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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1982 1
1997 1
1999 1
2001 1
2002 1
2003 1
2005 1
2007 1
2010 1
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2020 1
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16 results

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Page 1
The effects of antidepressants on cardiometabolic and other physiological parameters: a systematic review and network meta-analysis.
Pillinger T, Arumuham A, McCutcheon RA, D'Ambrosio E, Basdanis G, Branco M, Carr R, Finelli V, Furukawa TA, Gee S, Heald A, Jauhar S, Ma Z, Mancini V, Moulton C, Salanti G, Taylor DM, Tomlinson A, Young AH, Efthimiou O, Howes OD, Cipriani A. Pillinger T, et al. Lancet. 2025 Nov 1;406(10515):2063-2077. doi: 10.1016/S0140-6736(25)01293-0. Epub 2025 Oct 21. Lancet. 2025. PMID: 41135546 Free article.
We did frequentist random-effects network meta-analyses to investigate treatment-induced changes in weight; total cholesterol; glucose; heart rate; systolic and diastolic blood pressure; corrected QT interval (QTc); sodium; potassium; aspartate transferase (AST); alanine t …
We did frequentist random-effects network meta-analyses to investigate treatment-induced changes in weight; total cholesterol; glucose; hear …
Effect of lipid emulsion on neuropsychiatric drug-induced toxicity: A narrative review.
Hwang Y, Sohn JT. Hwang Y, et al. Medicine (Baltimore). 2024 Mar 15;103(11):e37612. doi: 10.1097/MD.0000000000037612. Medicine (Baltimore). 2024. PMID: 38489675 Free PMC article. Review.
The goal of this study was to examine the effect of lipid emulsions on neuropsychiatric drug-induced toxicity using relevant case reports of human patients, with a particular focus on the Glasgow Coma Scale (GCS) score and corrected QT interval, to analyze drugs that frequ …
The goal of this study was to examine the effect of lipid emulsions on neuropsychiatric drug-induced toxicity using relevant case reports of …
QT alterations in psychopharmacology: proven candidates and suspects.
Alvarez PA, Pahissa J. Alvarez PA, et al. Curr Drug Saf. 2010 Jan;5(1):97-104. doi: 10.2174/157488610789869265. Curr Drug Saf. 2010. PMID: 20210726 Review.
Psychotropics are among the most common causes of drug induced acquired long QT syndrome. Blockage of Human ether-a-go-go-related gene (HERG) potassium channel by psychoactive drugs appears to be related to this adverse effect. Antipsychotics such as haloperidol, thioridaz …
Psychotropics are among the most common causes of drug induced acquired long QT syndrome. Blockage of Human ether-a-go-go-related gen …
Psychotropic drugs and the ECG: focus on the QTc interval.
Goodnick PJ, Jerry J, Parra F. Goodnick PJ, et al. Expert Opin Pharmacother. 2002 May;3(5):479-98. doi: 10.1517/14656566.3.5.479. Expert Opin Pharmacother. 2002. PMID: 11996627 Review.
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the development of torsades de pointes and sudden death, particularly in patients predisposed to these complications due to cardiovascular impairme …
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the developmen …
A placebo- and active-controlled assessment of 6- and 50-mg oral doxepin on cardiac repolarization in healthy volunteers: a thorough QT evaluation.
Mansbach RS, Ludington E, Rogowski R, Kittrelle JP, Jochelson P. Mansbach RS, et al. Clin Ther. 2011 Jul;33(7):851-62. doi: 10.1016/j.clinthera.2011.05.092. Epub 2011 Jul 1. Clin Ther. 2011. PMID: 21722958 Clinical Trial.
OBJECTIVE: Because no previous thorough QT evaluation of doxepin has been conducted, the primary objective of this study was to assess the highest recommended dose (6 mg) and a supratherapeutic amount (50 mg) of doxepin on cardiac repolarization under steady- …
OBJECTIVE: Because no previous thorough QT evaluation of doxepin has been conducted, the primary objective of this study was t …
QT interval prolongation and torsades de pointes in a patient undergoing treatment with vorinostat: a case report and review of the literature.
Lynch DR Jr, Washam JB, Newby LK. Lynch DR Jr, et al. Cardiol J. 2012;19(4):434-8. Cardiol J. 2012. PMID: 22825908 Free article. Review.
A retrospective review of 116 patients from phase I and II clinical trials who had a baseline and at least one subsequent ECG revealed that four patients had Grade 2 and one patient had Grade 3 QTc interval prolongation; however, a MEDLINE search found no reported cases of tor …
A retrospective review of 116 patients from phase I and II clinical trials who had a baseline and at least one subsequent ECG revealed that …
The effect of tricyclic antidepressant drugs on the heart.
Dumovic P, Burrows GD, Vohra J, Davies B, Scoggins BA. Dumovic P, et al. Arch Toxicol. 1976 Aug 18;35(4):255-62. doi: 10.1007/BF00570267. Arch Toxicol. 1976. PMID: 989296
Guinea-pigs infused with doxepin survived significantly longer than those infused with amitriptyline, imipramine or nortriptyline. No statistically significant difference was found between the tricyclic drugs with respect to onset of widening of the QRS complex, increased …
Guinea-pigs infused with doxepin survived significantly longer than those infused with amitriptyline, imipramine or nortriptyline. No …
Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder.
Baker B, Dorian P, Sandor P, Shapiro C, Schell C, Mitchell J, Irvine MJ. Baker B, et al. J Clin Psychopharmacol. 1997 Feb;17(1):15-21. doi: 10.1097/00004714-199702000-00004. J Clin Psychopharmacol. 1997. PMID: 9004052 Clinical Trial.
Forty patients with major depressive disorder (according to DSM-III-R criteria) were enrolled in a 6-week double-blind parallel group study of fluoxetine (N = 20) or doxepin (N = 20). Cardiac conduction (QRS duration) and repolarization (corrected QT interval, QTc), …
Forty patients with major depressive disorder (according to DSM-III-R criteria) were enrolled in a 6-week double-blind parallel group study …
Drug-specific risk of severe QT prolongation following acute drug overdose.
Campleman SL, Brent J, Pizon AF, Shulman J, Wax P, Manini AF; Toxicology Investigators’ Consortium (ToxIC). Campleman SL, et al. Clin Toxicol (Phila). 2020 Dec;58(12):1326-1334. doi: 10.1080/15563650.2020.1746330. Epub 2020 Apr 7. Clin Toxicol (Phila). 2020. PMID: 32252558 Free PMC article.
Background: Severe QT prolongation (SQTP) has been identified as a strong predictor of adverse cardiovascular events in acute drug overdose, but drug-specific causes of SQTP in the setting of acute drug overdose remain unclear. ...The primary outcome was SQTP, which was de …
Background: Severe QT prolongation (SQTP) has been identified as a strong predictor of adverse cardiovascular events in acute drug ov …
16 results