemisinin (DHA) cannot be neglected. Dihydroartemisinin, a derivative of artemisinin with the C-10 lactone group replaced by hemiacetal and the active metabolite of all artemisinin compounds, was firstly identified as …
However, another artemisinin derivative dihydroartemisinin (DHA) cannot be neglected. Dihydroartemisinin, a derivative of arte …
Dihydroartemisinin alleviates morphine-induced neuroinflammation in BV-2 cells.
Guan S, Jin T, Han S, Fan W, Chu H, Liang Y. Guan S, et al. Bioengineered. 2021 Dec;12(2):9401-9410. doi: 10.1080/21655979.2021.1982311. Bioengineered. 2021. PMID: 34854364 Free PMC article.
Morphine tolerance poses a great challenge for clinicians, whose pathogenesis has a close connection with microglial activation and neuroinflammation. Dihydroartemisinin (DHA) that derives from artemisinin, may serve as a potential anti-inflammatory drug. ...
Morphine tolerance poses a great challenge for clinicians, whose pathogenesis has a close connection with microglial activation and neuroinf …
2,897 results