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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
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1948 2
1949 1
1950 3
1951 1
1952 2
1953 4
1955 2
1956 3
1957 1
1958 4
1959 2
1960 2
1961 4
1962 6
1963 5
1964 5
1965 4
1966 6
1967 8
1968 9
1969 5
1970 4
1971 7
1972 8
1973 10
1974 9
1975 5
1976 13
1977 5
1978 6
1979 10
1980 5
1981 3
1982 6
1983 11
1984 12
1985 13
1986 5
1987 5
1988 6
1989 7
1990 8
1991 8
1992 14
1993 9
1994 7
1995 12
1996 13
1997 7
1998 7
1999 11
2000 12
2001 23
2002 27
2003 37
2004 34
2005 34
2006 45
2007 45
2008 33
2009 52
2010 65
2011 65
2012 77
2013 80
2014 98
2015 102
2016 111
2017 106
2018 117
2019 119
2020 140
2021 156
2022 134
2023 108
2024 1

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1,924 results

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Page 1
Diosgenin: Mechanistic Insights on its Anti-inflammatory Effects.
Karami-Mohajeri S, Mohammadinejad R, Ashrafizadeh M, Mohamadi N, Mohajeri M, Sharififar F. Karami-Mohajeri S, et al. Antiinflamm Antiallergy Agents Med Chem. 2022;21(1):2-9. doi: 10.2174/1871523021666220328121721. Antiinflamm Antiallergy Agents Med Chem. 2022. PMID: 35346012 Review.
Diosgenin (DG), a well-known steroid saponin, has shown anti-inflammatory effects. This review was aimed to discuss all published literature concerning the anti-inflammatory effects of diosgenin. Based on the modulatory impact of DG on the NF-kappaB pathway, its sup
Diosgenin (DG), a well-known steroid saponin, has shown anti-inflammatory effects. This review was aimed to discuss all published lit
Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis.
Wang D, Wang X. Wang D, et al. Drug Des Devel Ther. 2022 Jul 17;16:2305-2323. doi: 10.2147/DDDT.S368836. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35875677 Free PMC article. Review.
Diosgenin and its analogs are widely found in the rhizomes of Dioscore, Solanum, and other species and share similar chemical structures and pharmacological effects. ...However, a review of the effects of diosgenin and its natural structure analogs on AS is still la
Diosgenin and its analogs are widely found in the rhizomes of Dioscore, Solanum, and other species and share similar chemical structu
Diosgenin: An ingress towards solving puzzle for diabetes treatment.
Arya P, Kumar P. Arya P, et al. J Food Biochem. 2022 Dec;46(12):e14390. doi: 10.1111/jfbc.14390. Epub 2022 Sep 15. J Food Biochem. 2022. PMID: 36106684 Review.
The role of diosgenin in curing various metabolic disorders is quite popular from some time. ...Hence diosgenin could be a better way for researchers to develop a method for diabetes treatment....
The role of diosgenin in curing various metabolic disorders is quite popular from some time. ...Hence diosgenin could be a bet …
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives.
Semwal P, Painuli S, Abu-Izneid T, Rauf A, Sharma A, Daştan SD, Kumar M, Alshehri MM, Taheri Y, Das R, Mitra S, Emran TB, Sharifi-Rad J, Calina D, Cho WC. Semwal P, et al. Oxid Med Cell Longev. 2022 May 29;2022:1035441. doi: 10.1155/2022/1035441. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35677108 Free PMC article. Review.
This review aims to provide an overview of the in vitro, in vivo, and clinical studies reporting the diosgenin's pharmacological effects and to discuss the safety issues. ...However, further well-designed clinical trials are needed to address the other effects seen in prec …
This review aims to provide an overview of the in vitro, in vivo, and clinical studies reporting the diosgenin's pharmacological effe …
Diosgenin a steroidal compound: An emerging way to cancer management.
Arya P, Kumar P. Arya P, et al. J Food Biochem. 2021 Dec;45(12):e14005. doi: 10.1111/jfbc.14005. Epub 2021 Nov 19. J Food Biochem. 2021. PMID: 34799857 Review.
Fenugreek is an excellent source of various bioactive compounds especially diosgenin. Diosgenin is steroidal sapogenin that cures various health issues including cancers. ...Cancer cure with diosgenin is providing a new base to the pharmaceutical and medical …
Fenugreek is an excellent source of various bioactive compounds especially diosgenin. Diosgenin is steroidal sapogenin that cu …
Diosgenin attenuates non-alcoholic fatty liver disease in type 2 diabetes through regulating SIRT6-related fatty acid uptake.
Nie K, Gao Y, Chen S, Wang Z, Wang H, Tang Y, Su H, Lu F, Dong H, Fang K. Nie K, et al. Phytomedicine. 2023 Mar;111:154661. doi: 10.1016/j.phymed.2023.154661. Epub 2023 Jan 10. Phytomedicine. 2023. PMID: 36682299 Free article.
PURPOSE: This study aims to figure out the mechanism how diosgenin alleviate NAFLD in T2DM and the relationship with SIRT6. ...The effect of diosgenin could be reversed in DH+OSS group and the same effect was observed in MDL group in the second part of study in vivo …
PURPOSE: This study aims to figure out the mechanism how diosgenin alleviate NAFLD in T2DM and the relationship with SIRT6. ...The ef …
Effects of diosgenin and its derivatives on atherosclerosis.
Wu FC, Jiang JG. Wu FC, et al. Food Funct. 2019 Nov 1;10(11):7022-7036. doi: 10.1039/c9fo00749k. Epub 2019 Nov 5. Food Funct. 2019. PMID: 31687707 Review.
At present, it is an important topic for researchers to develop safe and effective drugs from natural products to prevent and treat cardiovascular diseases. Diosgenin (DSG) is a plant sterol saponin mainly found in natural medicinal plants such as fenugreek seeds and wild …
At present, it is an important topic for researchers to develop safe and effective drugs from natural products to prevent and treat cardiova …
Anticancer Activity of Diosgenin and Its Molecular Mechanism.
Ren QL, Wang Q, Zhang XQ, Wang M, Hu H, Tang JJ, Yang XT, Ran YH, Liu HH, Song ZX, Liu JG, Li XL. Ren QL, et al. Chin J Integr Med. 2023 Aug;29(8):738-749. doi: 10.1007/s11655-023-3693-1. Epub 2023 Mar 20. Chin J Integr Med. 2023. PMID: 36940072 Free PMC article. Review.
Clinical investigations have revealed clinical dosage and safety property of diosgenin. Furthermore, in order to improve the biological activity and bioavailability of diosgenin, this review focuses on the development of diosgenin nano drug carriers, combined …
Clinical investigations have revealed clinical dosage and safety property of diosgenin. Furthermore, in order to improve the biologic …
Dioscin and diosgenin: Insights into their potential protective effects in cardiac diseases.
Li X, Liu S, Qu L, Chen Y, Yuan C, Qin A, Liang J, Huang Q, Jiang M, Zou W. Li X, et al. J Ethnopharmacol. 2021 Jun 28;274:114018. doi: 10.1016/j.jep.2021.114018. Epub 2021 Mar 11. J Ethnopharmacol. 2021. PMID: 33716083 Review.
BACKGROUND AND ETHNOPHARMACOLOGICAL RELEVANCE: Dioscin and diosgenin derived from plants of the genus Dioscoreaceae such as D. nipponica and D. panthaica Prain et Burk. ...But the bioavailability of dioscin and diosgenin may be too low as a result of poor absorption …
BACKGROUND AND ETHNOPHARMACOLOGICAL RELEVANCE: Dioscin and diosgenin derived from plants of the genus Dioscoreaceae such as D. nippon …
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases.
Parama D, Boruah M, Yachna K, Rana V, Banik K, Harsha C, Thakur KK, Dutta U, Arya A, Mao X, Ahn KS, Kunnumakkara AB. Parama D, et al. Life Sci. 2020 Nov 1;260:118182. doi: 10.1016/j.lfs.2020.118182. Epub 2020 Aug 8. Life Sci. 2020. PMID: 32781063 Review.
AIM: To evaluate the literature available on the potential of diosgenin and its analogs in modulating different molecular targets leading to the prevention and treatment of chronic diseases. METHOD: A detailed literature search has been carried out on PubMed for gathering …
AIM: To evaluate the literature available on the potential of diosgenin and its analogs in modulating different molecular targets lea …
1,924 results