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12 results

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Page 1
Glucose-induced inhibition of insulin secretion.
Hellman B, Grapengiesser E. Hellman B, et al. Acta Physiol (Oxf). 2014 Mar;210(3):479-88. doi: 10.1111/apha.12217. Epub 2014 Jan 16. Acta Physiol (Oxf). 2014. PMID: 24354538 Review.
The introductory inhibition is characteristic of the healthy beta-cell and mediated by sequestration of [Ca(2+) ]i in the endoplasmic reticulum. This inhibition is easily seen in studies of isolated islets but too brief to be detected in a conventional intravenous glucose …
The introductory inhibition is characteristic of the healthy beta-cell and mediated by sequestration of [Ca(2+) ]i in the endoplasmic reticu …
Capacitance measurements in the mouse rod bipolar cell identify a pool of releasable synaptic vesicles.
Zhou ZY, Wan QF, Thakur P, Heidelberger R. Zhou ZY, et al. J Neurophysiol. 2006 Nov;96(5):2539-48. doi: 10.1152/jn.00688.2006. Epub 2006 Aug 16. J Neurophysiol. 2006. PMID: 16914610 Free article.
The amplitude of the capacitance response recorded from the easily accessible soma of an intact mouse rod bipolar cell was identical to that recorded directly from the small synaptic terminal, suggesting that in the carefully selected cohort of cells presented here, axonal …
The amplitude of the capacitance response recorded from the easily accessible soma of an intact mouse rod bipolar cell was identical …
[Presynaptic mechanisms of learning and memory].
Yawo H, Ishizuka T. Yawo H, et al. Brain Nerve. 2008 Jul;60(7):725-36. Brain Nerve. 2008. PMID: 18646612 Review. Japanese.
We found that there are 2 distinct vesicle pools: a resting pool, which is resistant to exocytosis, and a releasable pool. The initially docked vesicles are easily depleted and the readily releasable pool (RRP) is replenished by the reser …
We found that there are 2 distinct vesicle pools: a resting pool, which is resistant to exocytosis, and a releasable pool …
Synaptic vesicle dynamics in the mossy fiber-CA3 presynaptic terminals of mouse hippocampus.
Suyama S, Hikima T, Sakagami H, Ishizuka T, Yawo H. Suyama S, et al. Neurosci Res. 2007 Dec;59(4):481-90. doi: 10.1016/j.neures.2007.08.019. Epub 2007 Sep 12. Neurosci Res. 2007. PMID: 17933408
The presynaptic mechanisms underlying the fidelity of transmission were investigated for the MF-CA3 synapses. The relative size of readily releasable pool (RRP) of vesicles was estimated by counting the number of docked vesicles at an active zone (AZ) on the transmi …
The presynaptic mechanisms underlying the fidelity of transmission were investigated for the MF-CA3 synapses. The relative size of readily …
Compartmentalization of monoaminergic synaptic vesicles in the storage and release of neurotransmitter.
Pellegrino de Iraldi A. Pellegrino de Iraldi A. Mol Neurobiol. 1992 Winter;6(4):323-37. doi: 10.1007/BF02757939. Mol Neurobiol. 1992. PMID: 1363047 Review.
Thus, the matrix is a constant component of the vesicle, whereas the core is a transient one. Each compartment has a different pool of amine: a loosely bound, easily releasable pool in the matrix and a tightly bound, more resistant pool in the c …
Thus, the matrix is a constant component of the vesicle, whereas the core is a transient one. Each compartment has a different pool o …
[Short term synaptic plasticity].
Colino A, Muñoz J, Vara H. Colino A, et al. Rev Neurol. 2002 Mar 16-31;34(6):593-9. Rev Neurol. 2002. PMID: 12040507 Review. Spanish.
Thus, synapses with high release probability show few facilitation and are easily depressed because of their ability to deplete faster all synaptic vesicles of the ready releasable pool. ...
Thus, synapses with high release probability show few facilitation and are easily depressed because of their ability to deplete faste …
Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse.
Chang S, Reim K, Pedersen M, Neher E, Brose N, Taschenberger H. Chang S, et al. J Neurosci. 2015 May 27;35(21):8272-90. doi: 10.1523/JNEUROSCI.4841-14.2015. J Neurosci. 2015. PMID: 26019341 Free PMC article.
Studies involving genetic mutation, knock-down, or knock-out indicated two key functions of Cplx that are not mutually exclusive but cannot easily be reconciled, one in facilitating SV fusion, and one in "clamping" SVs to prevent premature fusion. ...Because action potenti …
Studies involving genetic mutation, knock-down, or knock-out indicated two key functions of Cplx that are not mutually exclusive but cannot …
Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates.
Cattaneo M, Canciani MT, Lecchi A, Kinlough-Rathbone RL, Packham MA, Mannucci PM, Mustard JF. Cattaneo M, et al. Blood. 1990 Mar 1;75(5):1081-6. Blood. 1990. PMID: 2137716 Free article.
In contrast, thrombin-induced aggregates of platelets from patients with delta-storage pool deficiency (delta-SPD), which lack releasable nucleotides, are readily deaggregated by the same combination of inhibitors. ...(whose platelets have a severe, selective impair …
In contrast, thrombin-induced aggregates of platelets from patients with delta-storage pool deficiency (delta-SPD), which lack rel …
Tetanus toxin and botulinum A toxin inhibit acetylcholine release from but not calcium uptake into brain tissue.
Bigalke H, Ahnert-Hilger G, Habermann E. Bigalke H, et al. Naunyn Schmiedebergs Arch Pharmacol. 1981 Apr;316(2):143-8. doi: 10.1007/BF00505308. Naunyn Schmiedebergs Arch Pharmacol. 1981. PMID: 7242701
Both toxins appear to impede the Ca2+-dependent mobilization of an easily releasable acetylcholine pool, without inhibiting the transmembranal calcium fluxes....
Both toxins appear to impede the Ca2+-dependent mobilization of an easily releasable acetylcholine pool, without inhibi …
Delay in granular fusion evoked by repetitive cytosolic Ca2+ spikes in mouse pancreatic acinar cells.
Maruyama Y, Petersen OH. Maruyama Y, et al. Cell Calcium. 1994 Nov;16(5):419-30. doi: 10.1016/0143-4160(94)90035-3. Cell Calcium. 1994. PMID: 7859255
This might be due to gradual washout of low molecular components responsible for exocytosis under the whole-cell recording condition. Second, the pool of immediately releasable or of primed zymogen granules is easily exhausted or desensitized during the Ca2+ …
This might be due to gradual washout of low molecular components responsible for exocytosis under the whole-cell recording condition. Second …
12 results