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Page 1
Fatigue-inducing stimulation resolves myotonia in a drug-induced model.
van Lunteren E, Spiegler SE, Moyer M. van Lunteren E, et al. BMC Physiol. 2011 Feb 28;11:5. doi: 10.1186/1472-6793-11-5. BMC Physiol. 2011. PMID: 21356096 Free PMC article.
Diaphragm, EDL, and soleus muscles were examined in vitro during repetitive 20 Hz and 50 Hz train stimulation in a drug-induced (9-AC) rat myotonia model. RESULTS: At the onset of stimulation, 9-AC treated diaphragm and EDL muscle had markedly prolonged half …
Diaphragm, EDL, and soleus muscles were examined in vitro during repetitive 20 Hz and 50 Hz train stimulation in a drug-induced …
Drug-induced myotonia in human intercostal muscle.
Kwieciński H, Lehmann-Horn F, Rüdel R. Kwieciński H, et al. Muscle Nerve. 1988 Jun;11(6):576-81. doi: 10.1002/mus.880110609. Muscle Nerve. 1988. PMID: 2455224
The myotonia-inducing effects of furosemide and clofibrate, two widely used pharmaceutical agents, were investigated in excised human external intercostal muscle. ...Short trains of direct stimuli were often followed by after-activity, and this caused a myotonia-lik …
The myotonia-inducing effects of furosemide and clofibrate, two widely used pharmaceutical agents, were investigated in excised human …
Drug-induced myopathies in man.
Lane RJ, Mastaglia FL. Lane RJ, et al. Lancet. 1978 Sep 9;2(8089):562-6. doi: 10.1016/s0140-6736(78)92894-5. Lancet. 1978. PMID: 79927
Drug-induced diseases constitute up to 5% of hospital admissions,a figure which almost certainly understates the total morbidity due to drugs1. Sever drug-induced myopathies are uncommon, but milder forms may be more prevalent than is generally appreci …
Drug-induced diseases constitute up to 5% of hospital admissions,a figure which almost certainly understates the total morbidi …
Treatment updates in myotonic disorders.
Matthews E, Specterman MJ, Mul K. Matthews E, et al. J Neurol. 2026 Sep 4;273(10):562. doi: 10.1007/s00415-026-14073-9. J Neurol. 2026. PMID: 42698007 Free PMC article. Review.
Myotonia is delayed muscle relaxation after forceful contraction. It is due to hyperexcitability of the skeletal muscle membrane. ...It is a symptom that almost always indicates a genetic diagnosis, although it can occur in acquired conditions, including metabolic and d …
Myotonia is delayed muscle relaxation after forceful contraction. It is due to hyperexcitability of the skeletal muscle membrane. ... …
Adverse effects of drugs on muscle.
Mastaglia FL. Mastaglia FL. Drugs. 1982 Oct;24(4):304-21. doi: 10.2165/00003495-198224040-00003. Drugs. 1982. PMID: 6128217 Review.
The precise incidence of such disorders is not known, but it is almost certainly higher than is generally suspected. An important aspect of drug-induced muscular disorders is their reversibility if the offending agent is withdrawn, whereas failure to do so may lead …
The precise incidence of such disorders is not known, but it is almost certainly higher than is generally suspected. An important aspect of …
Levodopa-induced dyskinesia: interplay between the N-methyl-D-aspartic acid receptor and neuroinflammation.
Zhang F, Liu M, Tuo J, Zhang L, Zhang J, Yu C, Xu Z. Zhang F, et al. Front Immunol. 2023 Oct 4;14:1253273. doi: 10.3389/fimmu.2023.1253273. eCollection 2023. Front Immunol. 2023. PMID: 37860013 Free PMC article. Review.
Parkinson's disease (PD) is a common neurodegenerative disorder of middle-aged and elderly people, clinically characterized by resting tremor, myotonia, reduced movement, and impaired postural balance. Clinically, patients with PD are often administered levodopa (L-DOPA) t …
Parkinson's disease (PD) is a common neurodegenerative disorder of middle-aged and elderly people, clinically characterized by resting tremo …
Increase of muscle peroxisomal enzymes and myotonia induced by nafenopin, a hypolipidemic drug.
Behrens MI, Soza MA, Inestrosa NC. Behrens MI, et al. Muscle Nerve. 1983 Feb;6(2):154-9. doi: 10.1002/mus.880060212. Muscle Nerve. 1983. PMID: 6855799
The chronic administration of nafenopin, a hypolipidemic drug, induced an increase in catalase and acyl-CoA oxidase activities in various skeletal muscles, including the gracilis, diaphragm, soleus, and extensor digitorum longus. ...Concomitant with the increase in …
The chronic administration of nafenopin, a hypolipidemic drug, induced an increase in catalase and acyl-CoA oxidase activities …
[Malignant hyperthermia. The ugly].
Rüffert H, Wehner M, Deutrich C, Olthoff D. Rüffert H, et al. Anaesthesist. 2007 Sep;56(9):923-9. doi: 10.1007/s00101-007-1218-5. Anaesthesist. 2007. PMID: 17565473 Review. German.
Furthermore, it may also be generated by other mechanisms which disturb the membranous integrity of skeletal muscle cells (e.g. some myotonias, muscular dystrophies, malformation syndromes). Hyperthermia is only one of a number of life-threatening symptoms that may occur d …
Furthermore, it may also be generated by other mechanisms which disturb the membranous integrity of skeletal muscle cells (e.g. some myot …
16 results