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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1972 2
1973 1
1974 3
1975 9
1976 9
1977 8
1978 6
1979 7
1980 10
1981 12
1982 4
1983 9
1984 11
1985 10
1986 11
1987 6
1988 14
1989 10
1990 22
1991 27
1992 20
1993 37
1994 39
1995 33
1996 52
1997 52
1998 58
1999 88
2000 85
2001 111
2002 120
2003 140
2004 186
2005 201
2006 236
2007 324
2008 308
2009 304
2010 364
2011 473
2012 477
2013 560
2014 605
2015 529
2016 547
2017 613
2018 608
2019 563
2020 553
2021 485
2022 331
2023 320
2024 352
2025 438
2026 331

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8,990 results

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Page 1
Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On.
Everitt BJ, Robbins TW. Everitt BJ, et al. Annu Rev Psychol. 2016;67:23-50. doi: 10.1146/annurev-psych-122414-033457. Epub 2015 Aug 7. Annu Rev Psychol. 2016. PMID: 26253543 Review.
A decade ago, we hypothesized that drug addiction can be viewed as a transition from voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by a transition from prefrontal cortical to striatal control over drug …
A decade ago, we hypothesized that drug addiction can be viewed as a transition from voluntary, recreational drug use to compu …
The transition to compulsion in addiction.
Lüscher C, Robbins TW, Everitt BJ. Lüscher C, et al. Nat Rev Neurosci. 2020 May;21(5):247-263. doi: 10.1038/s41583-020-0289-z. Epub 2020 Mar 30. Nat Rev Neurosci. 2020. PMID: 32231315 Free PMC article. Review.
Compulsion is a cardinal symptom of drug addiction (severe substance use disorder). However, compulsion is observed in only a small proportion of individuals who repeatedly seek and use addictive substances. ...Importantly, we emphasize the conceptual distinctions between …
Compulsion is a cardinal symptom of drug addiction (severe substance use disorder). However, compulsion is observed in only a small p …
Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior.
Bobadilla AC, Heinsbroek JA, Gipson CD, Griffin WC, Fowler CD, Kenny PJ, Kalivas PW. Bobadilla AC, et al. Prog Brain Res. 2017;235:93-112. doi: 10.1016/bs.pbr.2017.07.013. Epub 2017 Oct 12. Prog Brain Res. 2017. PMID: 29054293 Free PMC article. Review.
The idea that interconnected neuronal ensembles code for specific behaviors has been around for decades; however, recent technical improvements allow studying these networks and their causal role in initiating and maintaining behavior. In particular, the role of ensembles …
The idea that interconnected neuronal ensembles code for specific behaviors has been around for decades; however, recent technical improveme …
An extended history of drug self-administration results in multiple sources of control over drug seeking behavior.
Clemens KJ, Holmes NM. Clemens KJ, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Dec 20;87(Pt A):48-55. doi: 10.1016/j.pnpbp.2017.11.011. Epub 2017 Nov 10. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29129722 Review.
This paper reviews the literature on drug self-administration in animals to address these gaps. It first identifies the different types of cues that acquire control over reward seeking behavior generally, and examines whether the same types of cues acquire co …
This paper reviews the literature on drug self-administration in animals to address these gaps. It first identifies the different typ …
Evaluation of drug seeking behavior on nicotine conditioned place preference in zebrafish.
Rocco L, Pisera-Fuster A, Faillace MP, Bernabeu R. Rocco L, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2022 Dec 20;119:110593. doi: 10.1016/j.pnpbp.2022.110593. Epub 2022 Jun 28. Prog Neuropsychopharmacol Biol Psychiatry. 2022. PMID: 35777525
Seeking of drugs is commonly evaluated in a specific environment for assessing drug preference. However, cognitive strategies involved in drug seeking are mostly unknown. To assess the strength of environmental cues that can be associated with nicotine …
Seeking of drugs is commonly evaluated in a specific environment for assessing drug preference. However, cognitive strategies …
Modular Maximization Theory: A functional account of economic behavior in laboratory animal models with applications to drug-seeking behavior.
Sanabria F, Gildea M, Gutiérrez B, Santos C, Hibshman A. Sanabria F, et al. Neurosci Biobehav Rev. 2025 Feb;169:106010. doi: 10.1016/j.neubiorev.2025.106010. Epub 2025 Jan 13. Neurosci Biobehav Rev. 2025. PMID: 39814118 Review.
To address these gaps, the Modular Maximization Theory (MMT) is introduced as a comprehensive framework for understanding instrumental behavior. Like earlier maximization theories, MMT posits that behavior is distributed across alternatives to maximize utility over …
To address these gaps, the Modular Maximization Theory (MMT) is introduced as a comprehensive framework for understanding instrumental be …
Extinction of drug seeking.
Millan EZ, Marchant NJ, McNally GP. Millan EZ, et al. Behav Brain Res. 2011 Mar 1;217(2):454-62. doi: 10.1016/j.bbr.2010.10.037. Epub 2010 Nov 10. Behav Brain Res. 2011. PMID: 21073904 Review.
Drug seeking behavior can be reduced or inhibited via extinction. The brain mechanisms for extinction of drug seeking are poorly understood but are of significant interest because of their potential to identify novel approaches that promote abst …
Drug seeking behavior can be reduced or inhibited via extinction. The brain mechanisms for extinction of drug …
Social rank modulates methamphetamine-seeking in dominant and subordinate male rodents via distinct dopaminergic pathways.
Deng X, Xu W, Liu Y, Jing H, Zhong J, Sun K, Zhou R, Xu L, Wu X, Zhang B, Chen W, Jiang S, Chen G, Zhu Y. Deng X, et al. Nat Neurosci. 2025 Jun;28(6):1268-1279. doi: 10.1038/s41593-025-01951-0. Epub 2025 May 12. Nat Neurosci. 2025. PMID: 40355612
Social status has a profound impact on mental health and propensity towards drug addiction. However, the neural mechanisms underlying the effects of social rank on drug-seeking behavior remain unclear. ...These results provide a framework for understan …
Social status has a profound impact on mental health and propensity towards drug addiction. However, the neural mechanisms underlying …
Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats.
Cho BR, Gerena J, Olekanma DI, Bal A, Herrera Charpentier AN, Arguello AA. Cho BR, et al. Psychopharmacology (Berl). 2020 Sep;237(9):2823-2833. doi: 10.1007/s00213-020-05575-z. Epub 2020 Jun 29. Psychopharmacology (Berl). 2020. PMID: 32601989 Free PMC article.
Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adolescent-formed, context-drug-associations to elicit relapse-like behavior is underexplored. Although it is known that social isolation can impact dr …
Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adolescent-formed, context- …
Dopamine and relapse to drug seeking.
Liu Y, McNally GP. Liu Y, et al. J Neurochem. 2021 Jun;157(5):1572-1584. doi: 10.1111/jnc.15309. Epub 2021 Feb 10. J Neurochem. 2021. PMID: 33486769 Review.
The actions of dopamine are essential to relapse to drug seeking but we still lack a precise understanding of how dopamine achieves these effects. Here we review recent advances from animal models in understanding how dopamine controls relapse to drug seek …
The actions of dopamine are essential to relapse to drug seeking but we still lack a precise understanding of how dopamine ach …
8,990 results