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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 1
1977 1
1978 1
1981 1
1982 1
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1987 2
1990 2
1991 4
1992 2
1993 2
1994 4
1996 6
1997 2
1999 2
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42 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy of topical dimetindene in experimentally induced pruritus and weal and flare reactions.
Lever LR, Hill S, Dykes PJ, Marks R. Lever LR, et al. Skin Pharmacol. 1991;4(2):109-12. doi: 10.1159/000210933. Skin Pharmacol. 1991. PMID: 1878244 Clinical Trial.
Treatment of the forearm skin in 20 volunteers resulted in an increase in itch threshold with dimetindene gel compared to placebo. Treatment of the forearm skin with dimetindene gel in 32 volunteers had no significant effect on weal thickness in subjects treated for …
Treatment of the forearm skin in 20 volunteers resulted in an increase in itch threshold with dimetindene gel compared to placebo. Tr …
Evaluation of the local antihistaminic activity of dimetindene maleate by a quantitative method.
Rampini E, Oberhauser V, Nunzi E. Rampini E, et al. Dermatologica. 1978;157(2):105-9. doi: 10.1159/000250814. Dermatologica. 1978. PMID: 27397 Clinical Trial.
The topical application of a 0.1% dimetindene maleate gel on the forearms of 11 subjects reduces the areas of both erythema and wheal produced by the intradermal injection of 0.025 mg of histamine hydrochloride to a statistically greater degree than 1% d-chlorpheniramine m …
The topical application of a 0.1% dimetindene maleate gel on the forearms of 11 subjects reduces the areas of both erythema and wheal …
Pharmacodynamic dose finding of dimetindene in a sustained release formulation.
Horak F, Jäger S, Nirnberger G, Berger U, Andresen L, Vix JM, Rehn D. Horak F, et al. Arzneimittelforschung. 1993 Nov;43(11):1193-5. Arzneimittelforschung. 1993. PMID: 8292063 Clinical Trial.
A sustained release form of dimetindene (dimethindene maleate, Fenistil, CAS 3614-69-5) was developed based on a micropellet technique. ...Therefore 4 mg dimetindene once a day is the adequate treatment for usual pollinotic disease conditions....
A sustained release form of dimetindene (dimethindene maleate, Fenistil, CAS 3614-69-5) was developed based on a micropellet t …
Efficacy and safety of intranasally applied dimetindene maleate solution. Multicenter study in children under 14 years suffering from seasonal allergic rhinitis.
Bauer CP, Unkauf M. Bauer CP, et al. Arzneimittelforschung. 2001;51(3):232-7. doi: 10.1055/s-0031-1300029. Arzneimittelforschung. 2001. PMID: 11304939 Clinical Trial.
Patients were randomised to receive either dimetindene 0.1% (Fenistil Nasal Spray) or a levocabastine (CAS 79516-68-0) 0.05% solution as reference medication. ...A single-blind approach was chosen, because the reference medication levocabastine requires two spray puffs per …
Patients were randomised to receive either dimetindene 0.1% (Fenistil Nasal Spray) or a levocabastine (CAS 79516-68-0) 0.05% solution …
Efficacy and tolerability of intranasally applied dimetindene maleate solution versus placebo in the treatment of seasonal allergic rhinitis.
Horak F, Unkauf M, Beckers C, Mittermaier EM. Horak F, et al. Arzneimittelforschung. 2000 Dec;50(12):1099-105. doi: 10.1055/s-0031-1300341. Arzneimittelforschung. 2000. PMID: 11190775 Clinical Trial.
The aim of this study was to investigate the efficacy and tolerability of a 0.1% dimetindene maleate spray (Fenistil Nasal Dosierspray) compared to placebo when applied intranasally. Dimetindene (dimetindene maleate, CAS 3614-69-5, DMM) is a very potent and w …
The aim of this study was to investigate the efficacy and tolerability of a 0.1% dimetindene maleate spray (Fenistil Nasal Dosierspra …
Evaluation of the local anaesthetic activity of dimetindene maleate by means of laser algesimetry in healthy volunteers.
Schaffler K, Wauschkuhn CH, Brunnauer H, Rehn D. Schaffler K, et al. Arzneimittelforschung. 1992 Nov;42(11):1332-5. Arzneimittelforschung. 1992. PMID: 1492845 Clinical Trial.
Dimetindene maleate (DMM, Fenistil, CAS 3614-69-5) a specific H1-receptor antagonist, is therapeutically used for the treatment of respiratory allergies, urticaria, itching dermatoses and generally pruritic sensations occurring with various diseases. As it exhibits local a …
Dimetindene maleate (DMM, Fenistil, CAS 3614-69-5) a specific H1-receptor antagonist, is therapeutically used for the treatment of re …
Targeted Use of Placebo Effects Decreases Experimental Itch in Atopic Dermatitis Patients: A Randomized Controlled Trial.
Sölle A, Worm M, Benedetti F, Sabine Bartholomäus T, Schwender-Groen L, Klinger R. Sölle A, et al. Clin Pharmacol Ther. 2021 Aug;110(2):486-497. doi: 10.1002/cpt.2276. Epub 2021 May 25. Clin Pharmacol Ther. 2021. PMID: 33894061 Clinical Trial.
Control group 2 received a placebo infusion (saline) declared as dimetindene and also experienced the conditioning experience (PLAC+INST+COND). Itch was experimentally induced with histamine via a skin prick test. ...We conclude that specifically generated targeted placebo …
Control group 2 received a placebo infusion (saline) declared as dimetindene and also experienced the conditioning experience (PLAC+I …
Premedication with H1 and H2 blocking agents reduces the incidence of postoperative nausea and vomiting.
Doenicke AW, Hoernecke R, Celik I. Doenicke AW, et al. Inflamm Res. 2004 Aug;53 Suppl 2:S154-8. doi: 10.1007/s00011-004-0367-0. Epub 2004 Aug 10. Inflamm Res. 2004. PMID: 15338068 Clinical Trial.
Patients in the treatment groups were premedicated with the following H1 + H2 receptor antagonists:Group 1 (n = 335): 5 mg/kg cimetidine i.v. + 0.1 mg/kg dimetindene i.v. 20 min before induction of anaesthesiaGroup 2 (n = 337): 1.25 mg/kg ranitidine i.v. + 0.1 mg/kg dim …
Patients in the treatment groups were premedicated with the following H1 + H2 receptor antagonists:Group 1 (n = 335): 5 mg/kg cimetidine i.v …
Effects of dimethindene maleate nasal spray on the quality of life in seasonal allergic rhinitis.
Kirchhoff CH, Kremer B, Haaf-von Below S, Kyrein HJ, Mösges R. Kirchhoff CH, et al. Rhinology. 2003 Sep;41(3):159-66. Rhinology. 2003. PMID: 14579656 Clinical Trial.
OBJECTIVE: To determine if the H1-receptor antagonist dimethindene maleate (DMM), topically applied, is able to improve the quality of life (QoL) in patients with seasonal allergic rhinitis better than placebo. ...
OBJECTIVE: To determine if the H1-receptor antagonist dimethindene maleate (DMM), topically applied, is able to improve the quality o …
42 results