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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1991 1
1993 1
1994 2
1995 1
1997 1
1998 1
1999 1
2000 4
2001 2
2002 6
2003 13
2004 6
2005 7
2006 8
2007 6
2008 9
2009 5
2010 8
2011 2
2012 4
2013 7
2014 6
2015 6
2016 2
2018 2
2019 3
2020 10
2021 7
2022 4
2023 1

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130 results

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Page 1
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P. Weibel S, et al. Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. Cochrane Database Syst Rev. 2020. PMID: 33075160 Free PMC article.
The certainty of evidence for SAEs when using one of the best and most reliable anti-vomiting drugs (aprepitant, ramosetron, granisetron, dexamethasone, ondansetron, and droperidol compared to placebo) ranged from very low to low. Droperidol (RR 0.88, 95% CI 0.08 to …
The certainty of evidence for SAEs when using one of the best and most reliable anti-vomiting drugs (aprepitant, ramosetron, granisetron, de …
Safety and efficacy of pharmacologic agents used for rapid tranquilization of emergency department patients with acute agitation or excited delirium.
Kim HK, Leonard JB, Corwell BN, Connors NJ. Kim HK, et al. Expert Opin Drug Saf. 2021 Feb;20(2):123-138. doi: 10.1080/14740338.2021.1865911. Epub 2021 Jan 13. Expert Opin Drug Saf. 2021. PMID: 33327811 Review.
But there are differences in the time to sedation depending on which agent is used. Based upon the available studies, droperidol (5-10 mg IM) and midazolam (5-10 mg IM) have the fastest onset of sedation when either is used as a single agent. When combination therapy is us …
But there are differences in the time to sedation depending on which agent is used. Based upon the available studies, droperidol (5-1 …
Droperidol, QT prolongation, and sudden death: what is the evidence?
Kao LW, Kirk MA, Evers SJ, Rosenfeld SH. Kao LW, et al. Ann Emerg Med. 2003 Apr;41(4):546-58. doi: 10.1067/mem.2003.110. Ann Emerg Med. 2003. PMID: 12658255 Review.
Its labeling has recently been revised, with a black box warning for cases of QT prolongation leading to torsades de pointes and death. A black box warning is applied when serious adverse drug reactions are uncovered for medications. We sought to examine the evidenc …
Its labeling has recently been revised, with a black box warning for cases of QT prolongation leading to torsades de pointes a …
High dose droperidol and QT prolongation: analysis of continuous 12-lead recordings.
Calver L, Isbister GK. Calver L, et al. Br J Clin Pharmacol. 2014 May;77(5):880-6. doi: 10.1111/bcp.12272. Br J Clin Pharmacol. 2014. PMID: 24168079 Free PMC article.
AIMS: To investigate the QT interval after high dose droperidol using continuous 12-lead Holter recordings. ...No patient given >30 mg had a prolonged QT. There were no arrhythmias. CONCLUSION: QT prolongation was observed with high dose droperid …
AIMS: To investigate the QT interval after high dose droperidol using continuous 12-lead Holter recordings. ...No patient give …
Droperidol and ondansetron-induced QT interval prolongation: a clinical drug interaction study.
Charbit B, Alvarez JC, Dasque E, Abe E, Démolis JL, Funck-Brentano C. Charbit B, et al. Anesthesiology. 2008 Aug;109(2):206-12. doi: 10.1097/ALN.0b013e31817fd8c8. Anesthesiology. 2008. PMID: 18648229 Free article. Clinical Trial.
BACKGROUND: Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative nausea and vomiting. However, this adverse effect has never been confirmed and compared with both drugs under controlled conditions. The ob …
BACKGROUND: Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative …
The Incidence of QT Prolongation and Torsades des Pointes in Patients Receiving Droperidol in an Urban Emergency Department.
Cole JB, Lee SC, Martel ML, Smith SW, Biros MH, Miner JR. Cole JB, et al. West J Emerg Med. 2020 Jul 2;21(4):728-736. doi: 10.5811/westjem.2020.4.47036. West J Emerg Med. 2020. PMID: 32726229 Free PMC article.
INTRODUCTION: Droperidol carries a boxed warning from the United States Food and Drug Administration for QT prolongation and torsades des pointes (TdP). ...Thus, the objective of this study was to report the incidence of QT prolongation or TdP in patie …
INTRODUCTION: Droperidol carries a boxed warning from the United States Food and Drug Administration for QT prolongation and …
Evidence-based review and appraisal of the use of droperidol in the emergency department.
Lai PC, Huang YT. Lai PC, et al. Ci Ji Yi Xue Za Zhi. 2018 Jan-Mar;30(1):1-4. doi: 10.4103/tcmj.tcmj_195_17. Ci Ji Yi Xue Za Zhi. 2018. PMID: 29643708 Free PMC article. Review.
A black box warning was issued for droperidol by the United States Food and Drug Administration in 2001 because of a risk of development of torsades de pointes induced by QT prolongation. ...For these conditions, droperidol may be an option for shared …
A black box warning was issued for droperidol by the United States Food and Drug Administration in 2001 because of a risk of developm …
Reintegrating droperidol into emergency medicine practice.
Mattson A, Friend K, Brown CS, Cabrera D. Mattson A, et al. Am J Health Syst Pharm. 2020 Oct 30;77(22):1838-1845. doi: 10.1093/ajhp/zxaa271. Am J Health Syst Pharm. 2020. PMID: 32839811 Review.
SUMMARY: In 2001 the US Food and Drug Administration (FDA) mandated a boxed warning in the labeling of droperidol after reports of QT interval prolongation associated with droperidol use. ...Healthcare professionals can adopt droperidol for use in clin …
SUMMARY: In 2001 the US Food and Drug Administration (FDA) mandated a boxed warning in the labeling of droperidol after reports of …
Emergency medicine updates: Droperidol.
Cisewski D, Long B, Gottlieb M. Cisewski D, et al. Am J Emerg Med. 2022 Mar;53:180-184. doi: 10.1016/j.ajem.2022.01.011. Epub 2022 Jan 14. Am J Emerg Med. 2022. PMID: 35063889
OBJECTIVE: This paper provides evidence-based updates concerning the use of droperidol for the emergency clinician. DISCUSSION: Droperidol received a black box warning by the US FDA in 2001 due to concerns for QT prolongation and torsades de pointes; h …
OBJECTIVE: This paper provides evidence-based updates concerning the use of droperidol for the emergency clinician. DISCUSSION: Dr …
Droperidol for Agitation in Acute Care [Internet].
Edge R, Argáez C. Edge R, et al. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jan. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jan. PMID: 34185452 Free Books & Documents. Review.
In 2001, a black box warning was issued by the US FDA for the use of droperidol based on post-marketing surveillance data.(,) The black box warning emphasized careful patient selection and increased monitoring to prevent corrected QT (QTc) interval elongation in pat …
In 2001, a black box warning was issued by the US FDA for the use of droperidol based on post-marketing surveillance data.(,) The bla …
130 results