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1965 5
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1981 1
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2000 1
2002 1
2003 4
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2006 1
2007 1
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2018 6
2019 10
2020 2
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Proliferative and Inhibitory Activity of Siberian ginseng (Eleutherococcus senticosus) Extract on Cancer Cell Lines; A-549, XWLC-05, HCT-116, CNE and Beas-2b.
Cichello SA, Yao Q, Dowell A, Leury B, He XQ. Cichello SA, et al. Asian Pac J Cancer Prev. 2015;16(11):4781-6. doi: 10.7314/apjcp.2015.16.11.4781. Asian Pac J Cancer Prev. 2015. PMID: 26107240 Free article.
Siberian ginseng (Eleutherococcus senticosus) is used primarily as an adaptogen herb and also for its immune stimulant properties in Western herbal medicine. ...Further, in XWLC-05 (Yunnan lung cancer cell line), E. senticosus methanolic extract displa …
Siberian ginseng (Eleutherococcus senticosus) is used primarily as an adaptogen herb and also for its immune stimulant propert …
Caspase-3/MAPK pathways as main regulators of the apoptotic effect of the phyto-mediated synthesized silver nanoparticle from dried stem of Eleutherococcus senticosus in human cancer cells.
Kim CG, Castro-Aceituno V, Abbai R, Lee HA, Simu SY, Han Y, Hurh J, Kim YJ, Yang DC. Kim CG, et al. Biomed Pharmacother. 2018 Mar;99:128-133. doi: 10.1016/j.biopha.2018.01.050. Epub 2018 Jan 10. Biomed Pharmacother. 2018. PMID: 29331758
Siberian ginseng (Eleutherococcus senticosus) was used for the synthesis of an ecofriendly silver nanoparticle (Sg-AgNP), which has exhibited antibacterial, antioxidant effect and lower cytotoxicity to normal cells in comparison to human cancer cells. ...Resu …
Siberian ginseng (Eleutherococcus senticosus) was used for the synthesis of an ecofriendly silver nanoparticle (Sg-AgNP), whic …
Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look.
Davydov M, Krikorian AD. Davydov M, et al. J Ethnopharmacol. 2000 Oct;72(3):345-93. doi: 10.1016/s0378-8741(00)00181-1. J Ethnopharmacol. 2000. PMID: 10996277 Review.
We attempted to identify critically what an adaptogen supposedly does and to determine whether the word embodies in and of itself any concept(s) acceptable to western conventional (allopathic) medicine. Special attention was paid to the reported pharmacological effects of …
We attempted to identify critically what an adaptogen supposedly does and to determine whether the word embodies in and of itself any concep …
Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
Panossian A, Seo EJ, Efferth T. Panossian A, et al. Phytomedicine. 2018 Nov 15;50:257-284. doi: 10.1016/j.phymed.2018.09.204. Epub 2018 Sep 20. Phytomedicine. 2018. PMID: 30466987 Free article.
AIM OF THE STUDY: The aim of this study was to identify key molecular mechanisms of adaptogenic plants traditionally used to treat stress and aging-related disorders, i.e., Rhodiola rosea, Eleutherococcus senticosus, Withania somnifera, Rhaponticum carthamoides, and …
AIM OF THE STUDY: The aim of this study was to identify key molecular mechanisms of adaptogenic plants traditionally used to treat stress an …
Acanthopanax senticosus polysaccharide suppressing proliferation and metastasis of the human non-small cell lung cancer NCI-H520 cells is associated with Wnt/beta-catenin signaling.
Sun D, Chen J, Hu H, Lin S, Jin L, Luo L, Yan X, Zhang C. Sun D, et al. Neoplasma. 2019 Jul 23;66(4):555-563. doi: 10.4149/neo_2018_180913N689. Epub 2019 Mar 30. Neoplasma. 2019. PMID: 30943746
Lung cancer (LC) is the highest lethality in all tumors. Non-small cell lung cancer (NSCLC) accounts for about 80% of all LC. Acanthopanax senticosus polysaccharide (ASPS) is extracted from the root of Acanthopanax senticosus (AS). ...
Lung cancer (LC) is the highest lethality in all tumors. Non-small cell lung cancer (NSCLC) accounts for about 80% of all LC. …
Effects of anti-inflammatory and adaptogenic herbal extracts on gene expression of eicosanoids signaling pathways in isolated brain cells.
Panossian A, Seo EJ, Efferth T. Panossian A, et al. Phytomedicine. 2019 Jul;60:152881. doi: 10.1016/j.phymed.2019.152881. Epub 2019 Mar 10. Phytomedicine. 2019. PMID: 30987861 Free article.
RESULTS: For the first time, we demonstrated that Rhodiola rosea, Withania somnifera and Eleutherococcus senticosus downregulate the expression of key genes (ALOX5AP, DPEP2, LTC4S) involved biosynthesis of leukotrienes A, B, C, D and E, resulting in inhibition of le …
RESULTS: For the first time, we demonstrated that Rhodiola rosea, Withania somnifera and Eleutherococcus senticosus downregula …
A review of Acanthopanax senticosus (Rupr and Maxim.) harms: From ethnopharmacological use to modern application.
Jia A, Zhang Y, Gao H, Zhang Z, Zhang Y, Wang Z, Zhang J, Deng B, Qiu Z, Fu C. Jia A, et al. J Ethnopharmacol. 2021 Mar 25;268:113586. doi: 10.1016/j.jep.2020.113586. Epub 2020 Nov 16. J Ethnopharmacol. 2021. PMID: 33212178 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Acanthopanax senticosus (AS), previously classified as Eleutherococcus senticosus, is one of the most commonly used herbs in the Chinese materia medica. ...Representative pathways stimulated by AS are related to neuroactive lig …
ETHNOPHARMACOLOGICAL RELEVANCE: Acanthopanax senticosus (AS), previously classified as Eleutherococcus senticosus, is o …
Intraspecific relationship analysis by DNA markers and in vitro cytotoxic and antioxidant activity in Eleutherococcus senticosus.
Yu CY, Kim SH, Lim JD, Kim MJ, Chung IM. Yu CY, et al. Toxicol In Vitro. 2003 Apr;17(2):229-36. doi: 10.1016/s0887-2333(03)00008-0. Toxicol In Vitro. 2003. PMID: 12650677
To analyse genetic relationships and intraspecific variation within Eleutherococcus senticosus, the polymerase chain reaction (PCR) was performed on total genomic DNAs of 10 Eleutherococcus collections. ...Thus, RAPD analysis was useful in determining genetic …
To analyse genetic relationships and intraspecific variation within Eleutherococcus senticosus, the polymerase chain reaction …
Reactive oxygen species mediate the chemopreventive effects of syringin in breast cancer cells.
Lee CH, Huang CW, Chang PC, Shiau JP, Lin IP, Lin MY, Lai CC, Chen CY. Lee CH, et al. Phytomedicine. 2019 Aug;61:152844. doi: 10.1016/j.phymed.2019.152844. Epub 2019 Jan 28. Phytomedicine. 2019. PMID: 31029906
BACKGROUND: Syringin (Syr), a phenylpropanoid glycoside extracted from Eleutherococcus senticosus, possesses various biological properties, including anticancer activities. ...CONCLUSION: Our findings suggest that Syr induces oxidative stress to suppress the prolife …
BACKGROUND: Syringin (Syr), a phenylpropanoid glycoside extracted from Eleutherococcus senticosus, possesses various biologica …
Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature.
Poornima P, Kumar JD, Zhao Q, Blunder M, Efferth T. Poornima P, et al. Pharmacol Res. 2016 Sep;111:290-302. doi: 10.1016/j.phrs.2016.06.018. Epub 2016 Jun 18. Pharmacol Res. 2016. PMID: 27329331 Review.
In this review, we discuss the application of network pharmacology for cancer drug discovery. We provide an overview of the current state of knowledge on network pharmacology, focus on different technical approaches and implications for cancer therapy (e.g. polyphar …
In this review, we discuss the application of network pharmacology for cancer drug discovery. We provide an overview of the current s …
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