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1992 3
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1998 5
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2001 5
2003 2
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63 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Dihydrocodeine for detoxification and maintenance treatment in individuals with opiate use disorders.
Carney T, Van Hout MC, Norman I, Dada S, Siegfried N, Parry CD. Carney T, et al. Cochrane Database Syst Rev. 2020 Feb 18;2(2):CD012254. doi: 10.1002/14651858.CD012254.pub2. Cochrane Database Syst Rev. 2020. PMID: 32068247 Free PMC article.
BACKGROUND: Medical treatment and detoxification from opiate disorders includes oral administration of opioid agonists. Dihydrocodeine (DHC) substitution treatment is typically low threshold and therefore has the capacity to reach wider groups of opiate users. ...
BACKGROUND: Medical treatment and detoxification from opiate disorders includes oral administration of opioid agonists. Dihydrocodeine …
Dihydrocodeine for breathlessness in "pink puffers".
Johnson MA, Woodcock AA, Geddes DM. Johnson MA, et al. Br Med J (Clin Res Ed). 1983 Feb 26;286(6366):675-7. doi: 10.1136/bmj.286.6366.675. Br Med J (Clin Res Ed). 1983. PMID: 6402199 Free PMC article. Clinical Trial.
During the first two weeks patients were instructed to take dihydrocodeine 15 mg or placebo 30 minutes before exercise as required up to three times daily. During the third week patients received either dihydrocodeine or placebo on alternate days. During the weekly …
During the first two weeks patients were instructed to take dihydrocodeine 15 mg or placebo 30 minutes before exercise as required up …
Cannabis-based medicines for chronic neuropathic pain in adults.
Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W. Mücke M, et al. Cochrane Database Syst Rev. 2018 Mar 7;3(3):CD012182. doi: 10.1002/14651858.CD012182.pub2. Cochrane Database Syst Rev. 2018. PMID: 29513392 Free PMC article.
The studies were 2 to 26 weeks long and compared an oromucosal spray with a plant-derived combination of tetrahydrocannabinol (THC) and cannabidiol (CBD) (10 studies), a synthetic cannabinoid mimicking THC (nabilone) (two studies), inhaled herbal cannabis (two studies) and plant- …
The studies were 2 to 26 weeks long and compared an oromucosal spray with a plant-derived combination of tetrahydrocannabinol (THC) and cann …
A multiple dose comparison of ibuprofen and dihydrocodeine after third molar surgery.
McQuay HJ, Carroll D, Guest PG, Robson S, Wiffen PJ, Juniper RP. McQuay HJ, et al. Br J Oral Maxillofac Surg. 1993 Apr;31(2):95-100. doi: 10.1016/0266-4356(93)90169-w. Br J Oral Maxillofac Surg. 1993. PMID: 8471588 Clinical Trial.
The results showed that ibuprofen produced significantly greater analgesia than either of the dihydrocodeine treatments on the day of surgery. Ibuprofen and dihydrocodeine 60 mg produced significantly greater analgesia than dihydrocodeine 30 mg on the day aft …
The results showed that ibuprofen produced significantly greater analgesia than either of the dihydrocodeine treatments on the day of …
The role of active metabolites in dihydrocodeine effects.
Schmidt H, Vormfelde SV, Walchner-Bonjean M, Klinder K, Freudenthaler S, Gleiter CH, Gundert-Remy U, Skopp G, Aderjan R, Fuhr U. Schmidt H, et al. Int J Clin Pharmacol Ther. 2003 Mar;41(3):95-106. doi: 10.5414/cpp41095. Int J Clin Pharmacol Ther. 2003. PMID: 12665158 Clinical Trial.
OBJECTIVE: The metabolism of dihydrocodeine to dihydromorphine, a high affinity mu-opioid receptor ligand in membrane homogenates, is catalyzed by CYP2D6. However, it is not clear whether an active CYP2D6 enzyme is required for opioid receptor-mediated effects in man after …
OBJECTIVE: The metabolism of dihydrocodeine to dihydromorphine, a high affinity mu-opioid receptor ligand in membrane homogenates, is …
Saliva testing after single and chronic administration of dihydrocodeine.
Skopp G, Pötsch L, Klinder K, Richter B, Aderjan R, Mattern R. Skopp G, et al. Int J Legal Med. 2001;114(3):133-40. doi: 10.1007/pl00007717. Int J Legal Med. 2001. PMID: 11296884 Clinical Trial.
In the first investigation, blood and saliva were collected periodically from six subjects after oral administration of 60 mg dihydrocodeine. In the second study, 20 subjects on oral dihydrocodeine maintenance provided single samples of blood and saliva simultaneous …
In the first investigation, blood and saliva were collected periodically from six subjects after oral administration of 60 mg dihydrocode …
Effects of dihydrocodeine on chemosensitivity and exercise tolerance in patients with chronic heart failure.
Chua TP, Harrington D, Ponikowski P, Webb-Peploe K, Poole-Wilson PA, Coats AJ. Chua TP, et al. J Am Coll Cardiol. 1997 Jan;29(1):147-52. doi: 10.1016/s0735-1097(96)00446-9. J Am Coll Cardiol. 1997. PMID: 8996307 Free article. Clinical Trial.
OBJECTIVES: We sought to test the hypothesis that suppression of chemosensitivity (respiratory response to arterial blood gases) with dihydrocodeine may improve dyspnea and exercise tolerance in patients with chronic heart failure. ...Its suppression with dihydrocodeine …
OBJECTIVES: We sought to test the hypothesis that suppression of chemosensitivity (respiratory response to arterial blood gases) with dih …
The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor metabolizers.
Wilder-Smith CH, Hufschmid E, Thormann W. Wilder-Smith CH, et al. Br J Clin Pharmacol. 1998 Jun;45(6):575-81. doi: 10.1046/j.1365-2125.1998.00727.x. Br J Clin Pharmacol. 1998. PMID: 9663813 Free PMC article. Clinical Trial.
The aim of this study was to assess the importance of the dihydromorphine metabolites of dihydrocodeine in analgesia by investigating the effects of dihydrocodeine on somatic and visceral pain thresholds in extensive and quinidine-induced poor metabolizers. ...Preme …
The aim of this study was to assess the importance of the dihydromorphine metabolites of dihydrocodeine in analgesia by investigating …
Comparison of flupirtine maleate and dihydrocodeine in patients following surgery.
Moore RA, Bullingham RE, Simpson S, O'Sullivan G, Evans PJ, McQuay HJ, Lloyd JW. Moore RA, et al. Br J Anaesth. 1983 May;55(5):429-32. doi: 10.1093/bja/55.5.429. Br J Anaesth. 1983. PMID: 6342637 Free article. Clinical Trial.
Flupirtine maleate 100 mg was compared with dihydrocodeine 60 mg when given by mouth to 50 women on the first 3 days following abdominal hysterectomy in a double-blind parallel-group trial. ...The only significant differences in side-effects were an increased frequency of …
Flupirtine maleate 100 mg was compared with dihydrocodeine 60 mg when given by mouth to 50 women on the first 3 days following abdomi …
Analgesic effects of dihydrocodeine and tramadol when administered either in the morning or evening.
Hummel T, Kraetsch HG, Lötsch J, Hepper M, Liefhold J, Kobal G. Hummel T, et al. Chronobiol Int. 1995 Feb;12(1):62-72. doi: 10.3109/07420529509064501. Chronobiol Int. 1995. PMID: 7750159 Clinical Trial.
The aim of the study was to investigate the analgesic effects of two opioids [dihydrocodeine (DHC) and tramadol] when administered either in the morning or evening. The experimental technique used is based on chemosomatosensory event-related potentials (CSSERPs) in respons …
The aim of the study was to investigate the analgesic effects of two opioids [dihydrocodeine (DHC) and tramadol] when administered ei …
63 results