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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1957 1
1962 2
1965 1
1966 1
1975 2
1976 1
1978 2
1987 2
1989 1
1991 1
1992 2
1993 2
1994 1
1995 5
1996 3
1998 3
1999 7
2000 3
2001 9
2002 7
2003 12
2004 17
2005 24
2006 24
2007 21
2008 24
2009 38
2010 31
2011 32
2012 42
2013 46
2014 39
2015 51
2016 49
2017 50
2018 37
2019 33
2020 27
2021 2
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591 results
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Page 1
Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.
Thomson CA, Ho E, Strom MB. Thomson CA, et al. Nutr Rev. 2016 Jul;74(7):432-43. doi: 10.1093/nutrit/nuw010. Epub 2016 May 31. Nutr Rev. 2016. PMID: 27261275 Free PMC article. Review.
The role of bioactive compounds of food origin, including those found in cruciferous vegetables, is an active area of research in cancer chemoprevention. This review focuses on 3,3'-diindolylmethane (DIM), the major bioactive indole in crucifers. ...
The role of bioactive compounds of food origin, including those found in cruciferous vegetables, is an active area of research in cancer che …
Retraction: 3, 3'-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process.
PLOS ONE Editors. PLOS ONE Editors. PLoS One. 2020 Feb 6;15(2):e0229164. doi: 10.1371/journal.pone.0229164. eCollection 2020. PLoS One. 2020. PMID: 32027724 Free PMC article. No abstract available.
Retraction: 3,3'-Diindolylmethane Enhances Chemosensitivity of Multiple Chemotherapeutic Agents in Pancreatic Cancer.
[No authors listed] [No authors listed] Cancer Res. 2018 Sep 15;78(18):5467. doi: 10.1158/0008-5472.CAN-18-1176. Cancer Res. 2018. PMID: 30217877 Free PMC article. No abstract available.
Comparison of dienogest effects upon 3,3'-diindolylmethane supplementation in models of endometriosis and clinical cases.
Morales-Prieto DM, Herrmann J, Osterwald H, Kochhar PS, Schleussner E, Markert UR, Oettel M. Morales-Prieto DM, et al. Reprod Biol. 2018 Sep;18(3):252-258. doi: 10.1016/j.repbio.2018.07.002. Epub 2018 Jul 9. Reprod Biol. 2018. PMID: 30001982 Clinical Trial.
Changes in diet, mainly to vegetable consumption, are beneficial in the treatment of estrogen-related pathologies but their use for endometriosis has been poorly studied. In this study, addition of the phytochemical 3,3'-diindolylmethane (DIM) to DNG therapy …
Changes in diet, mainly to vegetable consumption, are beneficial in the treatment of estrogen-related pathologies but their use for endometr …
A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.
Thomson CA, Chow HHS, Wertheim BC, Roe DJ, Stopeck A, Maskarinec G, Altbach M, Chalasani P, Huang C, Strom MB, Galons JP, Thompson PA. Thomson CA, et al. Breast Cancer Res Treat. 2017 Aug;165(1):97-107. doi: 10.1007/s10549-017-4292-7. Epub 2017 May 30. Breast Cancer Res Treat. 2017. PMID: 28560655 Free PMC article. Clinical Trial.
PURPOSE: Diindolylmethane (DIM), a bioactive metabolite of indole-3-carbinol found in cruciferous vegetables, has proposed cancer chemoprevention activity in the breast. ...RESULTS: Ninety-eight women (51 placebo, 47 DIM) completed intervention; compliance with trea …
PURPOSE: Diindolylmethane (DIM), a bioactive metabolite of indole-3-carbinol found in cruciferous vegetables, has proposed can …
3,3'-Diindolylmethane alleviates acute atopic dermatitis by regulating T cell differentiation in a mouse model.
Wu X, Liu J, Chen C, Huang Z, Zang Y, Chen J, Dong L, Zhang J, Ding Z. Wu X, et al. Mol Immunol. 2020 Dec 10:S0161-5890(20)30543-5. doi: 10.1016/j.molimm.2020.11.013. Online ahead of print. Mol Immunol. 2020. PMID: 33309306
After intraperitoneal injection of 3,3'-diindolylmethane, skin erythema and edema in mice were significantly alleviated. Furthermore, 3,3'-diindolylmethane reduced immune activation, probably by inhibiting the secretion of thymic stromal …
After intraperitoneal injection of 3,3'-diindolylmethane, skin erythema and edema in mice were significantly alleviated …
General Synthesis of Unsymmetrical 3,3'-(Aza)diindolylmethane Derivatives.
Pillaiyar T, Gorska E, Schnakenburg G, Müller CE. Pillaiyar T, et al. J Org Chem. 2018 Sep 7;83(17):9902-9913. doi: 10.1021/acs.joc.8b01349. Epub 2018 Jul 31. J Org Chem. 2018. PMID: 30025207
Diindolylmethane (DIM) and its derivatives have recently been in the focus of interest due to their significant biological activities, specifically in cancer prevention and therapy. ...In the present study we developed a new, mild and efficient access to unsymmetrically su
Diindolylmethane (DIM) and its derivatives have recently been in the focus of interest due to their significant biological activities
Targeting the Microcirculation by Indole-3-carbinol and Its Main Derivate 3,3,'-diindolylmethane: Effects on Angiogenesis, Thrombosis and Inflammation.
Ampofo E, Schmitt BM, Menger MD, Laschke MW. Ampofo E, et al. Mini Rev Med Chem. 2018;18(11):962-968. doi: 10.2174/1389557518666180313100144. Mini Rev Med Chem. 2018. PMID: 29532757 Review.
The pharmacological targeting of microcirculatory dysregulations is a therapeutic strategy for the treatment of numerous pathological conditions, such as cancer, thrombosis and inflammation. A promising candidate for this purpose is indole-3-carbinol (I3C), a phytochemical …
The pharmacological targeting of microcirculatory dysregulations is a therapeutic strategy for the treatment of numerous pathological condit …
Retraction: Apoptosis-Inducing Effect of Erlotinib Is Potentiated by 3,3'-Diindolylmethane In Vitro and In Vivo Using an Orthotopic Model of Pancreatic Cancer.
[No authors listed] [No authors listed] Mol Cancer Ther. 2018 Oct;17(10):2266. doi: 10.1158/1535-7163.MCT-18-0522. Mol Cancer Ther. 2018. PMID: 30275271 Free PMC article. No abstract available.
3,3'-Diindolylmethane nanoencapsulation improves its antinociceptive action: Physicochemical and behavioral studies.
Mattiazzi J, Marcondes Sari MH, Brum TB, Araújo PCO, Nadal JM, Farago PV, Nogueira CW, Cruz L. Mattiazzi J, et al. Colloids Surf B Biointerfaces. 2019 Sep 1;181:295-304. doi: 10.1016/j.colsurfb.2019.05.063. Epub 2019 May 25. Colloids Surf B Biointerfaces. 2019. PMID: 31154140
This study aimed to characterize the physicochemical properties of 3,3'-diindolylmethane (DIM)-loaded nanocapsules (NCs) as well as the antinociceptive effect using distinct animal models (hot plate test, formalin-induced nociception and complete Freud's adju …
This study aimed to characterize the physicochemical properties of 3,3'-diindolylmethane (DIM)-loaded nanocapsules (NCs …
591 results
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