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Page 1
Drug repositioning: a brief overview.
Jourdan JP, Bureau R, Rochais C, Dallemagne P. Jourdan JP, et al. J Pharm Pharmacol. 2020 Sep;72(9):1145-1151. doi: 10.1111/jphp.13273. Epub 2020 Apr 17. J Pharm Pharmacol. 2020. PMID: 32301512 Free PMC article. Review.
OBJECTIVES: Drug repositioning, that is, the use of a drug in an indication other than the one for which it was initially marketed, is a growing trend. ...Serendipity is not yet useful to find repositioning drugs. Drug repositioning is of …
OBJECTIVES: Drug repositioning, that is, the use of a drug in an indication other than the one for which it was initial …
[Drug repositioning].
Réda C, Villoutreix B, Delahaye-Duriez A. Réda C, et al. Rev Prat. 2024 Nov;74(9):942-946. Rev Prat. 2024. PMID: 39625015 French.
DRUG REPOSITIONING. Developing new therapeutic agents ("de novo") for human diseases is an increasingly lengthy and costly process, aimed at ensuring patient safety and drug efficacy. An alternative approach, drug repurposing or repositioning, i …
DRUG REPOSITIONING. Developing new therapeutic agents ("de novo") for human diseases is an increasingly lengthy and costly pro …
Drug Repositioning for Hand, Foot, and Mouth Disease.
Yan R, He J, Liu G, Zhong J, Xu J, Zheng K, Ren Z, He Z, Zhu Q. Yan R, et al. Viruses. 2022 Dec 27;15(1):75. doi: 10.3390/v15010075. Viruses. 2022. PMID: 36680115 Free PMC article. Review.
HFMD currently presents a major threat to infants and young children because of a lack of antiviral drugs in clinical practice. Drug repositioning is an attractive drug discovery strategy aimed at identifying and developing new drugs for diseases. ...In this …
HFMD currently presents a major threat to infants and young children because of a lack of antiviral drugs in clinical practice. Drug …
Drug repositioning trends in rare and intractable diseases.
Sakate R, Kimura T. Sakate R, et al. Drug Discov Today. 2022 Jul;27(7):1789-1795. doi: 10.1016/j.drudis.2022.01.013. Epub 2022 Jan 29. Drug Discov Today. 2022. PMID: 35104621 Free article. Review.
Drug repositioning (DR) is an effective way for developing drugs for rare and intractable diseases (RIDs). ...Here, we review the current situation of ontology in RIDs, the trends in drug development, and an efficient strategy for DR based on drug targ …
Drug repositioning (DR) is an effective way for developing drugs for rare and intractable diseases (RIDs). ...Here, we review …
Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection.
Kosić M, Pajović V, Jovanović M, Japundžić-Žigon N. Kosić M, et al. Int J Mol Sci. 2025 Oct 17;26(20):10130. doi: 10.3390/ijms262010130. Int J Mol Sci. 2025. PMID: 41155422 Free PMC article. Review.
Doxorubicin (DOX) is an effective drug for the treatment of solid tumors and hematological malignancies in both children and adults. ...The precise mechanisms underlying DIC are not fully understood, and currently, no fully effective preventive or therapeutic strategies ex …
Doxorubicin (DOX) is an effective drug for the treatment of solid tumors and hematological malignancies in both children and adults. …
Drug Repositioning Using Computer-aided Drug Design (CADD).
Rawat S, Subramaniam K, Subramanian SK, Subbarayan S, Dhanabalan S, Chidambaram SKM, Stalin B, Roy A, Nagaprasad N, Aruna M, Tesfaye JL, Badassa B, Krishnaraj R. Rawat S, et al. Curr Pharm Biotechnol. 2024;25(3):301-312. doi: 10.2174/1389201024666230821103601. Curr Pharm Biotechnol. 2024. PMID: 37605405 Review.
Drug repositioning is a method of using authorized drugs for other unusually complex diseases. ...The use of CADD's special strategy for target-based drug reuse is the most promising method, and its realization rate is high. In this review article, we have pa …
Drug repositioning is a method of using authorized drugs for other unusually complex diseases. ...The use of CADD's special st …
Drug repositioning for rare diseases: Knowledge-based success stories.
Scherman D, Fetro C. Scherman D, et al. Therapie. 2020 Apr;75(2):161-167. doi: 10.1016/j.therap.2020.02.007. Epub 2020 Feb 13. Therapie. 2020. PMID: 32164975 Review.
Drug repositioning (also called drug repurposing, drug reprofiling or drug re-tasking) consists in identifying for an already approved or investigational drug a new use outside the scope of the original medical indication. Drug …
Drug repositioning (also called drug repurposing, drug reprofiling or drug re-tasking) consists in identi …
Drug Repositioning for Ovarian Cancer Treatment: An Update.
Cavalluzzi MM, Viale M, Rotondo NP, Ferraro V, Lentini G. Cavalluzzi MM, et al. Anticancer Agents Med Chem. 2024;24(8):637-647. doi: 10.2174/0118715206282904240122063914. Anticancer Agents Med Chem. 2024. PMID: 38367265 Review.
Despite the advances in surgical and chemotherapeutic options, OC treatment is still a challenge, and new anticancer agents are urgently needed. Drug repositioning has gained significant attention in drug discovery, representing a smart way to identify new cl …
Despite the advances in surgical and chemotherapeutic options, OC treatment is still a challenge, and new anticancer agents are urgently nee …
Structure-based drug repositioning: Potential and limits.
Adasme MF, Parisi D, Sveshnikova A, Schroeder M. Adasme MF, et al. Semin Cancer Biol. 2021 Jan;68:192-198. doi: 10.1016/j.semcancer.2020.01.010. Epub 2020 Feb 4. Semin Cancer Biol. 2021. PMID: 32032699 Review.
Drug repositioning, the assignment of new therapeutic purposes to known drugs, is an established strategy with many repurposed drugs on the market and many more at experimental stage. ...Finally, we show that the availability of data on targets is an important limit …
Drug repositioning, the assignment of new therapeutic purposes to known drugs, is an established strategy with many repurposed …
Drug Repositioning for COVID-19.
Benavides-Cordoba V. Benavides-Cordoba V. Colomb Med (Cali). 2020 Jun 30;51(2):e4279. doi: 10.25100/cm.v51i2.4279. Colomb Med (Cali). 2020. PMID: 33012890 Free PMC article. Review.
Drug repositioning is a strategy that identifies new uses of approved drugs to treat conditions different from their original purpose. ...In this review, we present a selection of drugs, of different classes and with potential activity against COVID-19, whose trials …
Drug repositioning is a strategy that identifies new uses of approved drugs to treat conditions different from their original …
10,586 results
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