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Year Number of Results
1982 2
1983 1
1989 1
1992 1
1993 3
1994 1
1995 1
1996 2
1997 2
1999 6
2000 2
2001 3
2002 1
2003 4
2004 4
2005 2
2006 2
2007 2
2008 1
2010 3
2011 4
2012 7
2013 2
2014 1
2015 1
2016 1
2017 2
2018 3
2020 0
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20 results
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Filters applied: Meta-Analysis, Randomized Controlled Trial, Systematic Reviews, Adult: 19+ years. Clear all
Page 1
Comparison of dopamine and norepinephrine in the treatment of shock.
De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. De Backer D, et al. N Engl J Med. 2010 Mar 4;362(9):779-89. doi: 10.1056/NEJMoa0907118. N Engl J Med. 2010. PMID: 20200382 Free article. Clinical Trial.
BACKGROUND: Both dopamine and norepinephrine are recommended as first-line vasopressor agents in the treatment of shock. There is a continuing controversy about whether one agent is superior to the other. ...A subgroup analysis showed that dopamine, as compared with norepinephrine, was associated with an increased rate of death at 28 days among the 280 patients with cardiogenic shock but not among the 1044 patients with septic shock or the 263 with hypovolemic shock (P=0.03 for cardiogenic shock, P=0.19 for septic shock, and P=0.84 for hypovolemic shock, in Kaplan-Meier analyses). ...
BACKGROUND: Both dopamine and norepinephrine are recommended as first-line vasopressor agents in the treatment of shock. There …
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.
Schumann J, Henrich EC, Strobl H, Prondzinsky R, Weiche S, Thiele H, Werdan K, Frantz S, Unverzagt S. Schumann J, et al. Cochrane Database Syst Rev. 2018 Jan 29;1(1):CD009669. doi: 10.1002/14651858.CD009669.pub3. Cochrane Database Syst Rev. 2018. PMID: 29376560 Free PMC article. Review.
SELECTION CRITERIA: Randomised controlled trials in people with myocardial infarction, heart failure or cardiac surgery complicated by cardiogenic shock or LCOS. ...These comparisons investigated the efficacy of levosimendan versus dobutamine, enoximone or placebo, epinephrine versus norepinephrine-dobutamine, amrinone versus dobutamine, dopexamine versus dopamine, enoximone versus dopamine and nitric oxide versus placebo.All trials were published in peer-reviewed journals, and analysis was done by the intention-to-treat (ITT) principle. ...
SELECTION CRITERIA: Randomised controlled trials in people with myocardial infarction, heart failure or cardiac surgery complicated by cardi …
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.
Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, Douglas IS, Malhotra A, Owens RL, Feinstein DJ, Khan B, Pisani MA, Hyzy RC, Schmidt GA, Schweickert WD, Hite RD, Bowton DL, Masica AL, Thompson JL, Chandrasekhar R, Pun BT, Strength C, Boehm LM, Jackson JC, Pandharipande PP, Brummel NE, Hughes CG, Patel MB, Stollings JL, Bernard GR, Dittus RS, Ely EW; MIND-USA Investigators. Girard TD, et al. N Engl J Med. 2018 Dec 27;379(26):2506-2516. doi: 10.1056/NEJMoa1808217. Epub 2018 Oct 22. N Engl J Med. 2018. PMID: 30346242 Free PMC article. Clinical Trial.
METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. ...CONCLUSIONS: The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium. ...
METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hy …
Norepinephrine or dopamine for septic shock: systematic review of randomized clinical trials.
Vasu TS, Cavallazzi R, Hirani A, Kaplan G, Leiby B, Marik PE. Vasu TS, et al. J Intensive Care Med. 2012 May-Jun;27(3):172-8. doi: 10.1177/0885066610396312. Epub 2011 Mar 24. J Intensive Care Med. 2012. PMID: 21436167 Review.
BACKGROUND: There is debate as to the vasopressor agent of choice in patients with septic shock. According to current guidelines either dopamine or norepinephrine may be considered as the first-line agent for the management of refractory hypotension of septic shock. OBJECTIVE: The aim of this systematic review was to evaluate randomized clinical trials which compared norepinephrine versus dopamine in critically ill patients with septic shock or in a population of critically ill patients with shock predominantly secondary to sepsis. ...
BACKGROUND: There is debate as to the vasopressor agent of choice in patients with septic shock. According to current guidelines eith …
Prevention of acute kidney injury and protection of renal function in the intensive care unit: update 2017 : Expert opinion of the Working Group on Prevention, AKI section, European Society of Intensive Care Medicine.
Joannidis M, Druml W, Forni LG, Groeneveld ABJ, Honore PM, Hoste E, Ostermann M, Oudemans-van Straaten HM, Schetz M. Joannidis M, et al. Intensive Care Med. 2017 Jun;43(6):730-749. doi: 10.1007/s00134-017-4832-y. Epub 2017 Jun 2. Intensive Care Med. 2017. PMID: 28577069 Free PMC article. Review.
The following clinical conditions were considered: major surgery, critical illness, sepsis, shock, exposure to potentially nephrotoxic drugs and radiocontrast. ...The few strong recommendations with high-level evidence are mostly against the intervention in question (starches, low-dose dopamine, statins in cardiac surgery). ...
The following clinical conditions were considered: major surgery, critical illness, sepsis, shock, exposure to potentially nephrotoxi …
Comparison of norepinephrine-dobutamine to epinephrine for hemodynamics, lactate metabolism, and organ function variables in cardiogenic shock. A prospective, randomized pilot study.
Levy B, Perez P, Perny J, Thivilier C, Gerard A. Levy B, et al. Crit Care Med. 2011 Mar;39(3):450-5. doi: 10.1097/CCM.0b013e3181ffe0eb. Crit Care Med. 2011. PMID: 21037469 Clinical Trial.
Hence, the present study was designed to compare epinephrine and norepinephrine-dobutamine in dopamine-resistant cardiogenic shock. ...PATIENTS: Thirty patients with a cardiac index of <2.2 L/min/m and a mean arterial pressure of <60 mm Hg resistant to combined dopamine-dobutamine treatment and signs of shock. ...
Hence, the present study was designed to compare epinephrine and norepinephrine-dobutamine in dopamine-resistant cardiogenic shock
Efficacy and safety of dopamine versus norepinephrine in the management of septic shock.
Patel GP, Grahe JS, Sperry M, Singla S, Elpern E, Lateef O, Balk RA. Patel GP, et al. Shock. 2010 Apr;33(4):375-80. doi: 10.1097/SHK.0b013e3181c6ba6f. Shock. 2010. PMID: 19851126 Clinical Trial.
The optimum septic shock vasopressor support strategy is currently debated. This study was performed to evaluate the efficacy and safety of norepinephrine (NE) and dopamine (DA) as the initial vasopressor in septic shock patients who were managed with a specific treatment protocol. ...In this protocol-directed vasopressor support strategy for septic shock, DA and NE were equally effective as initial agents as judged by 28-day mortality rates. ...
The optimum septic shock vasopressor support strategy is currently debated. This study was performed to evaluate the efficacy and saf …
Dopamine versus norepinephrine in the treatment of shock.
Nathan Coxford R, Lang E, Dowling S. Nathan Coxford R, et al. CJEM. 2011 Nov;13(6):395-7. doi: 10.2310/8000.2011.110297. CJEM. 2011. PMID: 22436478 Clinical Trial.
CLINICAL QUESTION: Which vasopressor agent, norepinephrine or dopamine, is superior in the treatment of shock? ARTICLE CHOSEN: De Backer D, Biston P, Devriendt J, et al. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010;362:779-89. STUDY OBJECTIVE: The authors of this study set out to compare 28-day mortality in patients with shock who were treated with either dopamine or norepinephrine as initial vasopressor therapy. ...
CLINICAL QUESTION: Which vasopressor agent, norepinephrine or dopamine, is superior in the treatment of shock? ARTICLE CHOSEN: …
Testing a conceptual model on early opening of the microcirculation in severe sepsis and septic shock: a randomised controlled pilot study.
van der Voort PH, van Zanten M, Bosman RJ, van Stijn I, Wester JP, van Raalte R, Oudemans-van Straaten HM, Zandstra DF. van der Voort PH, et al. Eur J Anaesthesiol. 2015 Mar;32(3):189-98. doi: 10.1097/EJA.0000000000000126. Eur J Anaesthesiol. 2015. PMID: 25032942 Clinical Trial.
PATIENTS: Ninety severe sepsis and septic shock patients randomised to early opening microcirculation resuscitation group or standard resuscitation group. ...CONCLUSION: Early opening of the microcirculation in patients with severe sepsis and septic shock using nitroglycerin, enoximone, dopamine and corticosteroids did not result in a faster reduction in organ failure than standard resuscitation. ...
PATIENTS: Ninety severe sepsis and septic shock patients randomised to early opening microcirculation resuscitation group or standard …
The effects of levosimendan vs dobutamine added to dopamine on liver functions assessed with noninvasive liver function monitoring in patients with septic shock.
Memiş D, Inal MT, Sut N. Memiş D, et al. J Crit Care. 2012 Jun;27(3):318.e1-6. doi: 10.1016/j.jcrc.2011.06.008. Epub 2011 Aug 19. J Crit Care. 2012. PMID: 21855289 Clinical Trial.
OBJECTIVE: The aim of this study was to assess the effects of levosimendan vs dobutamine added to dopamine on liver functions assessed using noninvasive liver function monitoring (LiMON) in patients with septic shock. ...CONCLUSION: These results suggest that levosimendan added to dopamine improves systemic hemodynamics and increases splanchnic perfusion assessed using the user-friendly noninvasive bedside system LiMON in patients with septic shock compared with dobutamine....
OBJECTIVE: The aim of this study was to assess the effects of levosimendan vs dobutamine added to dopamine on liver functions assesse …
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