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BRD9 Is a Critical Regulator of Androgen Receptor Signaling and Prostate Cancer Progression.

Alpsoy A, Utturkar SM, Carter BC, Dhiman A, Torregrosa-Allen SE, Currie MP, Elzey BD, Dykhuizen EC. Alpsoy A, et al. Among authors: dykhuizen ec. Cancer Res. 2021 Feb 15;81(4):820-833. doi: 10.1158/0008-5472.CAN-20-1417. Epub 2020 Dec 21. Cancer Res. 2021. PMID: 33355184 Free PMC article.

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Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8*.

Milosevich N, Wilson CR, Brown TM, Alpsoy A, Wang S, Connelly KE, Sinclair KAD, Ponio FR, Hof R, Dykhuizen EC, Hof F. Milosevich N, et al. Among authors: dykhuizen ec. ChemMedChem. 2021 Oct 6;16(19):3027-3034. doi: 10.1002/cmdc.202100262. Epub 2021 Jul 23. ChemMedChem. 2021. PMID: 34174168

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A chemoproteomic portrait of the oncometabolite fumarate.

Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Among authors: dykhuizen ec. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.

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Compositional and functional diversity of canonical PRC1 complexes in mammals.

Connelly KE, Dykhuizen EC. Connelly KE, et al. Among authors: dykhuizen ec. Biochim Biophys Acta Gene Regul Mech. 2017 Feb;1860(2):233-245. doi: 10.1016/j.bbagrm.2016.12.006. Epub 2016 Dec 20. Biochim Biophys Acta Gene Regul Mech. 2017. PMID: 28007606 Review.

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Polycomb group proteins in cancer: multifaceted functions and strategies for modulation.

Wang S, C Ordonez-Rubiano S, Dhiman A, Jiao G, Strohmier BP, Krusemark CJ, Dykhuizen EC. Wang S, et al. Among authors: dykhuizen ec. NAR Cancer. 2021 Oct 4;3(4):zcab039. doi: 10.1093/narcan/zcab039. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34617019 Free PMC article.

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MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.

Wigton EJ, Mikami Y, McMonigle RJ, Castellanos CA, Wade-Vallance AK, Zhou SK, Kageyama R, Litterman A, Roy S, Kitamura D, Dykhuizen EC, Allen CDC, Hu H, O'Shea JJ, Ansel KM. Wigton EJ, et al. Among authors: dykhuizen ec. J Exp Med. 2021 Nov 1;218(11):e20201422. doi: 10.1084/jem.20201422. Epub 2021 Sep 29. J Exp Med. 2021. PMID: 34586363 Free PMC article.

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PBRM1 Regulates Stress Response in Epithelial Cells.

Porter EG, Dhiman A, Chowdhury B, Carter BC, Lin H, Stewart JC, Kazemian M, Wendt MK, Dykhuizen EC. Porter EG, et al. Among authors: dykhuizen ec. iScience. 2019 May 31;15:196-210. doi: 10.1016/j.isci.2019.04.027. Epub 2019 Apr 26. iScience. 2019. PMID: 31077944 Free PMC article.

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At the Crossroad of Gene Regulation and Genome Organization: Potential Roles for ATP-Dependent Chromatin Remodelers in the Regulation of CTCF-Mediated 3D Architecture.

Alpsoy A, Sood S, Dykhuizen EC. Alpsoy A, et al. Among authors: dykhuizen ec. Biology (Basel). 2021 Mar 27;10(4):272. doi: 10.3390/biology10040272. Biology (Basel). 2021. PMID: 33801596 Free PMC article. Review.

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A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation.

Wang S, Alpsoy A, Sood S, Ordonez-Rubiano SC, Dhiman A, Sun Y, Jiao G, Krusemark CJ, Dykhuizen EC. Wang S, et al. Among authors: dykhuizen ec. Chembiochem. 2021 Jul 1;22(13):2335-2344. doi: 10.1002/cbic.202100118. Epub 2021 May 28. Chembiochem. 2021. PMID: 33950564

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Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells.

Cai B, Kim D, Akhand S, Sun Y, Cassell RJ, Alpsoy A, Dykhuizen EC, Van Rijn RM, Wendt MK, Krusemark CJ. Cai B, et al. Among authors: dykhuizen ec. J Am Chem Soc. 2019 Oct 30;141(43):17057-17061. doi: 10.1021/jacs.9b08085. Epub 2019 Oct 22. J Am Chem Soc. 2019. PMID: 31613623 Free PMC article.

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