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Year Number of Results
2001 1
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25 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
Ikeotuonye AC, Umeora OJ, Nwafor JI, Ojumah BO, Ekwunife IC, Dimejesi IB. Ikeotuonye AC, et al. Afr Health Sci. 2022 Sep;22(3):108-116. doi: 10.4314/ahs.v22i3.13. Afr Health Sci. 2022. PMID: 36910347 Free PMC article. Clinical Trial.
RESULTS: The mean duration of active phase of labour (hour) was significantly lower in the drotaverine group compared to the control (drotaverine; 6.22 2.41 vs placebo; 8.33 3.56; p <0.001). Also, the cervical dilatation rate (cm/hr) was significantly faster …
RESULTS: The mean duration of active phase of labour (hour) was significantly lower in the drotaverine group compared to the control …
Drotaverine to improve progression of labor among nulliparous women.
Ibrahim MI, Alzeeniny HA, Ellaithy MI, Salama AH, Abdellatif MA. Ibrahim MI, et al. Int J Gynaecol Obstet. 2014 Feb;124(2):112-7. doi: 10.1016/j.ijgo.2013.08.013. Epub 2013 Nov 7. Int J Gynaecol Obstet. 2014. PMID: 24299975 Clinical Trial.
OBJECTIVE: To reevaluate the role of the antispasmodic drug drotaverine in shortening the length of the active first stage of labor among nulliparous women. ...Kaplan-Meier survival analysis showed a greater probability of faster delivery among patients treated by drota …
OBJECTIVE: To reevaluate the role of the antispasmodic drug drotaverine in shortening the length of the active first stage of labor a …
Drotaverine hydrochloride for augmentation of labor.
Singh KC, Jain P, Goel N, Saxena A. Singh KC, et al. Int J Gynaecol Obstet. 2004 Jan;84(1):17-22. doi: 10.1016/s0020-7292(03)00276-5. Int J Gynaecol Obstet. 2004. PMID: 14698825 Clinical Trial.
OBJECTIVES: To study the use of drotaverine hydrochloride for acceleration of labor and relief of labor pains. METHODS: In this double-blind placebo-controlled randomized study, 100 primigravidas in uncomplicated spontaneous labor at term were given drotaverine hydr …
OBJECTIVES: To study the use of drotaverine hydrochloride for acceleration of labor and relief of labor pains. METHODS: In this doubl …
Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor.
Sharma JB, Pundir P, Kumar A, Murthy NS. Sharma JB, et al. Int J Gynaecol Obstet. 2001 Sep;74(3):255-60. doi: 10.1016/s0020-7292(01)00448-9. Int J Gynaecol Obstet. 2001. PMID: 11543749 Clinical Trial.
The rate of cervical dilation was highest in the drotaverine group (2.04 cm/h) compared with the valethamate bromide group (1.86 cm/h) and control group (1.01 cm/h). There were no major maternal or fetal adverse effects in any group, but minor side effects were more common …
The rate of cervical dilation was highest in the drotaverine group (2.04 cm/h) compared with the valethamate bromide group (1.86 cm/h …
Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety.
Dash A, Maiti R, Akantappa Bandakkanavar TK, Arora P. Dash A, et al. Pain Med. 2012 Mar;13(3):466-71. doi: 10.1111/j.1526-4637.2011.01314.x. Epub 2012 Feb 1. Pain Med. 2012. PMID: 22295884 Clinical Trial.

RESULT: VAS decreased significantly (P < 0.001) with both drotaverine (52.4%) and diclofenac (49%) at 30 minutes. Reduction of VAS at 60 minutes was 61.3% with drotaverine in comparison to 60.4% with diclofenac. Forty-five patients (90%) in the drotaverine

…

RESULT: VAS decreased significantly (P < 0.001) with both drotaverine (52.4%) and diclofenac (49%) at 30 minutes. Reduction of VAS

…
Drotaverine hydrochloride versus hyoscine-N-butylbromide in augmentation of labor.
Gupta B, Nellore V, Mittal S. Gupta B, et al. Int J Gynaecol Obstet. 2008 Mar;100(3):244-7. doi: 10.1016/j.ijgo.2007.08.020. Epub 2007 Nov 26. Int J Gynaecol Obstet. 2008. PMID: 18031745 Clinical Trial.
OBJECTIVES: To study and compare the efficacy and side effects of drotaverine hydrochloride and hyoscine-N-butylbromide in the augmentation of labor. METHODS: A prospective randomized trial of 150 women in active labor included 50 women given drotaverine (group 1), …
OBJECTIVES: To study and compare the efficacy and side effects of drotaverine hydrochloride and hyoscine-N-butylbromide in the augmen …
Efficacy and safety of drotaverine hydrochloride in irritable bowel syndrome: a randomized double-blind placebo-controlled study.
Rai RR, Dwivedi M, Kumar N. Rai RR, et al. Saudi J Gastroenterol. 2014 Nov-Dec;20(6):378-82. doi: 10.4103/1319-3767.145331. Saudi J Gastroenterol. 2014. PMID: 25434320 Free PMC article. Clinical Trial.

Pain severity scores also decreased significantly in the drotaverine group 66 (77.7%) as compared with placebo 26 (30.6%) after 4 weeks. Drotaverine HCl was shown to provide significant improvement (P < 0.01) in global relief in abdominal pain as perceived by the

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Pain severity scores also decreased significantly in the drotaverine group 66 (77.7%) as compared with placebo 26 (30.6%) after 4 wee …
Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial.
Narang M, Shah D, Akhtar H. Narang M, et al. Indian Pediatr. 2015 Oct;52(10):847-51. doi: 10.1007/s13312-015-0730-y. Indian Pediatr. 2015. PMID: 26499007 Free article. Clinical Trial.
INTERVENTION: Children between 4-6 years of age received 10 mL syrup orally (20 mg drotaverine hydrochloride or placebo) thrice daily for 4 weeks while children >6 years of age received one tablet orally (40 mg drotaverine hydrochloride or placebo) thrice daily f …
INTERVENTION: Children between 4-6 years of age received 10 mL syrup orally (20 mg drotaverine hydrochloride or placebo) thrice daily …
The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones.
Romics I, Molnár DL, Timberg G, Mrklic B, Jelakovic B, Köszegi G, Blaskó G. Romics I, et al. BJU Int. 2003 Jul;92(1):92-6. doi: 10.1046/j.1464-410x.2003.04262.x. BJU Int. 2003. PMID: 12823389 Clinical Trial.
The primary endpoint was the evaluation of the antispasmodic effect of drotaverine during a 3-h study period, to confirm that drotaverine abolished or significantly decreased the intensity of pain in renal colic. ...RESULTS: Drotaverine was effective in 79% o …
The primary endpoint was the evaluation of the antispasmodic effect of drotaverine during a 3-h study period, to confirm that drot …
Bioavailability study of drotaverine from capsule and tablet preparations in healthy volunteers.
Dyderski S, Grześkowiak E, Drobnik L, Szałek E, Balcerkiewicz M, Dubai V. Dyderski S, et al. Arzneimittelforschung. 2004;54(5):298-302. doi: 10.1055/s-0031-1296974. Arzneimittelforschung. 2004. PMID: 15212193 Clinical Trial.
The bioavailability of drotaverine (CAS 14009-24-6) was investigated after oral administration of a drotaverine capsule preparation (20 mg Droxa mite) and compared to that of a reference tablet preparation. ...A washout period of two weeks separated both treatment p …
The bioavailability of drotaverine (CAS 14009-24-6) was investigated after oral administration of a drotaverine capsule prepar …
25 results