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4 results

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Filters applied: Randomized Controlled Trial, in the last 5 years, Humans, English. Clear all
Page 1
Pharmacokinetic and pharmacodynamic herb-drug interaction of aspirin with Ijintang (Er Chen Tang) or Cheongsanggyeontongtang (Qing Shang Juan Tong Tang): An exploratory study in healthy adults.
Hwang I, Kim JH, Song J, Kim H, Cho HY, Lee SW. Hwang I, et al. J Ethnopharmacol. 2026 Feb 10;356:120776. doi: 10.1016/j.jep.2025.120776. Epub 2025 Oct 22. J Ethnopharmacol. 2026. PMID: 41135614 Clinical Trial.
This concurrent use creates a high potential for clinically significant herb-drug interactions. AIM OF THE STUDY: This study aimed to evaluate the potential pharmacokinetic (PK) and pharmacodynamic (PD) interactions between aspirin and two herbal formu …
This concurrent use creates a high potential for clinically significant herb-drug interactions. AIM OF THE STUDY: This …
The Pharmacokinetic Interaction Between Metformin and the Natural Product Goldenseal Is Metformin Dose-Dependent: A Three-Arm Crossover Study in Adults With Type 2 Diabetes.
Nguyen JT, Arian CM, Tanna RS, Cherel MG, Layton ME, White JR, Thummel KE, Paine MF. Nguyen JT, et al. Clin Transl Sci. 2025 Feb;18(2):e70120. doi: 10.1111/cts.70120. Clin Transl Sci. 2025. PMID: 39943692 Free PMC article. Clinical Trial.
Pharmacokinetic drug interactions can lead to unexpected changes in plasma concentrations of the object drug, potentially increasing the risk for adverse effects and/or decreasing therapeutic efficacy. ...The disconnect between changes in metformin systemic e …
Pharmacokinetic drug interactions can lead to unexpected changes in plasma concentrations of the object drug, potential …
Impact of Banhabaekchulcheonmatang (Banxia Baizhu Tianma Tang) and Hwangryeonhaedoktang (Huang Lian Jie Du Tang) on edoxaban: Herb-drug interaction study in healthy subjects.
Cho SJ, Song J, Kang DW, Kim JH, Kim H, Chung H, Cho HY. Cho SJ, et al. J Ethnopharmacol. 2025 Jan 30;337(Pt 3):118997. doi: 10.1016/j.jep.2024.118997. Epub 2024 Oct 24. J Ethnopharmacol. 2025. PMID: 39461388 Clinical Trial.
ETHNOPHARMACOLOGICAL RELEVANCE: Concurrent use of traditional herbal medicines and conventional drugs, particularly for stroke treatment, is widespread, raising concerns about potential drug interactions. AIM OF THE STUDY: This clinical study aimed to investigate …
ETHNOPHARMACOLOGICAL RELEVANCE: Concurrent use of traditional herbal medicines and conventional drugs, particularly for stroke treatment, is …
The influence of green tea extract on nintedanib's bioavailability in patients with pulmonary fibrosis.
Veerman GDM, van der Werff SC, Koolen SLW, Miedema JR, Oomen-de Hoop E, van der Mark SC, Chandoesing PP, de Bruijn P, Wijsenbeek MS, Mathijssen RHJ. Veerman GDM, et al. Biomed Pharmacother. 2022 Jul;151:113101. doi: 10.1016/j.biopha.2022.113101. Epub 2022 May 17. Biomed Pharmacother. 2022. PMID: 35594703 Free article. Clinical Trial.
Nintedanib is an oral small-molecule kinase inhibitor and first-line treatment for idiopathic pulmonary fibrosis. Nintedanib is a substrate of the drug efflux transporter ABCB1. Green tea flavonoids --especially epigallocatechin gallate (EGCG)-- are potent ABCB1 modulators …
Nintedanib is an oral small-molecule kinase inhibitor and first-line treatment for idiopathic pulmonary fibrosis. Nintedanib is a substrate …