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Year Number of Results
1978 1
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2010 8
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136 results

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Page 1
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P. Weibel S, et al. Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. Cochrane Database Syst Rev. 2020. PMID: 33075160 Free PMC article.
The certainty of evidence for SAEs when using one of the best and most reliable anti-vomiting drugs (aprepitant, ramosetron, granisetron, dexamethasone, ondansetron, and droperidol compared to placebo) ranged from very low to low. Droperidol (RR 0.88, 95% CI 0.08 to …
The certainty of evidence for SAEs when using one of the best and most reliable anti-vomiting drugs (aprepitant, ramosetron, granisetron, de …
Agitated Psychiatric Patient.
Pabst BM, Leung C, Frey JA, Yee J. Pabst BM, et al. J Educ Teach Emerg Med. 2020 Oct 15;5(4):S59-S83. doi: 10.21980/J85352. eCollection 2020 Oct. J Educ Teach Emerg Med. 2020. PMID: 37465334 Free PMC article.
Chemical and/or physical restraints are sometimes necessary to ensure patient and staff safety when verbal de-escalation is ineffective, particularly since agitation is the leading cause of hospital staff injuries.2 Chemical restraints have been shown to be less physically trauma …
Chemical and/or physical restraints are sometimes necessary to ensure patient and staff safety when verbal de-escalation is ineffective, par …
Droperidol, QT prolongation, and sudden death: what is the evidence?
Kao LW, Kirk MA, Evers SJ, Rosenfeld SH. Kao LW, et al. Ann Emerg Med. 2003 Apr;41(4):546-58. doi: 10.1067/mem.2003.110. Ann Emerg Med. 2003. PMID: 12658255 Review.
Its labeling has recently been revised, with a black box warning for cases of QT prolongation leading to torsades de pointes and death. A black box warning is applied when serious adverse drug reactions are uncovered for medications. We sought to examine the evidenc …
Its labeling has recently been revised, with a black box warning for cases of QT prolongation leading to torsades de pointes a …
Emergency medicine updates: Droperidol.
Cisewski D, Long B, Gottlieb M. Cisewski D, et al. Am J Emerg Med. 2022 Mar;53:180-184. doi: 10.1016/j.ajem.2022.01.011. Epub 2022 Jan 14. Am J Emerg Med. 2022. PMID: 35063889
OBJECTIVE: This paper provides evidence-based updates concerning the use of droperidol for the emergency clinician. DISCUSSION: Droperidol received a black box warning by the US FDA in 2001 due to concerns for QT prolongation and torsades de pointes; h …
OBJECTIVE: This paper provides evidence-based updates concerning the use of droperidol for the emergency clinician. DISCUSSION: Dr …
High dose droperidol and QT prolongation: analysis of continuous 12-lead recordings.
Calver L, Isbister GK. Calver L, et al. Br J Clin Pharmacol. 2014 May;77(5):880-6. doi: 10.1111/bcp.12272. Br J Clin Pharmacol. 2014. PMID: 24168079 Free PMC article.
AIMS: To investigate the QT interval after high dose droperidol using continuous 12-lead Holter recordings. METHODS: This was a prospective study of patients given droperidol with a continuous Holter recording. ...No patient given >30 mg had a prolonged …
AIMS: To investigate the QT interval after high dose droperidol using continuous 12-lead Holter recordings. METHODS: This was …
Reintegrating droperidol into emergency medicine practice.
Mattson A, Friend K, Brown CS, Cabrera D. Mattson A, et al. Am J Health Syst Pharm. 2020 Oct 30;77(22):1838-1845. doi: 10.1093/ajhp/zxaa271. Am J Health Syst Pharm. 2020. PMID: 32839811 Review.
SUMMARY: In 2001 the US Food and Drug Administration (FDA) mandated a boxed warning in the labeling of droperidol after reports of QT interval prolongation associated with droperidol use. Since that time, it has been difficult to access droperidol in t …
SUMMARY: In 2001 the US Food and Drug Administration (FDA) mandated a boxed warning in the labeling of droperidol after reports of …
Droperidol and ondansetron-induced QT interval prolongation: a clinical drug interaction study.
Charbit B, Alvarez JC, Dasque E, Abe E, Démolis JL, Funck-Brentano C. Charbit B, et al. Anesthesiology. 2008 Aug;109(2):206-12. doi: 10.1097/ALN.0b013e31817fd8c8. Anesthesiology. 2008. PMID: 18648229 Clinical Trial.
BACKGROUND: Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative nausea and vomiting. ...The objective was to study the effects of droperidol and ondansetron alone or in combination on QT in …
BACKGROUND: Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative …
Droperidol for Agitation in Acute Care.
Edge R, Argáez C. Edge R, et al. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jan. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jan. PMID: 34185452 Free Books & Documents. Review.
In 2001, a black box warning was issued by the US FDA for the use of droperidol based on post-marketing surveillance data.(,) The black box warning emphasized careful patient selection and increased monitoring to prevent corrected QT (QTc) interval elongation in pat …
In 2001, a black box warning was issued by the US FDA for the use of droperidol based on post-marketing surveillance data.(,) The bla …
The Incidence of QT Prolongation and Torsades des Pointes in Patients Receiving Droperidol in an Urban Emergency Department.
Cole JB, Lee SC, Martel ML, Smith SW, Biros MH, Miner JR. Cole JB, et al. West J Emerg Med. 2020 Jul 2;21(4):728-736. doi: 10.5811/westjem.2020.4.47036. West J Emerg Med. 2020. PMID: 32726229 Free PMC article.
INTRODUCTION: Droperidol carries a boxed warning from the United States Food and Drug Administration for QT prolongation and torsades des pointes (TdP). ...Thus, the objective of this study was to report the incidence of QT prolongation or TdP in patie …
INTRODUCTION: Droperidol carries a boxed warning from the United States Food and Drug Administration for QT prolongation and …
Vestibular neuritis.
Orr EJ. Orr EJ. N Engl J Med. 2003 Jun 5;348(23):2362-3; author reply 2362-3. doi: 10.1056/NEJMc030861. N Engl J Med. 2003. PMID: 12789006 No abstract available.
136 results