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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 6
1947 12
1948 16
1949 12
1950 19
1951 22
1952 34
1953 38
1954 32
1955 42
1956 40
1957 49
1958 44
1959 51
1960 46
1961 56
1962 55
1963 46
1964 46
1965 20
1966 1
1968 2
1970 1
1972 1
1975 10
1976 23
1977 21
1978 26
1979 32
1980 23
1981 37
1982 42
1983 57
1984 61
1985 67
1986 67
1987 64
1988 54
1989 63
1990 82
1991 67
1992 76
1993 82
1994 59
1995 75
1996 68
1997 75
1998 83
1999 69
2000 61
2001 69
2002 63
2003 56
2004 78
2005 80
2006 70
2007 64
2008 70
2009 65
2010 82
2011 99
2012 79
2013 107
2014 181
2015 218
2016 258
2017 285
2018 340
2019 295
2020 345
2021 261
2022 122
2023 116
2024 132
2025 141
2026 96

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5,373 results

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Page 1
Drugs in pregnancy: Pharmacologic and physiologic changes that affect clinical care.
Pinheiro EA, Stika CS. Pinheiro EA, et al. Semin Perinatol. 2020 Apr;44(3):151221. doi: 10.1016/j.semperi.2020.151221. Epub 2020 Jan 25. Semin Perinatol. 2020. PMID: 32115202 Free PMC article. Review.
With the recognition of pregnancy as a special pharmacokinetic population in the late 1990s, investigators have begun to study drug disposition in this unique patient dyad. Many of the basic physiologic changes that occur during pregnancy have significant impact on drug …
With the recognition of pregnancy as a special pharmacokinetic population in the late 1990s, investigators have begun to study drug d …
Pharmacogenomics in pregnancy.
Betcher HK, George AL Jr. Betcher HK, et al. Semin Perinatol. 2020 Apr;44(3):151222. doi: 10.1016/j.semperi.2020.151222. Epub 2020 Jan 25. Semin Perinatol. 2020. PMID: 32081407 Free PMC article. Review.
Research on pharmacogenomic and pharmacokinetic influences on drug disposition during pregnancy has lagged behind other fields. Clinical investigators have demonstrated altered activity of several drug metabolizing enzymes during pregnancy. ...Pharmacogenomics also …
Research on pharmacogenomic and pharmacokinetic influences on drug disposition during pregnancy has lagged behind other fields. Clini …
Predicting when biliary excretion of parent drug is a major route of elimination in humans.
Hosey CM, Broccatelli F, Benet LZ. Hosey CM, et al. AAPS J. 2014 Sep;16(5):1085-96. doi: 10.1208/s12248-014-9636-1. Epub 2014 Jul 9. AAPS J. 2014. PMID: 25004821 Free PMC article.
Biliary excretion is an important route of elimination for many drugs, yet measuring the extent of biliary elimination is difficult, invasive, and variable. ...An accurate prediction of which drugs or new molecular entities are significantly eliminated in the …
Biliary excretion is an important route of elimination for many drugs, yet measuring the extent of biliary elimination …
Pharmacokinetic studies in pregnancy.
Avram MJ. Avram MJ. Semin Perinatol. 2020 Apr;44(3):151227. doi: 10.1016/j.semperi.2020.151227. Epub 2020 Jan 27. Semin Perinatol. 2020. PMID: 32093881 Free PMC article. Review.
The dose-response relationship is affected by pharmacokinetics, or what the body does to a drug, and pharmacodynamics, or what a drug does to the body. Insights into the potential effects of the changes of pregnancy on one aspect of the dose-response relationship of …
The dose-response relationship is affected by pharmacokinetics, or what the body does to a drug, and pharmacodynamics, or what a d …
Elimination Pathways of Nanoparticles.
Poon W, Zhang YN, Ouyang B, Kingston BR, Wu JLY, Wilhelm S, Chan WCW. Poon W, et al. ACS Nano. 2019 May 28;13(5):5785-5798. doi: 10.1021/acsnano.9b01383. Epub 2019 Apr 26. ACS Nano. 2019. PMID: 30990673
A proposed pathway for these nanoparticles is hepatobiliary elimination, but their transport has not been well-studied. Here, we explored the barriers that determined the elimination of nanoparticles through the hepatobiliary route. The route of hepato …
A proposed pathway for these nanoparticles is hepatobiliary elimination, but their transport has not been well-studied. Here, we expl …
Dapagliflozin modulates plasma lipidomic profile and urinary metabolite excretion in type 2 diabetes.
Pezzica S, Pratesi F, Sabatini S, Carli F, Mengozzi A, Solini A, Gastaldelli A. Pezzica S, et al. Cardiovasc Diabetol. 2025 Dec 30;25(1):31. doi: 10.1186/s12933-025-03018-7. Cardiovasc Diabetol. 2025. PMID: 41469882 Free PMC article. Clinical Trial.
CLINICAL TRIAL INFORMATION: European Union Drug Regulating Authorities Clinical Trials No. 2015-004164-11....
CLINICAL TRIAL INFORMATION: European Union Drug Regulating Authorities Clinical Trials No. 2015-004164-11....
Increased Intestinal Permeability Is Associated With Later Development of Crohn's Disease.
Turpin W, Lee SH, Raygoza Garay JA, Madsen KL, Meddings JB, Bedrani L, Power N, Espin-Garcia O, Xu W, Smith MI, Griffiths AM, Moayyedi P, Turner D, Seidman EG, Steinhart AH, Marshall JK, Jacobson K, Mack D, Huynh H, Bernstein CN, Paterson AD; Crohn’s and Colitis Canada Genetic Environmental Microbial Project Research Consortium; CCC GEM Project recruitment site directors include Maria Abreu; Croitoru K. Turpin W, et al. Gastroenterology. 2020 Dec;159(6):2092-2100.e5. doi: 10.1053/j.gastro.2020.08.005. Epub 2020 Aug 10. Gastroenterology. 2020. PMID: 32791132
5,373 results