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Year Number of Results
1964 1
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1978 31
1979 28
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1981 35
1982 34
1983 38
1984 40
1985 35
1986 25
1987 25
1988 21
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1990 35
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1992 29
1993 35
1994 46
1995 48
1996 34
1997 38
1998 35
1999 79
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2001 214
2002 184
2003 209
2004 218
2005 209
2006 216
2007 220
2008 214
2009 199
2010 178
2011 164
2012 172
2013 179
2014 150
2015 136
2016 130
2017 114
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2022 96
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4,527 results

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Page 1
Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia.
Peirs C, Dallel R, Todd AJ. Peirs C, et al. J Neural Transm (Vienna). 2020 Apr;127(4):505-525. doi: 10.1007/s00702-020-02159-1. Epub 2020 Apr 2. J Neural Transm (Vienna). 2020. PMID: 32239353 Free PMC article. Review.
The dorsal horns of the spinal cord and the trigeminal nuclei in the brainstem contain neuron populations that are critical to process sensory information. ...There is a growing consensus concerning the classification of neuron populations, based on transcrip …
The dorsal horns of the spinal cord and the trigeminal nuclei in the brainstem contain neuron populations that are critical to …
Sensory neuron-derived Na(V)1.7 contributes to dorsal horn neuron excitability.
Alles SRA, Nascimento F, Luján R, Luiz AP, Millet Q, Bangash MA, Santana-Varela S, Zhou X, Cox JJ, Okorokov AL, Beato M, Zhao J, Wood JN. Alles SRA, et al. Sci Adv. 2020 Feb 19;6(8):eaax4568. doi: 10.1126/sciadv.aax4568. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128393 Free PMC article.
We examined the role of Na(V)1.7 in the dorsal horn of the spinal cord using an epitope-tagged Na(V)1.7 knock-in mouse. Immuno-electron microscopy showed the presence of Na(V)1.7 in dendrites of superficial dorsal horn neurons, despite the absence of m …
We examined the role of Na(V)1.7 in the dorsal horn of the spinal cord using an epitope-tagged Na(V)1.7 knock-in mouse. Immuno …
Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate.
Sykes MJ, Kekesi OS, Wong YT, Zhao FY, Spanswick D, Imlach WL. Sykes MJ, et al. Neuropharmacology. 2021 Oct 15;198:108755. doi: 10.1016/j.neuropharm.2021.108755. Epub 2021 Aug 17. Neuropharmacology. 2021. PMID: 34416268 Free article.
Excitatory and inhibitory neurotransmission within the spinal dorsal horn is tightly controlled to regulate transmission of nociceptive signals to the brain. ...Whole-cell voltage-clamp recordings from lamina II dorsal horn neurons of adult rats showed …
Excitatory and inhibitory neurotransmission within the spinal dorsal horn is tightly controlled to regulate transmission of no …
Lateral lamina V projection neuron axon collaterals connect sensory processing across the dorsal horn of the mouse spinal cord.
Browne TJ, Smith KM, Gradwell MA, Dayas CV, Callister RJ, Hughes DI, Graham BA. Browne TJ, et al. Sci Rep. 2024 Nov 1;14(1):26354. doi: 10.1038/s41598-024-73620-4. Sci Rep. 2024. PMID: 39487174 Free PMC article.
Here we use a retrograde viral transduction strategy to characterise a novel subpopulation of deep dorsal horn spinoparabrachial neurons. Brainbow assisted analysis confirmed that virally labelled PN cell bodies formed a discrete cell column in the lateral part of L …
Here we use a retrograde viral transduction strategy to characterise a novel subpopulation of deep dorsal horn spinoparabrachi …
Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition.
Arokiaraj CM, Leone MJ, Kleyman M, Chamessian A, Noh MC, Phan BN, Lopes BC, Corrigan KA, Cherupally VK, Yeramosu D, Franusich ME, Podder R, Lele S, Shiers S, Kang B, Kennedy MM, Chen V, Chen Z, Mathys H, Dum RP, Lewis DA, Qadri Y, Price TJ, Pfenning AR, Seal RP. Arokiaraj CM, et al. Cell Rep. 2024 Nov 26;43(11):114876. doi: 10.1016/j.celrep.2024.114876. Epub 2024 Oct 24. Cell Rep. 2024. PMID: 39453813 Free PMC article.
Key mechanisms underlying chronic pain occur within the dorsal horn. Genome-wide association studies (GWASs) have identified genetic variants predisposed to chronic pain. ...Here, we take a multi-species approach to determine whether chronic pain variants impact the …
Key mechanisms underlying chronic pain occur within the dorsal horn. Genome-wide association studies (GWASs) have identified g …
Hypoxia-induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain.
Da Vitoria Lobo ME, Weir N, Hardowar L, Al Ojaimi Y, Madden R, Gibson A, Bestall SM, Hirashima M, Schaffer CB, Donaldson LF, Bates DO, Hulse RP. Da Vitoria Lobo ME, et al. Pain. 2022 Nov 1;163(11):2264-2279. doi: 10.1097/j.pain.0000000000002627. Epub 2022 Mar 29. Pain. 2022. PMID: 35353768 Free PMC article.
Neuropathic pain, such as that seen in diabetes mellitus, results in part from central sensitisation in the dorsal horn. However, the mechanisms responsible for such sensitisation remain unclear. ...Here we show that reduced blood flow and vascularity of the dors …
Neuropathic pain, such as that seen in diabetes mellitus, results in part from central sensitisation in the dorsal horn. Howev …
Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord.
Harrington AM, Caraballo SG, Maddern JE, Grundy L, Castro J, Brierley SM. Harrington AM, et al. Am J Physiol Gastrointest Liver Physiol. 2019 Sep 1;317(3):G285-G303. doi: 10.1152/ajpgi.00013.2019. Epub 2019 Jun 12. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31188624 Free article.
In contrast, lumbosacral projections were identified from both lumen and wall tracing, present within various dorsal horn laminae, collateral tracts, and the dorsal gray commissure. Nonnoxious in vivo colorectal distension evoked significant neuronal activati …
In contrast, lumbosacral projections were identified from both lumen and wall tracing, present within various dorsal horn lami …
Deep Tissue Incision Enhances Spinal Dorsal Horn Neuron Activity During Static Isometric Muscle Contraction in Rats.
Gu H, Sugiyama D, Kang S, Brennan TJ. Gu H, et al. J Pain. 2019 Mar;20(3):301-314. doi: 10.1016/j.jpain.2018.09.012. Epub 2018 Oct 6. J Pain. 2019. PMID: 30296612 Free PMC article.
In vivo neuronal activity was recorded in 203 dorsal horn neurons (DHNs) from 97 rats after sham, skin-only, or skin + deep muscle incision. ...
In vivo neuronal activity was recorded in 203 dorsal horn neurons (DHNs) from 97 rats after sham, skin-only, or skin + deep mu …
Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity, and nociception.
Szabo NE, da Silva RV, Sotocinal SG, Zeilhofer HU, Mogil JS, Kania A. Szabo NE, et al. J Neurosci. 2015 Apr 1;35(13):5233-46. doi: 10.1523/JNEUROSCI.4690-14.2015. J Neurosci. 2015. PMID: 25834049 Free PMC article.
Specifically, we show that Lmx1b, previously shown to be expressed in glutamatergic dorsal horn neurons and critical for dorsal horn development, is expressed in nociceptive dorsal horn neurons and that its deletion results in the specifi …
Specifically, we show that Lmx1b, previously shown to be expressed in glutamatergic dorsal horn neurons and critical for do …
Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons.
Das Gupta RR, Scheurer L, Pelczar P, Wildner H, Zeilhofer HU. Das Gupta RR, et al. Sci Rep. 2021 Mar 4;11(1):5232. doi: 10.1038/s41598-021-84667-y. Sci Rep. 2021. PMID: 33664406 Free PMC article.
The spinal dorsal horn harbors a sophisticated and heterogeneous network of excitatory and inhibitory neurons that process peripheral signals encoding different sensory modalities. ...Subsequent multiplex in situ hybridization revealed eleven neuropeptide genes that …
The spinal dorsal horn harbors a sophisticated and heterogeneous network of excitatory and inhibitory neurons that process per …
4,527 results