Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 3
1947 5
1948 4
1949 3
1950 4
1951 6
1952 6
1953 4
1954 5
1955 1
1956 3
1957 5
1958 1
1959 3
1961 2
1962 4
1963 8
1964 9
1965 5
1966 12
1967 21
1968 25
1969 26
1970 30
1971 29
1972 30
1973 42
1974 58
1975 150
1976 163
1977 188
1978 180
1979 220
1980 190
1981 212
1982 215
1983 269
1984 333
1985 328
1986 350
1987 350
1988 360
1989 425
1990 428
1991 500
1992 571
1993 524
1994 504
1995 573
1996 592
1997 586
1998 572
1999 604
2000 644
2001 701
2002 783
2003 845
2004 823
2005 985
2006 1046
2007 1092
2008 1078
2009 1317
2010 1426
2011 1464
2012 1690
2013 1935
2014 1999
2015 2140
2016 2278
2017 2276
2018 2241
2019 2142
2020 2091
2021 1893
2022 1461
2023 1430
2024 1989
2025 2384
2026 1717
2027 13

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

46,083 results

Results by year

Filters applied: . Clear all
Page 1
Implant dynamics, inner structure, and their impact on drug release of in situ forming implants uncovered through CT imaging.
Lin X, Al Zouabi NN, Ward LE, Zhen Z, Darji M, Masese FK, Hargrove D, O'Reilly Beringhs A, Kasi RM, Li Q, Zhang Q, Qin B, Wang Y, Jay M, Yuan H, Lu X. Lin X, et al. J Control Release. 2024 Nov;375:802-811. doi: 10.1016/j.jconrel.2024.09.045. Epub 2024 Oct 4. J Control Release. 2024. PMID: 39349184
The implant inner structure identified through SEM, implant size change, and polymer degradation along with the CT real time imaging all consistently support the implant formation differences and their implant on the drug release. Similar patter …
The implant inner structure identified through SEM, implant size change, and polymer degradation along with the CT real time i …
Laser-Activated Drug Implant for Controlled Release to the Posterior Segment of the Eye.
He X, Yuan Z, Gaeke S, Kao WW, Li SK, Miller D, Williams B, Park YC. He X, et al. ACS Appl Bio Mater. 2021 Feb 15;4(2):1461-1469. doi: 10.1021/acsabm.0c01334. Epub 2021 Jan 22. ACS Appl Bio Mater. 2021. PMID: 35014495 Free PMC article.
To treat chronic posterior eye diseases, frequent intravitreal injections or sustained-release drug implants are the current standard of care. Sustained-release drug implants often involve burst release of the drugs and the dosage from the implants …
To treat chronic posterior eye diseases, frequent intravitreal injections or sustained-release drug implants are the current s …
Effect of implant formation on drug release kinetics of in situ forming implants.
Suh MS, Kastellorizios M, Tipnis N, Zou Y, Wang Y, Choi S, Burgess DJ. Suh MS, et al. Int J Pharm. 2021 Jan 5;592:120105. doi: 10.1016/j.ijpharm.2020.120105. Epub 2020 Nov 21. Int J Pharm. 2021. PMID: 33232755
In situ forming implants are attractive long-acting implant dosage forms due to their: i) ability to control drug release; ii) simple manufacturing process; and iii) minimally invasive administration. In situ forming implants are typically made of a …
In situ forming implants are attractive long-acting implant dosage forms due to their: i) ability to control drug relea …
Implant contraception.
Meckstroth KR, Darney PD. Meckstroth KR, et al. Semin Reprod Med. 2001 Dec;19(4):339-54. doi: 10.1055/s-2001-18642. Semin Reprod Med. 2001. PMID: 11727176 Review.
The experience of 6 million Norplant users has led to several more advanced implants. Implanon is a single-rod implant system containing a low androgenic progestin and requires 1 to 2 minutes for insertion and removal. ...Irregular bleeding is the most common advers …
The experience of 6 million Norplant users has led to several more advanced implants. Implanon is a single-rod implant system …
Difficult implant removals.
Voedisch A, Hugin M. Voedisch A, et al. Curr Opin Obstet Gynecol. 2017 Dec;29(6):449-457. doi: 10.1097/GCO.0000000000000416. Curr Opin Obstet Gynecol. 2017. PMID: 28938375 Review.
This review discusses the overall approach to potentially problematic removals and the appropriate steps to avoid complications and safely remove implants. RECENT FINDINGS: Given the rapid uptake of contraceptive implants and subsequent need for removals, an Impl …
This review discusses the overall approach to potentially problematic removals and the appropriate steps to avoid complications and safely r …
Orthopedic implant used as drug delivery system: clinical situation and state of the research.
Pioletti DP, Gauthier O, Stadelmann VA, Bujoli B, Guicheux J, Zambelli PY, Bouler JM. Pioletti DP, et al. Curr Drug Deliv. 2008 Jan;5(1):59-63. doi: 10.2174/156720108783331041. Curr Drug Deliv. 2008. PMID: 18220552 Review.
A partial review is proposed on the existing literature for the research performed in orthopedic implant used as drug delivery system. In the first part, an evaluation is given on the clinical need to deliver a drug in the surrounding of an implant. Se …
A partial review is proposed on the existing literature for the research performed in orthopedic implant used as drug delivery …
Intra-operatively customized implant coating strategies for local and controlled drug delivery to bone.
Trajkovski B, Petersen A, Strube P, Mehta M, Duda GN. Trajkovski B, et al. Adv Drug Deliv Rev. 2012 Sep;64(12):1142-51. doi: 10.1016/j.addr.2012.05.016. Epub 2012 Jun 1. Adv Drug Deliv Rev. 2012. PMID: 22664228 Review.
We describe currently available methods for local drug delivery and their limitations in therapy. Various solutions for drug delivery to bone focusing on clinical applications and intra-operative constraints are discussed and drug delivery by implant c …
We describe currently available methods for local drug delivery and their limitations in therapy. Various solutions for drug d …
An intravitreal implant injection method for sustained drug delivery into mouse eyes.
Sun YJ, Lin CH, Wu MR, Lee SH, Yang J, Kunchur CR, Mujica EM, Chiang B, Jung YS, Wang S, Mahajan VB. Sun YJ, et al. Cell Rep Methods. 2021 Dec 20;1(8):100125. doi: 10.1016/j.crmeth.2021.100125. Epub 2021 Dec 6. Cell Rep Methods. 2021. PMID: 35128514 Free PMC article.
Using small molecule drugs to treat eye diseases carries benefits of specificity, scalability, and transportability, but their efficacy is significantly limited by a fast intraocular clearance rate. Ocular drug implants (ODIs) present a compelling means for the slow …
Using small molecule drugs to treat eye diseases carries benefits of specificity, scalability, and transportability, but their efficacy is s …
A novel, minimally invasive implant to assist in repeated intraocular drug delivery.
Chawla R, Bhattacharyya J, Moksha L, Phour A, Velpandian T, Kashyap S, Kalyanasundaram D. Chawla R, et al. Biomed Microdevices. 2022 May 19;24(2):17. doi: 10.1007/s10544-022-00618-y. Biomed Microdevices. 2022. PMID: 35587289
Subsequent intravitreal injections were administered under topical anaesthesia with a 30-gauge needle through the implant thus delivering the drug into the vitreous cavity. Repeated intravitreal injections were administered every 2 weeks via the implant for 3 …
Subsequent intravitreal injections were administered under topical anaesthesia with a 30-gauge needle through the implant thus delive …
The contraceptive implant.
Hohmann H, Creinin MD. Hohmann H, et al. Clin Obstet Gynecol. 2007 Dec;50(4):907-17. doi: 10.1097/GRF.0b013e318159c2f6. Clin Obstet Gynecol. 2007. PMID: 17982333 Review.
Contraceptive implants provide long-acting, highly effective reversible contraception. Currently, the only subdermal implant available to women in the United States is the single rod etonogestrel implant, Implanon (N.V. Organon, Oss, the Netherlands) approved …
Contraceptive implants provide long-acting, highly effective reversible contraception. Currently, the only subdermal implant a …
46,083 results
You have reached the last available page of results. Please see the User Guide for more information.